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NFATc1 and NFATc3 is Involved in the Expression of Receptor Activator of NF-kappaB Ligand in Activated T Lymphocytes

Heo SJ, Park HJ, Baek JH

  • KMID: 1431127
  • Int J Oral Biol.
  • 2013 Mar;38(1):37-42.
Receptor activator of NF-kappaB ligand (RANKL) is an essential cytokine for osteoclast differentiation, activation and survival. T lymphocytes such as T17 cells, a subset of T helper cells that produce...
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Altered Contractility of the in vivo Feline Trabecular Smooth Muscle under Acidosis

Moon DG, Kwak TI, Kim JJ

  • KMID: 2290151
  • Korean J Urol.
  • 1998 Aug;39(8):744-750.
PURPOSE: Previous studies concerning the ischemic priapism revealed that hypoxia alter the erectile and contractile responses of penis. But the effects of accompaning acidosis on the trabecular smooth muscle contractility...
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The Effect of Acethylcholine on the Slow Motility Induced by High Potassium Ion and Increased Intracellular Calcium in Outer Hair Cells

Cho YG, Lee SW, Ahn JH, Chung JW, Lee KS

  • KMID: 2275923
  • Korean J Otolaryngol-Head Neck Surg.
  • 2002 Jul;45(7):641-645.
BACKGROUND AND OBJECTIVES: It has been known that the motility of the outer hair cell controls the physiological characteristics of the organ of Corti. Motility can be divided into two...
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Screening of Low Molecular Metabolite, FS390 as an Inhibitor of Neurotransmitter Release from PC12 Cells

Chung YT, Kim HJ, Lee YS

  • KMID: 1937820
  • Korean J Anat.
  • 2006 Apr;39(2):91-102.
We established an in vitro experimental system using the following procedure. We first introduced tritium-labeled norepinephrine ([3H]-NE) into PC12 cells. The [3H]-NE incorporated-PC12 cells were stimulated by a high concentration...
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Swiprosin-1 Expression Is Up-Regulated through Protein Kinase C-theta and NF-kappaB Pathway in T Cells

Kim YD, Kwon MS, Na BR, Kim HR, Lee HS, Jun CD

Swiprosin-1 exhibits the highest expression in CD8+ T cells and immature B cells and has been proposed to play a role in lymphocyte biology through actin remodeling. However, regulation of...
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Effects of exogenous ATP on calcium mobilization and cell proliferation in C6 glioma cell

Lee EJ, Cha SH, Lee WK, Lee KH, Lee SB

  • KMID: 2285204
  • Korean J Physiol Pharmacol.
  • 1998 Aug;2(4):419-425.
To clarify the effect of extracellular ATP in cultured C6 glioma cells, ATP-induced cytosolic free calcium ((Ca2+)i) mobilization and cell proliferation were investigated. ATP-induced (Ca2+)i increased in a dose-dependent manner (10-7 M apprx...
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Effect about Neurite Extension of FS390, an Inhibitor of Exocytosis in Rat Hippocampal Neurons and PC12 Cells

Choi MK, Chon GH, Lee YS

  • KMID: 1937819
  • Korean J Anat.
  • 2006 Apr;39(2):81-90.
FS390, a novel microbial metabolite from Streptomyces spp. was identified as a small molecular substance and shown a inhibition activities for the release of neurotransmitter from rat hippocampal neuron and...
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Activation of K+ channel by 1-EBIO rescues the head and neck squamous cell carcinoma cells from Ca2+ ionophore-induced cell death

Yin MZ, Park SW, Kang TW, Kim KS, Yoo HY, Lee J, Hah JH, Sung MH, Kim SJ

Ion channels in carcinoma and their roles in cell proliferation are drawing attention. Intracellular Ca2+ ([Ca2+]i)-dependent signaling affects the fate of cancer cells. Here we investigate the role of Ca(2+)-activated...
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Effect of Parathyroid Hormone on the intracellular pH Regulation of Osteoblast-like Cells

