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Isolation and characterization of a 40 kDa cysteine protease from Gymnophalloides seoi adult worms

Choi MH, Park WJ, Park YK, Chai JY, Lee SH

A 40 kDa cysteine protease was purified from the crude extract of adult worms of Gymnophalloides seoi by two consecutive steps: Sephacryl S-200 HR and DEAE-Sephacel chromatography. Enzyme activities were...
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Purification of a 68-kDa cysteine proteinase from crude extract of Pneumocystis carinii

Choi MH, Chung BS, Chung YB, Yu JR, Cho SR, Hong ST

The present study intended to verify activities of cysteine proteinase of Pneumocystis carinii from rats and to purify the enzyme. In order to exclude the contamination of host-derived enzymes, concentrates...
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Characterization of HC58cDNA, a putative cysteine protease from the parasite Haemonchus contortus

Muleke CI, Ruofeng Y, Lixin X, Yanming S, Xiangrui L

Because of the complexity of the cathepsin B-like (CBL) family, an information on the biological and biochemical characteristics of individual CBL genes is lacking. In this study, we investigated the...
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Degradations of human immunoglobulins and hemoglobin by a 60 kDa cysteine proteinase of Trichomonas vaginalis

Min DY, Hyun KH, Ryu JS, Ahn MH, Cho MH

The present study was undertaken to investigate the role of cysteine proteinase of Trichomonas vaginalis in escaping from host defense mechanism. A cysteine proteinase of T. vaginalis was purified...
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Repeated dose toxicity of alfa-cypermethrin in rats

Manna S, Bhattacharyya D, Mandal TK, Das S

  • KMID: 1099838
  • J Vet Sci.
  • 2004 Sep;5(3):241-245.
The present study was performed to investigate the subacute effect of alpha-cypermethrin (alpha-CP) in rats. Alfacypermethrin a synthetic pyrethroid insecticide, dissolved in dimethyl sulfoxide (DMSO) and oral LD50 was investigated...
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Risk Factors of Transfusion in Anemia of Very Low Birth Weight Infants

Jeon GW, Sin JB

PURPOSE: Anemia of prematurity is frequent in preterm infants, for which red blood cell (RBC) transfusion remains the treatment of choice. In this study, we attempted to evaluate the characteristics...
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N-ras Mutation Detection by Pyrosequencing in Adult Patients with Acute Myeloid Leukemia at a Single Institution

Jeong JH, Park SH, Park MJ, Kim MJ, Kim KH, Park PW, Seo YH, Lee JH, Park J, Hong J, Ahn JY

BACKGROUND: N-ras mutations are one of the most commonly detected abnormalities of myeloid origin. N-ras mutations result in a constitutively active N-ras protein that induces uncontrolled cell proliferation and inhibits...
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Effect of Cancer Symptoms and Fatigue on Chemotherapy-related Cognitive Impairment and Depression in People with Gastrointestinal Cancer

Oh PJ, Lee JR

PURPOSE: The purpose of this study was to test a hypothetical model of chemotherapy-related cognitive impairment (CRCI) and depression in people with gastrointestinal cancer. METHODS: A purposive sample of 198 patients...
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Predictive factors of radiographic progression in ankylosing spondylitis

Kim H, Lee J, Ahn JK, Hwang J, Park EJ, Jeong H, Cha HS, Koh EM

BACKGROUND/AIMS: The course of ankylosing spondylitis (AS) is rather variable, and the factors that predict radiographic progression remain largely obscure. In this study, we tried to determine the clinical factors...
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Effect of Fasciola gigantica excretory secretory antigen on rat hematological indices

Ganga G, Varshney J, Sharma RL

The present study was undertaken to investigate the effect of Fasciola gigantica excretory secretory antigen (Fg-ESA) on rat hematological indices. Fg-ESA was prepared by keeping thoroughly washed 40 F. gigantica flukes in 100 ml...
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Effect of anemia correction on left ventricular structure and filling pressure in anemic patients without overt heart disease

