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LIPUS Promotes Endothelial Differentiation and Angiogenesis of Periodontal Ligament Stem Cells by Activating Piezo1

Hu R, Yang Zy, Li Yh, Zhou Z

Background and Objectives: Low-intensity pulsed ultrasound (LIPUS) promotes differentiation and regulates biological functions of various stem cells, but its effect on the endothelial differentiation of periodontal ligament stem cells (PDLSCs)...
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Generation of Urothelial Cells from Mouse-Induced Pluripotent Stem Cells

Zhang D, Sun F, Yao H, Wang D, Bao X, Wang J, Wu J

Background and Objectives: The search for a suitable alternative for urethral defect is a challenge in the field of urethral tissue engineering. Induced pluripotent stem cells (iPSCs) possess multipotential for...
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NBCe1 Regulates Odontogenic Differentiation of Human Dental Pulp Stem Cells via NF-κB

Li Q, Ju Y, Jin C, Liu L, Zhao S

Background and Objectives: Dental pulp stem cells (DPSCs) play an important role in the repair of tooth injuries. Electrogenic sodium bicarbonate cotransporter 1 (NBCe1) is a Na+ -coupled HCO3− transporter...
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MSCs-Derived miR-150-5p-Expressing Exosomes Promote Skin Wound Healing by Activating PI3K/AKT Pathway through PTEN

Xiu C, Zheng H, Jiang M, Li J, Zhou Y, Mu L, Liu W

Background and Objectives: The goal of this study was to investigate the mechanism of mesenchymal stem cell (MSC)-derived microRNA (miR)-150-5p-expressing exosomes in promoting skin wound healing through activating PI3K/AKT pathway...
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Transcriptomic Comparison Analysis between Ameloblastoma and AM-1 Cell Line

Li S, Lee DJ, Kim HY, Harada H, Jung YS, Jung HS

Cancer initiation and progression are profoundly along with the crosstalk between cancer cells and the surrounding stroma. Accumulating evidence has shown that the therapy targeting the extracellular matrix (ECM) would...
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Cannabidiol Promotes Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in the Inflammatory Microenvironment via the CB2-dependent p38 MAPK Signaling Pathway

Li L, Feng J, Sun L, Xuan Yw, Wen L, Li Yx, Yang S, Zhu B, Tian Xy, Li S, Zhao Ls, Dang Rj, Jiao T, Zhang Hs, Wen N

Background and Objectives: Chronic inflammation of bone tissue often results in bone defects and hazards to tissue repair and regeneration. Cannabidiol (CBD) is a natural cannabinoid with multiple biological activities,...
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Human Umbilical Cord-Derived Mesenchymal Stem Cells Repair SU5416-Injured Emphysema by Inhibiting Apoptosis via Rescuing VEGF-VEGFR2-AKT Pathway in Rats

Chen Q, Lv L, Zheng C, Pan H, Xu J, Lin J, Deng Z, Qian W

Background and Objectives: Chronic obstructive pulmonary disease (COPD) is a common, frequently-occurring disease and poses a major health concern. Unfortunately, there is current no effective treatment for COPD, particularly emphysema....
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