Yoo CI, Lee JY, Bae HR, Kim KT, Kim BH

Intracellular pH regulation of osteoblasts is of a great importance in the process of bone formation and resorption, and has been suggested to be mediated via intracellular Ca2+ and cAMP...
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A Novel Cell Line for Screening of Immunosuppressor Specific to T Lymphocytes

Lee SK, Lim JH, Cho KM, Lee SH, Song YS, Chun HS, Son HJ

  • KMID: 2083003
  • Korean J Immunol.
  • 1997 Sep;19(3):375-382.
The systematic study of products from bacteria and fungi has led to the development of two immunosuppressive drugs, cyclosporin A and FK 506 (tacrolimus) which are useful to suppress adaptive...
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Intracellular Ca2+ Mobilization and Beta-hexosaminidase Release Are Not Influenced by 60 Hz-electromagnetic Fields (EMF) in RBL 2H3 Cells

Hwang YH, Song HS, Kim HR, Ko MS, Jeong JM, Kim YH, Ryu JS, Sohn UD, Gimm YM, Myung SH, Sim SS

The effects of extremely low frequency electromagnetic fields (EMF) on intracellular Ca2+ mobilization and cellular function in RBL 2H3 cells were investigated. Exposure to EMF (60 Hz, 0.1 or 1...
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Alpha-Melanocyte Stimulating Hormone Protects Pancreatic Islet Dysfunction by Peripheral Blood Mononuclear Cells in vitro

Jung EJ, Han DJ, Chang SH, Lim DG, Wee YM, Kim JH, Kim YH, Koo SK, Choi M, Park KT, Kim SC

  • KMID: 2003579
  • J Korean Soc Transplant.
  • 2006 Jun;20(1):41-48.
PURPOSE: The alpha-melanocyte-stimulating hormone (alpha-MSH) has been shown to interact with various cells of the immune and inflammatory system and down-regulate either the production or the action of the pro-inflammatory...
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The Number of NKT and NK Cells in Patients with Systemic Lupus Erythematosus is Decreased: Association with the Pathogenesis for SLE

Kim HL, Kim SG, Kim YS, Lee DS, Jung KC, Chung JH, Ahn C, Han JS, Kim S, Lee JS, Chung DH

  • KMID: 2079292
  • Korean J Nephrol.
  • 2003 Mar;22(2):205-212.
BACKGROUND: Systemic lupus erythematosus (SLE) is one of chronic autoimmune diseases of which the central pathophysiologic derangement has not been yet established. Recently, it has been suggested that immune-regulatory cells...
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A Case of Common Variable Immunodeficiency with Autoimmune Hemolytic Anemia

Lee KY, Lee YJ, Cha SW, Han JW, Whang KT, Kim JG

  • KMID: 1946282
  • J Korean Pediatr Soc.
  • 2000 Jan;43(1):117-122.
Common variable immunodeficiency (CVID) is a heterogeneous collection of disorders with hypogammaglobulinemia with recurrent bacterial infections and high incidence of autoimmune disorders as its hallmark. We report a 7-year-old girl...
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Elevated monocyte chemoattractant protein-1 in patients with Behcet's disease

Do JH, Jung JH, Park CS, Ko JS, Kim SS, Choi HC, Son JM, Min DJ, Park SH, Cho CS, Kim HY, Kim WU

  • KMID: 2080961
  • Korean J Med.
  • 2003 Oct;65(4):458-466.
BACKGROUND: Monocyte chemoattractant protein-1 (MCP-1) belongs to C-C subfamily of chemokines, which stimulates the migration of monocytes. MCP-1 exerts various effects on the monocytes, including the induction of integrin and...
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ATP-induced Calcium Mobilization and Proliferation in Cervical Cancer Cells

An WS, Le GH

  • KMID: 2261415
  • Korean J Obstet Gynecol.
  • 1999 Jun;42(6):1332-1338.
PURPOSE: Nucleotides such as ATP can act as extracellular effector molecules by interaction with specific cellular receptors. To know the role of nucleotides in cervical cancer cells, we observed the...
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