Cho IJ, Mun YC, Kwon KH, Shin GJ

  • KMID: 2070108
  • Korean J Intern Med.
  • 2014 Jul;29(4):445-453.
BACKGROUND/AIMS: There are few data on the effects of low hemoglobin levels on the left ventricle (LV) in patients without heart disease. The objective of this study was to document...
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Hematological Aspects of Congenital Syphilis

Kim KY, Kim SH

Hematologic investigations for 7 years at the Pediatric Department of Yonsei Medical Center of 52 syphilitic infants were reviewed. A moderate degree of anemia with red cell regeneration was observed...
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Molecular and biochemical characterization of hemoglobinase, a cysteine proteinase, in Paragonimus westermani

Choi JH, Lee JH, Yu HS, Jeong HJ, Kim J, Hong YC, Kong HH, Chung DI

The mammalian trematode Paragonimus westermani is a typical digenetic parasite, which can cause paragonimiasis in humans. Host tissues and blood cells are important sources of nutrients for development, growth and...
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Decreased Renal Function Is an Independent Predictor of Severity of Coronary Artery Disease: An Application of Gensini Score

Kim IY, Hwang IH, Lee KN, Lee DW, Lee SB, Shin MJ, Rhee H, Yang B, Song SH, Seong EY, Kwak IS

Coronary artery disease (CAD) is the leading cause of death in patients with chronic kidney disease (CKD).Although many studies have shown a higher prevalence of CAD among these patients, the...
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Administration of a High-Dose Erythropoietin-Stimulating Agent in Hemodialysis Patients is Associated with Late Arteriovenous Fistula Failure

Jeong HY, Ko EJ, Kim SH, Lee MJ, Cho HJ, Yang DH, Lee SY

PURPOSE: Investigating the risk of vascular access failure is critical for maintenance hemodialysis (MHD) patients. Erythropoietin stimulating agents (ESA) typically used for anemia of chronic kidney disease (CKD) may also...
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The Relation Between Hypoalbuminemia and Compliance and Intima-media Thickness of Carotid Artery in Continuous Ambulatory Peritoneal Dialysis Patients

Oh DJ, Lee KJ

The aim of this study was to identify the main factor affecting compliance and intima-media thickness of the elastic common carotid artery in continuous ambulatory peritoneal dialysis patients. Increased intima-media...
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Correlations between Janus Kinase 2 V617F Allele Burdens and Clinicohematologic Parameters in Myeloproliferative Neoplasms

Ha JS, Kim YK, Jung SI, Jung HR, Chung IS

  • KMID: 2434478
  • Ann Lab Med.
  • 2012 Nov;32(6):385-391.
BACKGROUND: This study evaluated potential correlations between the allele burden of the Janus kinase 2 (JAK2) V617F mutation and clinicohematologic characteristics in patients with myeloproliferative neoplasms (MPN). METHODS: Clinical and hematologic...
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A Comprehensive Analysis of the Causes and Predictors of 30-Day Mortality Following Hip Fracture Surgery

Sheikh HQ, Hossain FS, Aqil A, Akinbamijo B, Mushtaq V, Kapoor H

BACKGROUND: A fracture neck of femur is the leading cause of injury-related mortality in the elderly population. The 30-day mortality figure is a well utilised marker of clinical outcome following...
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Survival Outcomes of Concurrent Treatment with Docetaxel and Androgen Deprivation Therapy in Metastatic Castration-Resistant Prostate Cancer

Jang HS, Koo KC, Cho KS, Chung BH

PURPOSE: Docetaxel-based chemotherapy (DTX) improves overall survival (OS) of men with metastatic castration-resistant prostate cancer (mCRPC). Considering the potential existence of androgen receptors that remain active at this stage, we...
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Clinical Investigation of Cavitary Tuberculosis and Tuberculous Pneumonia

Lee KM, Choe KH, Kim SJ

BACKGROUND: The radiographic characteristics of tuberculous pneumonia in adults are similar to primary tuberculosis that occurs in childhood, and upper lobe cavitary tuberculosis is the hallmark of postprimary tuberculosis....
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