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A successful application of adult polymyxin B-immobilized fiber column hemoperfusion to a neonate with septic shock

Kim YA, Kim H, Kim YM, Park SE

Direct hemoperfusion therapy with a polymyxin B-immobilized fiber column (PMX-HP) has been introduced as a therapeutic option for gram negative bacterial septic shock in adults. However, its use in neonates...
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Methidathion Poisoning

Kim KH, Kim SH, Her C

Although methidathion is an organophosphate insecticide, it is different from the other organophosphates in terms of toxicity. Because of its relatively high fat solubility, the apparent volume of methidathion distribution...
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Acute Kidney Injury after Intravenous Injection of an Organophosphate Compound

Lee JY, Sung WY, Lee IY, Seo SW, Lee WS

Poisoning may result from self-injection. Previous reports have described acute cholinergic crisis, intermediate syndrome, and delayed toxicity resulting from parenteral organophosphate administration. These complications have been managed with antidotal and...
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Use of Polymyxin B Hemoperfusion in a Patient with Septic Shock and Septic Cardiomyopathy Who Was Placed on Extracorporeal Membrane Oxygen Support

Shin SH, Lee H, Choi AJ, Chang KH, Suh GY, Chung CR

Although shock in sepsis is usually managed successfully by conventional medical treatment, a subset of cases do not respond and may require salvage therapies such as veno-arterial extracorporeal membrane oxygenation...
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Refractory Septic Shock Treated with Nephrectomy under the Support of Extracorporeal Membrane Oxygenation

Lee YK, Ryu JA, Yang JH, Park CM, Suh GY, Jeon K, Chung CR

Conventional medical therapies have not been very successful in treating adults with refractory septic shock. The effects of direct hemoperfusion using polymyxin B and veno-arterial extracorporeal membrane oxygenation (ECMO) for...
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Polymyxin B Hemoperfusion in Pneumonic Septic Shock Caused by Gram-Negative Bacteria

Yoo JW, Park SY, Jeon J, Huh JW, Lim CM, Koh Y, Hong SB

Severe sepsis and septic shock are the main causes of death in critically ill patients. Early detection and appropriate treatment according to guidelines are crucial for achieving favorable outcomes. Endotoxin...
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Polymyxin B Immobilized Fiber Hemoperfusion in Refractory Intra-abdominal Septic Shock

Chang HW, Cho YJ, Park SH, Kim M

The effects of direct hemoperfusion with polymyxin B immobilized fiber (PMX) treatment for septic shock have been recently reported. However, little evidence of a true benefit on clinical outcomes, including...
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A Case of Life-Threatening Supraventricular Tachycardia Related to Flecainide Toxicity

Cheon SS, Song JH, Bae MH, Lee JH, Yang DH, Park HS, Chae SC

  • KMID: 2269266
  • Korean J Med.
  • 2014 Jul;87(1):72-76.
Flecainide acetate is a potent class Ic anti-arrhythmic drug with a major sodium channel-blocking effect. Flecainide toxicity can cause myocardial impairment and precipitate circulatory collapse, particularly in patients with renal...
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Diagnostic and Therapeutic Approach for Acute Paraquat Intoxication

Gil HW, Hong JR, Jang SH, Hong SY

Paraquat (PQ) has known negative human health effects, but continues to be commonly used worldwide as a herbicide. Our clinical data shows that the main prognostic factor is the time...
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Successful Management of Fatal Paraquat Poisoning with Four Courses of Steroid and Cyclophosphamide Pulse

Kim KL, Lee CS, Lee MJ, Kim HS, Choi MJ, Yoon JW, Koo JR

  • KMID: 2263461
  • Korean J Med.
  • 2012 Sep;83(3):373-377.
Although severe paraquat poisoning is fatal, intensive immunosuppression can be successful in selected patients. We report the case of a 33-yr-old patient who was poisoned by paraquat and developed multi-organ...
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A Case of Carbol Fuchsin Poisoning Successfully Treated with Hemoperfusion and Continuous Venovenous Hemodiafiltration

