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Production and characterization of human T cell hybridomas

Hwang ES, Lim DG, Lee AY, Seoh JY, Park CG, Kook YH, Choi MS, Cha CY

  • KMID: 1688027
  • J Korean Soc Microbiol.
  • 1992 Dec;27(6):571-577.
No abstract available.
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Preferential production of IgM-secreting hybridomas by immunization with DNA vaccines coding for Ebola virus glycoprotein: use of protein boosting for IgG-secreting hybridoma production

Lee SH, Han BS, Choe J, Sin JI

PURPOSE: The goal of this study was to investigate the utility of DNA vaccines encoding Ebola virus glycoprotein (GP) as a vaccine type for the production of GP-specific hybridomas and...
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Regulation of cellular immunity in cryptococcosis III. induction ofcryptococcus neoformans-specific T cells and hybridoma

Ha TY, Park YM, Park YK, Lee HK, Park CW

  • KMID: 2082965
  • Korean J Immunol.
  • 1992 May;14(1):15-23.
No abstract available.
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Production and Characterization of Anti-Staphylococcal Toxic Shock Syndrome Toxin-1 Monoclonal Antibody

Park JS, Kim JS, Yi J, Kim EC

BACKGROUND: Recently the association between the virulence factors of Staphylococcus aureus and the outcome of the patients infected with the organism appears to be the subject of active investigation. Toxic...
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Development of monoclonal antibody against Porphyromonas gingivalis heat shock protein

Yi NN, Lee JY, Kim SJ, Choi JI

Heat shock protein (HSP) is one of cellular protein commonly present in major periodontopathogenic bacteria as well as mammalian cells. The protein may play a role in the immunopathogenesis by...
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T Cell Epitope Analysis of Structural Protein of Adenovirus

Hwang JW, Kim MH, Kim KH

  • KMID: 1557251
  • Korean J Immunol.
  • 1998 Dec;20(4):435-442.
Thelper (Th) cells play a pivotal role in the regulation of immune responses. Since Th epitopes in adenovirus have not yet been defined, in this study, it was attempted to...
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Purification and characterization of monoclonal IgG antibodies recognizing Ebola virus glycoprotein

Han BS, Jang HY, Racine T, Qiu X, Sin JI

PURPOSE: The goal of this study was to purify and characterize Ebola virus glycoprotein (GP)-specific IgG antibodies from hybridoma clones. MATERIALS AND METHODS: For hybridoma production, mice were injected by intramuscular-electroporation...
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Expression of human norovirus VP1 gene and VP1-specific monoclonal antibodies

Kim JW, Kong YJ, Kim MS, Lee HJ, Lee SW, Kang SY

Norovirus (NoV) is an etiologic agent of human and animal acute gastroenteritis and is a member of the family Caliciviridae. NoV is classified based on nucleotide sequences of the VP1...
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Production and characterization of cross-reactive anti-Porphyromonas gingivalis heat shock protein 60 monoclonal antibody

Choi JI, Kim SJ, Lee JY, Lee JY

PURPOSE: Porphyromonas gingivalis (P. gingivalis) heat shock protein (HSP)60 may play a role in the immunopathogenesis of periodontitis as well as atherosclerosis by modulating autoimmune reaction due to its high...
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From rabbit antibody repertoires to rabbit monoclonal antibodies

Weber J, Peng H, Rader C

In this review, we explain why and how rabbit monoclonal antibodies have become outstanding reagents for laboratory research and increasingly for diagnostic and therapeutic applications. Starting with the unique ontogeny...
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Production and Characterization of Monoclonal Antibodies Against Seoul Virus

Lee HW, Lee YJ, Song KJ, Kee SH, Choi YJ, Song JW, Cho HW

  • KMID: 2146935
  • J Korean Soc Microbiol.
  • 1998 Feb;33(1):27-38.
Hantaviruses are members of the family Bunyaviridae, the etiologic agents of Hemorrhagic fever with renal syndrome (HFRS) and Hantavirus Pulmonary Syndrome (HPS). They are negative-sense, single-stranded RNA viruses possessing a...
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Development of a New Nonoclonal Antibody CC5 Using a Cervical Carcinoma Cell-line Derived From Korean Woman

