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Characteristics of poisoning in younger children according to different forms of the drugs

Jang M, Ko Y, Yang HW, Lee J

PURPOSE: This study aimed to investigate the characteristics of poisoning drug ingested by younger children, and to compare the clinical outcome by drug forms. METHODS: This was a retrospective analysis based...
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Anaphylaxis to Chlorpheniramine Maleate and Literature Review

Choi YW, Jung MJ, Kim HO, Chung BY, Park CW

Chlorpheniramine maleate is commonly used antihistamine. Since antihistamines are the main therapeutic agents for symptomatic treatment of urticaria, anaphylaxis to antihistamines may lead to errors in diagnosis and treatment. We...
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Synergistic Effect of H1-Antihistamines on Topical Corticosteroids for Pruritus in Atopic Dermatitis: A Systematic Review and Meta-Analysis

Hur MS, Choe YB, Ahn KJ, Lee YW

BACKGROUND: Although oral antihistamines (H1-histamine receptor antagonists) are the main treatment option for pruritus in general skin dermatosis, their effect in treating pruritus of atopic dermatitis (AD) has not yet...
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Scombroid Fish Poisoning and Histamine Food Poisoning

Chung SP

Scombroid fish poisoning (SFP) is a form of histamine food poisoning caused by the ingestion of improperly stored fish. The term “scombroid” derives from the family name of the fish...
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Omalizumab as a Succesfull Therapy in Normocomplementemic Urticarial Vasculitis: A Series of Four Patients and Review of the Literature

Degirmentepe EN, Kızıltac K, Etikan P, Singer R, Memet B, Kocaturk E

Urticarial vasculitis is an eruption characterized by inflamed itchy or painful red papules or plaques that resemble urticaria but last longer than 24 hours and heal with residual pigmentation or...
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Influence of Intranasal Drugs on Human Nasal Mucociliary Clearance and Ciliary Beat Frequency

Jiao J, Zhang L

The nasal mucociliary clearance system, which comprises epithelial cilia and mucus from goblet cells, is an important intrinsic defense mechanism of the upper respiratory tract. Intranasal drugs and additives can...
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Drug eruption by antihistamine mistaken for chronic urticaria in a child

Lee GM, Chu SY, Kang SY, Kim HB, Park JS, Kim JK

Although rare, antihistamines can cause adverse effects, including drug-induced eruptions or anaphylaxis. A 4-year-old child visited the pediatric department of a hospital for skin eruptions after administration of antihistamines, (e.g.,...
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Urticaria Multiforme with Residual Pigmentation: Two Case Reports

Roh D, Kim WI, Yang MY, Lee WK, Kim TW, Park SM, Lee HJ, Kim GW, Kim HS, Kim BS, Kim MB, Ko HC

  • KMID: 2433642
  • Korean J Dermatol.
  • 2019 Jan;57(1):32-35.
Urticaria multiforme is a cutaneous condition observed in children. This self-limited condition is characterized by well-circumscribed, annular, and erythematous wheals, which spontaneously disappear within a few days. Patients commonly present...
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Updated treatment guideline of chronic spontaneous urticaria

Roh JY

Chronic spontaneous urticaria (CSU), also known as chronic idiopathic urticaria, is a common chronic inflammatory skin disorder that has a prevalence of 0.5% to 1% in the general population. It...
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Treatment of Severe Pregnancy Rhinitis Using Microdebrider-Assisted Inferior Turbinoplasty: A Case Report

Shin DB, Lee JO, Chun TU, Lee TH

Pregnancy rhinitis is a relatively common condition. It is characterized by the presence of nasal symptoms, especially nasal congestion, not present prior to pregnancy, but typically present during the last...
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Pathophysiology and new treatment of itch

Jung MJ, Choi YW, Chung BY, Park CW, Kim HO

Many of the patients visit the doctors because of itching sensation. Itching is an unpleasant sensation. In the epidermal keratinocytes, various neurotransmitters and receptors are related itching. The itch signal...
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Development of a Consensus List of Potentially Inappropriate Medications for Korean Older Adults

Kim MY, Etherton-Beer C, Kim CB, Yoon JL, Ga H, Kim HC, Song JS, Kim KI, Won CW

BACKGROUND: Korea has recently attained the aged society status and the growth rate of the aging population will be among the most rapid worldwide. The objective of this study was...
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Age group characteristics of children who visited the emergency department with acute poisoning by ingestion

Ryu WS, Choi JY, Cho JS, Lim YS, Hyun SY, Yang HJ

PURPOSE: To investigate the age group characteristics of children who visited the emergency department with acute poisoning by ingestion. METHODS: We reviewed children under 19 years who visited the emergency department...
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The Efficacy and Safety of Continuous Intravenous Infusion of Low-dose Epinephrine in Patients with Severe Acute Urticaria Who Do Not Achieve Sufficient Responses to Conventional Treatments: An 8-year Retrospective Study

Jeong WS, Hwangbo H, Lee SK

  • KMID: 2436684
  • Korean J Dermatol.
  • 2018 May;56(4):242-250.
BACKGROUND: Acute urticaria sometimes accompanies severe systemic reactions that can be potentially life-threatening. Some patients do not achieve sufficient responses to conventional treatments. There has been no previous study on...
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Intensely Pruritic Papules and Plaques in Waldenstrom's Macroglobulinemia

Lee S, Lee NR, Choe SJ, Kim BJ, Eom M, Choi EH

Waldenstrom's macroglobulinemia (WM) is lymphoplasmacytoid malignancy that affects B lymphocytes. Cutaneous involvement of WM is rare, but various cutaneous manifestations have been reported. These findings are due to various pathological...
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Misunderstandings and Truth about Chronic Cough

Jang SH

There seem to be several pitfalls in an anatomic, diagnostic protocol for the evaluation of chronic cough. Instead, it is reasonable to propose that non-asthmatic chronic cough depends on the...
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Chronic Spontaneous Urticaria: Pathogenesis and Treatment Considerations

Kaplan AP

The treatment of chronic spontaneous urticaria begins with antihistamines; however, the dose required typically exceeds that recommended for allergic rhinitis. Second-generation, relatively non-sedating H1-receptor blockers are typically employed up to...
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Comparison of the Hospital-Acquired Clostridium difficile Infection Risk of Using Proton Pump Inhibitors versus Histamine-2 Receptor Antagonists for Prophylaxis and Treatment of Stress Ulcers: A Systematic Review and Meta-Analysis

Azab M, Doo L, Doo DH, Elmofti Y, Ahmed M, Cadavona J, Liu XB, Shafi A, Joo MK, Yoo JW

BACKGROUND/AIMS: Although proton pump inhibitors (PPIs) have been widely used for the prevention and treatment of stress gastric ulcers in hospital settings, there are concerns that PPIs increase the risk...
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Current clinical application of dexmedetomidine for sedation and anesthesia

Kim DS, Na HS, Lee JH, Shin YD, Shim JK, Shin HW, Kang H, Joung KW

Many sedatives are used clinically and include benzodiazepines, barbiturates, antihistamines, propofol, and alpha-2-agonist. Benzodiazepines activate GABA neuronal receptors in the brain and present sedating, hypnotic, anxiolytic, amnestic, and anticonvulsant effects,...
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Clinical Practice Guideline for Physicians on Allergic Rhinitis

Koh YI

Recently, the rhinitis work group of the Korean Academy of Asthma, Allergy and Clinical Immunology developed a practice guideline on allergic rhinitis. The group consisted of physicians, pediatricians, and otolaryngologists....
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