- Comparison of the Activities of NF-kappa B and I kappa B alpha in Patients with Rheumatoid Arthritis and Osteoarthritis
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Ha NK, Kwon SY, Koh HS, Sohn JM, Kim JY, Oh SC, Shin YH, Han CW
- KMID: 1848282
- J Korean Orthop Res Soc.
- 2004 Oct;7(2):125-132.
PURPOSE: The nuclear factor-kappa B (NF-kappa B) has been known to regulate the inflammatory and immune process by transcription of inflammatory intermediates. The purpose of the present study is to... -
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- Roles of ERK and NF-kappa B in Interleukin-8 Expression in Response to Heat Shock Protein 22 in Vascular Smooth Muscle Cells
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Kang SH, Lee JH, Choi KH, Rhim BY, Kim K
- KMID: 1838355
- Korean J Physiol Pharmacol.
- 2008 Aug;12(4):171-176.
- doi: 10.4196/kjpp.2008.12.4.171
Heat shock proteins (HSPs) serve as molecular chaperones and play a role in cell protection from damage in response to stress stimuli. The aim of this article is to investigate... -
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- Nuclear Factor-kappa B Activation and Chemokine Genes Expression in HT-29 Intestinal Epithelial Cells in Response to Clostridium difficile Toxin A Stimulation
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Lee JY, Yoon YM, Roh HC, Kim JM
- KMID: 1574164
- J Bacteriol Virol.
- 2005 Sep;35(3):217-226.
Intestinal epithelial cells are known to up-regulate the expression of several chemokines in response to bacterial toxins. Since there has been little understanding on the cellular mechanisms of C. difficile... -
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- Expression of NF-K B and I-K B in Allergic Rhinitis
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Kim ST, Oh SC, Kim CW, Park C, Jang IH, Cha HE, Hwang YJ
- KMID: 2274764
- Korean J Otolaryngol-Head Neck Surg.
- 2000 Nov;43(11):1191-1195.
BACKGROUND AND OBJECTIVES: K B is a transcription factor in immune and inflammatory reactions, and exerts its effect by expressing cytokines and chemokines, enzymes, receptors and adhesion molecules. Many of... -
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- Resveratrol Inhibits Nitric Oxide-Induced Apoptosis via the NF-Kappa B Pathway in Rabbit Articular Chondrocytes
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Eo SH, Cho H, Kim SJ
- KMID: 2048307
- Biomol Ther.
- 2013 Sep;21(5):364-370.
Resveratrol (trans-3,4'-trihydroxystillbene), a naturally occurring polyphenolic antioxidant found in grapes and red wine, elicits diverse biochemical responses and demonstrates anti-aging, anti-inflammatory, and anti-proliferative effects in several cell types. Previously, resveratrol... -
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- Flowers of Inula japonica Attenuate Inflammatory Responses
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Choi JH, Park YN, Li Y, Jin MH, Lee J, Lee Y, Son JK, Chang HW, Lee E
- KMID: 1456218
- Immune Netw.
- 2010 Oct;10(5):145-152.
- doi: 10.4110/in.2010.10.5.145
BACKGROUND: The flowers of Inula japonica (Inulae Flos) have long been used in traditional medicine for the treatment of inflammatory diseases. In the present study, we investigated the anti-inflammatory properties... -
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- Degradation of the Transcription Factors NF-kappaB, STAT3, and STAT5 Is Involved in Entamoeba histolytica-Induced Cell Death in Caco-2 Colonic Epithelial Cells
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Kim KA, Min A, Lee YA, Shin MH
- KMID: 1792210
- Korean J Parasitol.
- 2014 Oct;52(5):459-469.
