- Expression of Hepatitis C Virus Core Protein in Hepatocytes Does Not Modulate Proliferation or Apoptosis of CD8+ T Cells
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Jin YH, Crispe IN, Park S
- KMID: 2428300
- Yonsei Med J.
- 2005 Dec;46(6):827-834.
Hepatocytes are the primary targets of the hepatitis C virus (HCV). While immunosuppressive roles of HCV core protein have been found in several studies, it remains uncertain whether core protein... -
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- Hepatocyte Expressions in Hepatocellular Carcinomas, Gastrointestinal Neoplasms, and Non-neoplastic Gastrointestinal Mucosa: its Role as a Diagnostic Marker
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Lee HS, Kim WH, Kang GH
- KMID: 1086741
- J Korean Med Sci.
- 2003 Dec;18(6):842-848.
- doi: 10.3346/jkms.2003.18.6.842
We performed immunohistochemical staining against Hepatocyte (Hep) and CD10 antibodies in 75 hepatocellular carcinoma (HCC), 50 cholangiocarcinomas, 49 colorectal adenocarcinomas, and 308 gastric adenocarcinomas by tissue array method. We also... -
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- Therapeutic Effects of Mesenchymal Stem Cells for Patients with Chronic Liver Diseases: Systematic Review and Meta-analysis
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Kim G, Eom YW, Baik SK, Shin Y, Lim YL, Kim MY, Kwon SO, Chang SJ
- KMID: 2344172
- J Korean Med Sci.
- 2015 Oct;30(10):1405-1415.
- doi: 10.3346/jkms.2015.30.10.1405
Based on their ability to differentiate into multiple cell types including hepatocytes, the transplantation of mesenchymal stem cells (MSCs) has been suggested as an effective therapy for chronic liver diseases.... -
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- Decreased C-reactive protein induces abnormal vascular structure in a rat model of liver dysfunction induced by bile duct ligation
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Jun JH, Choi JH, Bae SH, Oh SH, Kim GJ
- KMID: 2373138
- Clin Mol Hepatol.
- 2016 Sep;22(3):372-381.
- doi: 10.3350/cmh.2016.0032
BACKGROUND/AIMS: Chronic liver disease leads to liver fibrosis, and although the liver does have a certain regenerative capacity, this disease is associated with dysfunction of the liver vessels. C-reactive protein... -
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- Characterization of cis-acting elements in the rat ATP citrate-lyase gene promoter
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Moon YA, Park SW, Kim KS
- KMID: 1093599
- Exp Mol Med.
- 2002 Mar;34(1):60-68.
The cis-acting element in the promoter of the rat ATP-citrate lyase (ACL) and transcription factors which interact with these elements were determined. Six Sp1 binding sites and CAAT box exist... -
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- Differential Thioredoxin Reductase Activity from Human Normal Hepatic and Hepatoma Cell Lines
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Jung HI, Lim HW, Kim BC, Park EH, Lim CJ
- KMID: 2428322
- Yonsei Med J.
- 2004 Apr;45(2):263-272.
Thioredoxin reductase (TrxR), a component of the thioredoxin system, including thioredoxin (Trx) and NADPH, catalyzes the transfer of electrons from NADPH to Trx, acts as a reductant of disulfide-containing proteins... -
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- In vivo alternative testing with zebrafish in ecotoxicology
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Seok SH, Baek MW, Lee HY, Kim DJ, Na YR, Noh KJ, Park SH, Lee HK, Lee BH, Park JH
- KMID: 1104909
- J Vet Sci.
- 2008 Dec;9(4):351-357.
- doi: 10.4142/jvs.2008.9.4.351
Although rodents have previously been used in ecotoxicological studies, they are expensive, time-consuming, and are limited by strict legal restrictions. The present study used a zebrafish (Danio rerio) model and... -
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- Characteristics of Potassium and Calcium Currents of Hepatic Stellate Cells (Ito) in Rat
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Lee KI, Kong ID, Baik SK, Kim HS, Lee DK, Kwon SO, Chun BG
- KMID: 721416
- Yonsei Med J.
- 2004 Aug;45(4):649-660.
- doi: 10.3349/ymj.2004.45.4.649
Hepatic stellate cells (HSCs) are known to play a role in the pathogenesis of the increased intrahepatic vascular resistance found in chronic liver diseases. The aim of this study was... -
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- Gap junction blockage promotes cadmium-induced apoptosis in BRL 3A derived from Buffalo rat liver cells
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Hu D, Zou H, Han T, Xie J, Dai N, Zhuo L, Gu J, Bian J, Yuan Y, Liu X, Liu Z
- KMID: 2363336
- J Vet Sci.
- 2016 Mar;17(1):63-70.
- doi: 10.4142/jvs.2016.17.1.63
Gap junctions mediate direct communication between cells; however, toxicological cascade triggered by nonessential metals can abrogate cellular signaling mediated by gap junctions. Although cadmium (Cd) is known to induce apoptosis... -
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