Hwang EJ, Kook WJ, Lee SR, Moon JY, Jeong KW, Lee SH, Ihm CG, Lee TW

  • KMID: 2252655
  • Korean J Nephrol.
  • 2011 Sep;30(5):565-569.
Carbol fuchsin is a mixture of phenol and basics fuchsin, used in bacterial staining procedures. It is a component of Ziehl-Neelsen stain. Phenol in Carbol fuchsin is a toxic agent...
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Corrosive Injury Due to Edible Vinegar

Kim DH, Lee SW, Namgung I, Park JH, Kim SJ, Hong YS

  • KMID: 2203638
  • J Korean Soc Clin Toxicol.
  • 2011 Jun;9(1):34-38.
Vinegar is a very popular ingredient used in many cuisines. It is also known for its beneficial health, beauty and possible weight-loss properties. The authors report on a patient who...
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A Case of Acute Renal Failure Induced by Acetaminophen Intoxication

Lee JY, Gil HW, Yang JO, Lee EY, Hong SY

  • KMID: 2259005
  • Korean J Med.
  • 2011 Mar;80(3):348-351.
Acetaminophen is a widely used analgesic and antipyretic. Acetaminophen-induced kidney injury is poorly described. Hepatorenal syndrome, prerenal failure, and direct toxicity of acetaminophen metabolites could be involved in the development...
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Usefulness of Hemoperfusion in Paraquat Poisoning

Choi WS, Jung EH, Park EH, Seo JY, Jun KH, Kang MS, Kim H

  • KMID: 2258998
  • Korean J Med.
  • 2011 Mar;80(3):308-316.
BACKGROUND/AIMS: Paraquat is a potentially lethal herbicide that induces acute renal failure, hepatic dysfunction, and progressive respiratory failure. This study examined the usefulness of hemoperfusion in paraquat poisoning. METHODS: We reviewed...
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Prognostic Factors and the Effect of Hemoperfusion for Patients with Paraquat Poisoning

Sung AJ, Jang JY

BACKGROUND: Paraquat has been widely used as a non-selective contact herbicide and it may induce damage to many organs. This study aimed to assess the factors that can predict the...
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Clinical Observation of Paraquat Poisoning

Jun KH, Kang MS

  • KMID: 2101616
  • J Korean Soc Clin Toxicol.
  • 2009 Jun;7(1):1-9.
PURPOSE: Paraquat, a globally used herbicide, is highly toxic to human beings. Hence, we reviewed some cases of paraquat poisoning in Korea. METHODS: We analyzed the clinical and laboratory findings of...
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A Case of Successful Management of Paraquat Poisoning with Severe Pulmonary Fibrosis

Min JH, Lee JA, Choi WS, Kim H, Kang MS, Jun KH, Jung WM

  • KMID: 2192634
  • J Korean Soc Emerg Med.
  • 2009 Dec;20(6):732-737.
Paraquat, a potent herbicide, has caused many fatalities through indiscriminate use and suicides. With ingestion of more than one mouthful of 20% paraquat, death is usually caused by pulmonary fibrosis....
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Clinical Experience with Continuous Renal Replacement Therapy as a Method of Extracorporeal Elimination and as performed by Emergency Room Physicians for Patients with Poisoning

Ahn JH, Choi SC, Jung YS, Min YG

  • KMID: 1848455
  • J Korean Soc Clin Toxicol.
  • 2009 Dec;7(2):150-155.
PURPOSE: Extracorporeal elimination of drugs is a critical part of managing poisonings, although the indications and optimal method remain a matter of debate. The aim of this study is to...
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A Case of Successful Hemoperfusion in the Treatment of Acute Severe Clozapine Intoxication

Kim HJ, Kim SJ, Lee KH, Gil HW, Yang JO, Lee EY, Hong SY

  • KMID: 2307175
  • Korean J Nephrol.
  • 2009 Nov;28(6):639-642.
Clozapine, a psychotropic drug commonly used in the treatment of schizophrenia or schizophrenic affective disorders may show side effects such as agranulocytosis, cardiomyositis, cognitive and motor depression in therapeutic doses...
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Comparison between Kidney and Hemoperfusion for Paraquat Elimination

Kang MS, Gil HW, Yang JO, Lee EY, Hong SY

The mortality rate of acute paraquat (PQ) poisoning depends on the PQ concentration in the blood. It has been shown that the kidneys eliminate PQ effectively. However, early renal function...
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