- doi: 10.3347/kjp.2014.52.5.459
Entamoeba histolytica is a tissue-invasive protozoan parasite causing dysentery in humans. During infection of colonic tissues, amoebic trophozoites are able to kill host cells via apoptosis or necrosis, both of... -
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- Black rice anthocyanidins prevent retinal photochemical damage via involvement of the AP-1/NF-kappaB/Caspase-1 pathway in Sprague-Dawley Rats
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Jia H, Chen W, Yu X, Wu X, Li S, Liu H, Liao J, Liu W, Mi M, Liu L, Cheng D
- KMID: 1705566
- J Vet Sci.
- 2013 Sep;14(3):345-353.
- doi: 10.4142/jvs.2013.14.3.345
The effects of black rice anthocyanidins (BRACs) on retinal damage induced by photochemical stress are not well known. In the present study, Sprague-Dawley rats were fed AIN-93M for 1 week,... -
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- Glucocorticoid Mechanism of Inhibition of the Inflammatory Cells in Lumbar Intervertebral Disc Cells Stimulated by TNF-alpha Production of Nuclear Factor-kappaB
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Oh IS, Park SE, Son JM, Chung JY, Kim YY
- KMID: 1455857
- J Korean Orthop Res Soc.
- 2010 Dec;13(2):80-87.
PURPOSE: To analyze the action mechanism of NF-kappaB, IkappaB-alpha and effect of the Dexamethasone (DEXA) in mediating this inflammation, after stimulating cultured herniated intervertebral disc cells with TNF-alpha. MATERIALS AND METHODS:... -
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- Curcumin suppresses the production of interleukin-6 in Prevotella intermedia lipopolysaccharide-activated RAW 264.7 cells
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Kim SJ
- KMID: 1783607
- J Periodontal Implant Sci.
- 2011 Jun;41(3):157-163.
- doi: 10.5051/jpis.2011.41.3.157
PURPOSE: Curcumin is known to exert numerous biological effects including anti-inflammatory activity. In this study, we investigated the effects of curcumin on the production of interleukin-6 (IL-6) by murine macrophage-like... -
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- Peroxisome Proliferator-Activated Receptor gamma Agonists Inhibit the Expression of Monocyte Chemoattractant Protein-1 in Human Mesangial Cells
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Kim YS, Kim YO, Yoon SA, Yang CW, Kim YS, Chang YS, Bang BK
- KMID: 2254879
- Korean J Nephrol.
- 2004 Nov;23(6):859-866.
BACKGROUND: PPAR gamma is a member of the nuclear hormone receptor superfamily of transcription factors. PPAR gamma plays an important role in the control of inflammation as well as numerous... -
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- The Stem Bark of Kalopanax pictus Exhibits Anti-inflammatory Effect through Heme Oxygenase-1 Induction and NF-kappaB Suppression
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Bang SY, Park GY, Park SY, Kim JH, Lee YK, Lee SJ, Kim Y
- KMID: 2150677
- Immune Netw.
- 2010 Dec;10(6):212-218.
- doi: 10.4110/in.2010.10.6.212
BACKGROUND: The stem bark of Kalopanax pictus (KP) has been used in traditional medicine to treat rheumatoidal arthritis, neurotic pain and diabetes mellitus in China and Korea. In this study,... -
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- The Proteasome Inhibitor MG132 Sensitizes Lung Cancer Cells to TRAIL-induced Apoptosis by Inhibiting NF-kappaB Activation
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Seo PW, Lee KY
- KMID: 2319129
- Tuberc Respir Dis.
- 2008 Dec;65(6):476-486.
BACKGROUND: TRAIL (TNF-related apoptosis inducing ligand) is a newly identified member of the TNF gene family which appears to have tumor-selective cytotoxicity due to the distinct decoy receptor system. TRAIL... -
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- Role of Insulin in the Activation of NF-kappaB/IkappaB Pathway in Macrophage Cells
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Lee SM, Jang YS, Lee CT, Kim YW, Han SK, Shim YS, Yoo CG
- KMID: 1728962
- Tuberc Respir Dis.
- 2010 Mar;68(3):168-174.