Kim JW, Seo CO, Cho EY, Kim HK, Kim SJ, Hur SY, Kim YW, Park TC, Lee JM, Namkoong S

  • KMID: 2175196
  • J Korean Cancer Assoc.
  • 1999 Jun;31(3):562-574.
PURPOSE: Cancer of the uterine cervix remains the leading cause of cancer death in Korean women. Conventional examinations still have limitations with regards to sensitivity and specificity in diagnosis and...
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Characterization of Monoclonal Antibody Specific for Hepatitis C Virus E2 Envelope Protein

Park JS, Lee BY, Chung SI, Min MK

  • KMID: 2204561
  • J Korean Soc Virol.
  • 1997 Mar;27(1):9-17.
Hepatitis C virus (HCV) E2 protein is known to be one of putative envelope proteins. To develop a sensitive detection method for HCV infected tissues and cells, monoclonal antibodys (MAbs)...
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Production of the Monoclonal Antibodies against Bartonella henselae Isolated from a Korean Patient

Kil SH, Kang JS

Bartonellosis is spotlighted recently as an emerging zoonosis and Bartonella henselae is reported to be the main infectious agent. In Korea, however, few studies have been made on the epidemiology...
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Monoclonal antibody production and characterization for the measurement of plasma high density lipoprotein

Lee SH, Cho MH

We prepared two monoclonal antibodies-A-I30 and A-I4 to HDL apo A-I-with the ultimate goals of expressing and overproducing the valuable immunodiagnostic single chain Fv by phage display libraries in E,...
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Brain Tumor Immunology: Part II : Immunotherapy of Malignant Brain Tumors

Hong YK, Rha HK, Jung CK, Lee SW, Jo TH, Baik MW, Yoon SH, Kang JK, Song JU, Choi CR

  • KMID: 2067857
  • J Korean Neurosurg Soc.
  • 1990 Dec;19(10-12):1389-1396.
The prognosis of patients with malignant brain tumors has improved only slightly despite the combined use of surgery, radiation therapy, and chemotherapy. Immunotherapy offers some possibilities and hopes as a...
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Effect of Anti - idiotype Antibody on Anti - DNA Antibody Production by Hybridoma Cells

Youn JK, Kim HI, Kim JD, Park S, Kim YT, Lee MN

  • KMID: 1548376
  • Korean J Immunol.
  • 1997 Dec;19(4):513-524.
Anti-idiotype antibody (anti-id Ab) which recognizes idiotope in the variable region of immunoglobulin (Ig) can regulate Ab production by B cells in vivo and in vitro. Although it has been...
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Production of CD44v6 Antibody Fragments and Comparision of Their Speciticities

Han I, Zeon SK, Park KK

  • KMID: 1550740
  • Korean J Immunol.
  • 1999 Dec;21(4):303-309.
CD44v6 was known as tumor marker for tumor progression and metastasis in various kinds of carcinomas. The CD44v6 monoclonal antibody was produced by cell cultures or mouse ascite fluids using...
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Production of Monoclonal Antibody Against Human 14 - 3 - 3 Zeta Isoform Expressed in Escherichia coli

Lim BU, Kang JS, Kim JW, Choi NJ

  • KMID: 2083005
  • Korean J Immunol.
  • 1997 Sep;19(3):391-398.
14-3-3 proteins are cytoplasmic proteins of about 29 kDa and have a minimum of seven isoforms. This protein is important in signal transduction with the ability of binding with phosphoserine...
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Generation and Characterization of Monoclonal Antibodies against Human Interferon-lambda1

Hong SH, Kim JS, Park S

BACKGROUND: Members belonging to the interferon-lambda (IFN-lambda) family exert protective action against viral infection; however, the mechanisms of their action have remained elusive. To study IFN-lambda biology, such as endocytosis...
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