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Extracellular HIV-1 Tat enhances monocyte adhesion by up-regulation of ICAM-1 and VCAM-1 gene expression via ROS-dependent NF-kappaB activation in astrocytes

Song HY, Ryu J, Ju SM, Park LJ, Lee JA, Choi SY, Park J

  • KMID: 1103678
  • Exp Mol Med.
  • 2007 Feb;39(1):27-37.
One of characteristic features of AIDS-related encephalitis and dementia is the infiltration of monocytes into the CNS. HIV-1 Tat was demonstrated to facilitate monocyte entry into the CNS. In this...
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Expression of ICAM-1 on the Hantaan virus-infected human umbilical vein endothelial cells

Song JS, Min CH, Kang E, Yu SH

  • KMID: 760334
  • Korean J Intern Med.
  • 1999 Jul;14(2):47-54.
OBJECTIVES: In HFRS, there is a varying degree of disseminated intravascular coagulation which was evident in the early phase of the illness. It is believed also that DIC...
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Prior Ischemic Treatment Renders Kidney Resistant to Subsequent Ischemia

Park KM, Han HJ

  • KMID: 1095370
  • J Vet Sci.
  • 2002 Jun;3(2):115-121.
Prior ischemia leads to resistance against subsequent ischemic insults. The mechanisms that underlie this adaptive response remain unidentified. Thus, we studied whether the reduced susceptibility of mice previously subjected to...
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Inhibitory Effect of Melanoma Differentiation Associated Gene-7/Interleukin-24 on Invasion In Vitro of Human Melanoma Cancer Cells

Lin BW, Jiao ZL, Fan JF, Peng L, Li L, Zhao ZG, Ding XY, Li HJ

The acquisition of metastasis potential is a critical point for malignant tumors. Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24) is a potential tumor suppress gene and frequently down-regulated in malignant tumors. It...
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Statin inhibits interferon-gamma-induced expression of intercellular adhesion molecule-1 (ICAM-1) in vascular endothelial and smooth muscle cells

Chung HK, Lee IK, Kang HK, Suh JM, Kim H, Park KC, Kim DW, Kim YK, Ro HK, Shong MH

  • KMID: 1121099
  • Exp Mol Med.
  • 2002 Dec;34(6):451-461.
Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, known as statins, are widely used for primary and secondary prevention of coronary artery atherosclerosis. Pathogenesis of atherosclerosis is multistep processes where...
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RANKL stimulates proliferation, adhesion and IL-7 expression of thymic epithelial cells

Lee HW, Park HK, Na YJ, Kim CD, Lee JH, Kim BS, Kim JB, Lee CW, Moon JO, Yoon S

Abstract In many clinical situations which cause thymic involution and thereby result in immune deficiency, T cells are the most often affected, leading to a prolonged deficiency of T cells. Since...
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Targeted resequencing of candidate genes reveals novel variants associated with severe Behcet's uveitis

Kim SJ, Lee S, Park C, Seo JS, Kim JI, Yu HG

  • KMID: 2154268
  • Exp Mol Med.
  • 2013 Oct;45(10):e49.
Behcet's disease (BD) is a chronic systemic inflammatory disorder characterized by four major manifestations: recurrent uveitis, oral and genital ulcers and skin lesions. To identify some pathogenic variants associated with...
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Gamma Linolenic Acid Exerts Anti-Inflammatory and Anti-Fibrotic Effects in Diabetic Nephropathy

Kim DH, Yoo TH, Lee SH, Kang HY, Nam BY, Kwak SJ, Kim JK, Park JT, Han SH, Kang SW

PURPOSE: This study was undertaken to investigate the effects of gamma linolenic acid (GLA) on inflammation and extracellular matrix (ECM) synthesis in mesangial and tubular epithelial cells under diabetic conditions. MATERIALS...
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Chemokines, osteopontin, ICAM-1 gene expression in cultured rat mesangial cells

Lee SK, Park JY, Chung SJ, Yang WS, Kim SB, Park SK, Park JS

To investigate whether MCP-1, CINC, RANTES, osteopontin and ICAM-1 mRNA could be induced in cultured rat mesangial cells by interleukin-1beta(IL-1beta), tumor necrosis factor-alpha (TNF-alpha) and lipopolysaccharide (LPS), and whether ...
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Hepatic Ischemic Preconditioning Provides Protection Against Distant Renal Ischemia and Reperfusion Injury in Mice

Lee JA, Choi JW, In JH, Jung HS, Kim YS, Jeon YS, Kang YJ, Kim DW, Lim YG, Park JH, Joo JD

We previously demonstrated that there are acute and delayed phases of renal protection against renal ischemia and reperfusion (IR) injury with renal ischemic preconditioning (IPC). This study assessed whether hepatic...
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Morphine Postconditioning Attenuates ICAM-1 Expression on Endothelial Cells

Min TJ, Kim JI, Kim JH, Noh KH, Kim TW, Kim WY, Lee YS, Park YC

The purpose of this study is to determine 1) whether morphine postconditiong (MPostC) can attenuate the intercellular adhesion molecules-1 (ICAM-1) expression after reoxygenation injury and 2) the subtype(s) of the...
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