- doi: 10.4046/trd.2010.68.3.168
BACKGROUND: Sepsis still has a high mortality rate despite adequate supportive care. Newer therapeutic modalities have been developed but they have generally ended in failure. Recently, insulin was reported to... -
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- NF-kappaB Binding Activity and Cyclooxygenase-2 Expression in Persistent betaCCI(4)-Treated Rat Liver Injury
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Kim SH, Chu HJ, Kang DH, Song GA, Cho M, Yang US, Kim HJ, Chung HY
- KMID: 648675
- J Korean Med Sci.
- 2002 Apr;17(2):193-200.
- doi: 10.3346/jkms.2002.17.2.193
The involvement of NF-kappaB binding activity is known to be important in the mechanism of acute liver injury and in the induction of cyclooxygenase (COX-2). This study was performed to... -
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- Ginsenoside Rg2 Inhibits Lipopolysaccharide-Induced Adhesion Molecule Expression in Human Umbilical Vein Endothelial Cell
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Cho YS, Kim CH, Ha TS, Lee SJ, Ahn HY
- KMID: 1429384
- Korean J Physiol Pharmacol.
- 2013 Apr;17(2):133-137.
- doi: 10.4196/kjpp.2013.17.2.133
Vascular cell adhesion molecule 1 (VCAM-1), intercellular adhesion molecule 1 (ICAM-1), P- and E-selectin play a pivotal role for initiation of atherosclerosis. Ginsenoside, a class of steroid glycosides, is abundant... -
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- Protein Kinase C-alpha Regulates Toll-like Receptor 4-Mediated Inducible Nitric Oxide Synthase Expression
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Lee JG, Chin BR, Baek SH
- KMID: 1485993
- J Korean Assoc Oral Maxillofac Surg.
- 2008 Feb;34(1):28-35.
PURPOSE: The nitric oxide (NO) release by inducible nitric oxide synthase (iNOS) is the key events in macrophage response to lipopolysaccharide (LPS) which is suggested to be a crucial mediator... -
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- Aggregatibacter actinomycetemcomitans Strongly Stimulates Endothelial Cells to Produce Monocyte Chemoattractant Protein-1 and Interleukin-8
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Choi EK, Kang MS, Oh BH, Kim SY, Kim SH, Kang IC
- KMID: 1436488
- Int J Oral Biol.
- 2012 Sep;37(3):137-145.
Aggregatibacter actinomycetemcomitans is the most important etiologic agent of aggressive periodontitis and can interact with endothelial cells. Monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8) are chemokines, playing important roles in... -
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- Epigallocatechin-3-gallate Inhibits LPS-Induced NF-kappaB and MAPK Signaling Pathways in Bone Marrow-Derived Macrophages
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Joo SY, Song YA, Park YL, Myung E, Chung CY, Park KJ, Cho SB, Lee WS, Kim HS, Rew JS, Kim NS, Joo YE
- KMID: 2284263
- Gut Liver.
- 2012 Apr;6(2):188-196.
BACKGROUND/AIMS: Epigallocatechin-3-gallate (EGCG), the primary catechin in green tea, has anti-inflammatory and anti-oxidative properties. The aim of the current study was to characterize the impact of EGCG on lipopolysaccharide (LPS)-induced... -
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- Coptidis rhizoma extract protects against cytokine-induced death of pancreatic beta-cells through suppression of NF-kappa B activation
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Kim EK, Kwon KB, Han MJ, Song MY, Lee JH, Lv N, Ka SO, Yeom SR, Kwon YD, Ryu DG, Kim KS, Park JW, Park R, Park BH
- KMID: 1094655
- Exp Mol Med.
- 2007 Apr;39(2):149-159.
We demonstrated previously that Coptidis rhizoma extract (CRE) prevented S-nitroso-N-acetylpenicillamine-induced apoptotic cell death via the inhibition of mitochondrial membrane potential disruption and cytochrome c release in RINm5F (RIN) rat insulinoma... -
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