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T-cell immune response against cytomegalovirus in peripheral blood and colonic mucosa from ulcerative colitis and Crohn's disease patients

Nam SJ, Kim ES, Jeen YT

No abstract available.
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A rare cause of gastrointestinal hemorrhage

Lin WC, Chu CH

No abstract available.
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Hyperbaric oxygen therapy for pyoderma gangrenosum associated with ulcerative colitis

Seo HI, Lee HJ, Han KH

Pyoderma gangrenosum (PG), an ulcerating skin condition, is rare in patients with ulcerative colitis (UC). We report a case of successful treatment of PG in a patient with UC using...
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Duodenal amyloidosis secondary to ulcerative colitis

Park SW, Jee SR, Kim JH, Lee SH, Hwang JW, Jang JG, Lee DW, Seol SY

Amyloidosis is defined as the extracellular deposition of non-branching fibrils composed of a variety of serum-protein precursors. Secondary amyloidosis is associated with several chronic inflammatory conditions, such as rheumatologic or...
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A case of pemphigus vulgaris associated with ulcerative colitis

Seo JW, Park J, Lee J, Kim MY, Choi HJ, Jeong HJ, Lee JW, Jung SY, Kim WK

Pemphigus vulgaris is an autoimmune bullous disorder characterized by the production of autoantibodies against the intercellular space of the epithelium. It has rarely been reported in association with inflammatory bowel...
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Fecal microbiota transplantation for recurrent Clostridium difficile infection in a patient with ulcerative colitis

Nanki K, Mizuno S, Matsuoka K, Ono K, Sugimoto S, Kiyohara H, Arai M, Nakashima , Takeshita , Saigusa K, Senoh M, Fukuda T, Naganuma M, Kato H, Suda W, Hattori M, Kanai T

Fecal microbiota transplantation (FMT) has been reported as a safe and effective therapy in patients with refractory and recurrent Clostridium difficile infection (CDI). FMT has also been reported as a...
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Clinical outcomes of surveillance colonoscopy for patients with sessile serrated adenoma

Park SJ, Yoon H, Jung IS, Shin CM, Park YS, Kim NY, Lee DH

BACKGROUND/AIMS: Sessile serrated adenomas (SSAs) are known to be precursors of colorectal cancer (CRC). The proper interval of follow-up colonoscopy for SSAs is still being debated. We sought to determine...
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Three-year colonoscopy surveillance after polypectomy in Korea: a Korean Association for the Study of Intestinal Diseases (KASID) multicenter prospective study

Choi WS, Han DS, Eun CS, Park DI, Byeon JS, Yang DH, Jung SA, Lee SK, Hong SP, Park CH, Lee SH, Ji JS, Shin SJ, Keum B, Kim HS, Choi JH, Jung SH

BACKGROUND/AIMS: Colonoscopic surveillance is currently recommended after polypectomy owing to the risk of newly developed colonic neoplasia. However, few studies have investigated colonoscopy surveillance in Asia. This multicenter and prospective...
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Topographic, histological and molecular study of aberrant crypt foci identified in human colon in different clinical groups

Ghosh S, Gupta B, Verma P, Vishnubathla S, Pal S, Dash NR, Gupta SD, Das P

BACKGROUND/AIMS: Aberrant crypt foci (ACF) are early microscopic lesions of the colonic mucosa, which can be detected by magnified chromoendoscopy. Herein, we have investigated whether ACF identified in different clinical...
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Rapid and accurate diagnosis of Clostridium difficile infection by real-time polymerase chain reaction

Song PH, Min JH, Kim YS, Jo SY, Kim EJ, Lee KJ, Lee J, Sung H, Moon JS, Whang DH

BACKGROUND/AIMS: The incidence and severity of Clostridium difficile infection (CDI) have increased worldwide, resulting in a need for rapid and accurate diagnostic methods. METHODS: A retrospective study was conducted to compare...
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An analysis of dietary fiber and fecal fiber components including pH in rural Africans with colorectal cancer

Faruk M, Ibrahim S, Adamu A, Rafindadi , Ukwenya Y, Iliyasu Y, Adamu A, Aminu SM, Shehu MS, Ameh DA, Mohammed A, Ahmed SA, Idoko J, Ntekim A, Suleiman A, Shah KZ, Adoke KU

