- Effect of kainic acid on the phosphorylation of mitogen activated protein kinases in rat hippocampus
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Won JS, Lee JK, Choi SS, Song DK, Huh SO, Kim YH, Suh HW
- KMID: 1607133
- Korean J Physiol Pharmacol.
- 2001 Dec;5(6):451-456.
In rat hippocampus, kainic acid (KA; 10 mg/kg; i.p.) increased the phosphorylated forms of ERK1/2 (p-ERK1/2) and Jun kinase1 (p-JNK1), but not p-JNK2 and p38 (p-p38). The preadministration with cycloheximide... -
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- A Winged-Helix Transcription Factor Foxg1 Induces Expression of Mss4 Gene in Rat Hippocampal Progenitor Cells
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Nam JS, Yang H, Kim NH, Sun Y, Choi BS, Huh SO
- KMID: 1460703
- Exp Neurobiol.
- 2010 Sep;19(2):75-82.
- doi: 10.5607/en.2010.19.2.75
Foxg1 (previously named BF1) is a winged-helix transcription factor with restricted expression pattern in the telencephalic neuroepithelium of the neural tube and in the anterior half of the developing optic... -
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- Apoptotic Effects of Melandryum firmum Root Extracts in Human SH-SY5Y Neuroblastoma Cells
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Rahman MA, Yang H, Lim SS, Huh SO
- KMID: 2165483
- Exp Neurobiol.
- 2013 Sep;22(3):208-213.
- doi: 10.5607/en.2013.22.3.208
Melandryum firmum is a biennial plant that has been used in traditional medicine for treatment of bacterial and fungal infection. Here, we investigated molecular mechanisms underlying apoptotic effects of Melandryum... -
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- Angiotropic metastatic malignant melanoma in a canine mammary gland
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Yang HJ, Lee EM, Kim AY, Lee EJ, Hong IH, Huh SO, Jeong KS
- KMID: 1444970
- Lab Anim Res.
- 2011 Dec;27(4):353-356.
- doi: 10.5625/lar.2011.27.4.353
An eleven-year-old spayed female Yorkshire Terrier presented with a sublumbar mass and upon ultrasonographic examination, was revealed to have a mammary gland tumor. Black to reddish colored masses, located in... -
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- Enhancement of Short-Term Memory by Methyl-6-(Phenylethynyl)-Pyridine in the BTBR T+tf/J Mouse Model of Autism Spectrum Disorder
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Yang H, Huh SO, Hong JS
- KMID: 2407111
- Endocrinol Metab.
- 2015 Mar;30(1):98-104.
- doi: 10.3803/EnM.2015.30.1.98
BACKGROUND: Autism spectrum disorder (ASD) encompasses a range of disorders that are characterized by social and communication deficits and repetitive behaviors. This study evaluated the effect of methyl-6-(phenylethynyl)-pyridine (MPEP), an... -
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- Antiproliferative and Cytotoxic Effects of Resveratrol in Mitochondria-Mediated Apoptosis in Rat B103 Neuroblastoma Cells
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Rahman MA, Kim NH, Kim SH, Oh SM, Huh SO
- KMID: 1493964
- Korean J Physiol Pharmacol.
- 2012 Oct;16(5):321-326.
- doi: 10.4196/kjpp.2012.16.5.321
Resveratrol, a natural compound, has been shown to possess anti-cancer, anti-aging, anti-inflammatory, anti-microbial, and neuroprotective activities. In this study, we examined the antiproliferative and cytotoxicity properties of resveratrol in Rat... -
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- Farnesylation-defective Rheb Increases Axonal Length Independently of mTORC1 Activity in Embryonic Primary Neurons
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Choi S, Sadra A, Kang J, Ryu JR, Kim JH, Sun W, Huh SO
- KMID: 2450212
- Exp Neurobiol.
- 2019 Apr;28(2):172-182.
- doi: 10.5607/en.2019.28.2.172
Rheb (Ras homolog enriched in the brain) is a small GTPase protein that plays an important role in cell signaling for development of the neocortex through modulation of mTORC1 (mammalian-target-of-rapamycin-complex-1)... -
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- Antidiabetic and Beta Cell-Protection Activities of Purple Corn Anthocyanins
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Hong SH, Heo JI, Kim JH, Kwon SO, Yeo KM, Bakowska-Barczak AM, Kolodziejczyk P, Ryu OH, Choi MK, Kang YH, Lim SS, Suh HW, Huh SO, Lee JY
- KMID: 2170674
- Biomol Ther.
- 2013 Jul;21(4):284-289.
Antidiabetic and beta cell-protection activities of purple corn anthocyanins (PCA) were examined in pancreatic beta cell culture and db/db mice. Only PCA among several plant anthocyanins and polyphenols showed insulin... -
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