Korean J Med.  2014 Jul;87(1):72-76.

A Case of Life-Threatening Supraventricular Tachycardia Related to Flecainide Toxicity

Affiliations
  • 1Division of Cardiology, Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea. ddhyang@knu.ac.kr

Abstract

Flecainide acetate is a potent class Ic anti-arrhythmic drug with a major sodium channel-blocking effect. Flecainide toxicity can cause myocardial impairment and precipitate circulatory collapse, particularly in patients with renal failure. Electrical and hemodynamic deterioration during flecainide toxicity may not respond to conventional treatments. We report the successful management of flecainide toxicity using extracorporeal membrane oxygenation (ECMO), hemoperfusion, and bicarbonate administration maintaining alkalinity.

Keyword

Flecainide; Hemoperfusion; Extracorporeal membrane oxygenation

MeSH Terms

Extracorporeal Membrane Oxygenation
Flecainide*
Hemodynamics
Hemoperfusion
Humans
Renal Insufficiency
Shock
Sodium
Tachycardia, Supraventricular*
Flecainide
Sodium
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