BACKGROUND/AIMS: Colorectal cancer (CRC) is now a major public health problem with heavy morbidity and mortality in rural Africans despite the lingering dietary fiber-rich foodstuffs consumption. Studies have shown that...
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Distribution of cytomegalovirus genotypes among ulcerative colitis patients in Okinawa, Japan

Nahar S, Hokama A, Iraha A, Ohira T, Kinjo T, Hirata T, Kinjo T, Parrott GL, Fujita J

BACKGROUND/AIMS: To determine the prevalence of glycoprotein B (gB), glycoprotein N (gN), and glycoprotein H (gH) genotypes of human cytomegalovirus (HCMV) superimposed on ulcerative colitis (UC) patients in Japan. METHODS: Four...
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Efficacy and safety of the adalimumab biosimilar Exemptia as induction therapy in moderate-to-severe ulcerative colitis

Midha V, Mahajan R, Mehta V, Narang V, Singh A, Kaur K, Sood A

BACKGROUND/AIMS: Data on the efficacy and safety of the adalimumab biosimilar Exemptia are limited. METHODS: Patients with moderate-to-severe active steroid-refractory ulcerative colitis (UC) treated at Dayanand Medical College and Hospital, India...
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Efficacy of restarting anti-tumor necrosis factor α agents after surgery in patients with Crohn's disease

Hiraoka S, Takashima , Kondo Y, Inokuchi T, Sugihara Y, Takahara M, Kawano S, Harada K, Kato J, Okada H

BACKGROUND/AIMS: The efficacy of anti-tumor necrosis factor α (anti-TNFα) antibodies for postoperative Crohn's disease (CD) in patients who were treated with these agents prior to surgery is largely unknown. METHODS: CD...
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Are Truelove and Witts criteria for diagnosing acute severe colitis relevant for the Indian population? A prospective study

Jain S, Kedia S, Bopanna S, Yadav DP, Goyal S, Sahni P, Pal S, Dash NR, Makharia G, Travis SP, Ahuja V

BACKGROUND/AIMS: Truelove and Witts criteria have been used to define acute severe colitis since the 1950s. However, hemoglobin (an additional criterion of the definition) levels in the general population in...
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Comparison of time until elective intestinal resection regarding previous anti-tumor necrosis factor exposure: a Brazilian study on patients with Crohn's disease

Kotze PG, Magro DO, Saab B, Saab MP, Pinheiro L, Olandoski , Ayrizono M, Martinez C, Coy CS

BACKGROUND/AIMS: The use of anti-tumor necrosis factor (anti-TNF) agents seems to reduce surgical rates and delay surgical procedures in prospective trials and population-based studies in the management of Crohn's disease...
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Association of endoscopic and histological remission with clinical course in patients of ulcerative colitis

Narang V, Kaur R, Garg B, Mahajan R, Midha V, Sood N, Sood A

BACKGROUND/AIMS: The therapeutic goal for treating ulcerative colitis (UC) patients has shifted to achieving mucosal healing over the past few years. However, at present, limited data is available on the...
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Quality is the key for emerging issues of population-based colonoscopy screening

Yoon JY, Cha JM, Jeen YT, on behalf of Medical Policy Committee of Korean Association for the Study of Intestinal Diseases (KASID), Quality Improvement Committee of Korean Society of Gastrointestinal Endoscopy (KSGE)

Colonoscopy is currently regarded as the gold standard and preferred method of screening for colorectal cancer (CRC). However, the benefit of colonoscopy screening may be blunted by low participation rates...
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Quality indicators in inflammatory bowel disease

Berry SK, Melmed GY

Inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, is a chronic, debilitating, and expensive condition affecting millions of people globally. There is significant variation in the quality...
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Immunological pathogenesis of inflammatory bowel disease

Lee SH, Kwon JE, Cho ML

Inflammatory bowel disease (IBD) is a chronic inflammatory state of the gastrointestinal tract and can be classified into 2 main clinical phenomena: Crohn's disease (CD) and ulcerative colitis (UC). The...
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