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The Prognostic Impact of Heat Shock Proteins Expression in Patients with Esophageal Cancer: A Meta-Analysis

Wang XW, Shi XH, Tong YS, Cao XF

PURPOSE: Heat shock proteins (HSPs) are highly conserved molecular chaperones. There are various studies that assess the prognostic value of HSPs in patients with esophageal cancer, but the conclusion remains...
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Expressions of HSP70 and HSP27 in Hepatocellular Carcinoma

Joo M, Chi JG, Lee H

The heat shock proteins (HSPs) are ubiquitous molecules induced in cells exposed to various stress conditions, including carcinogenesis. The HSP70 and HSP27 among HSPs are of special relevance in human...
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Heat Shock Protein Expression in Adenosine Triphosphate Depleted Renal Epithelial Cells

Oh DJ, Yu SH, Kang ET

  • KMID: 1115224
  • Korean J Intern Med.
  • 2004 Sep;19(3):149-154.
BACKGROUND: In this study, the putative interactions between apoptosis and heat shock proteins disturbed as a result of ATP depletion were investigated as a hypoxia model. METHODS: The direct cellular...
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The expressions of HSP70 and alphaB-crystallin in myocarditis associated with foot-and-mouth disease virus in lambs

Gulbahar M, Kabak YB, Karayigit , Yarim M, Guvenc T, Parlak U

This study describes the expression of heat shock protein70 (HSP70) and alpha-basic-crystallin (alpha-BC) and their association with apoptosis and some related adaptor proteins in the pathogenesis of foot-and-mouth disease virus...
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Expression of Heat Shock Protein 70 Modulates the Chemoresponsiveness of Pancreatic Cancer

Hyun JJ, Lee HS, Keum B, Seo YS, Jeen YT, Chun HJ, Um SH, Kim CD

  • KMID: 1712336
  • Gut Liver.
  • 2013 Nov;7(6):739-746.
BACKGROUND/AIMS: Heat shock protein (HSP) 70 is constitutively overexpressed in pancreatic cancer cells (PCCs) and appears to confer protection against chemotherapeutics. We investigated whether modulating HSP 70 increases chemoresponsiveness to...
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Expression levels of heat shock protein 27 and cellular FLICE-like inhibitory protein in prostate cancer correlate with Gleason score sum and pathologic stage

Lee SW, Cho JM, Cho HJ, Kang JY, Kim EK, Yoo TK

PURPOSE: Heat shock protein (HSP) 27 protects the cell by controlling apoptosis and immune reactions, and c-FLIP (cellular-FLICE inhibitory protein) inhibits apoptosis by inhibiting caspase-8 activity. We investigated the relationship...
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Hsp70 and HSF-1 expression is altered in the tissues of pigs transported for various periods of times

Zhang M, Yue Z, Liu Z, Islam A, Rehana B, Tang S, Bao E, Hartung J

The aim of this study was to assess changes of Hsp70 and HSF-1 protein and mRNA expression in stress-sensitive organs of pigs during transportation for various periods of time. Twenty...
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Expression of CAIII and Hsp70 Is Increased the Mucous Membrane of the Posterior Commissure in Laryngopharyngeal Reflux Disease

Min HJ, Hong SC, Yang HS, Mun SK, Lee SY

PURPOSE: We tried to evaluate the difference in the expression of carbonic anhydrase (CA) III and heat shock protein (Hsp) 70 between laryngopharyngeal reflux disease (LPRD) and non-LPRD patients. MATERIALS AND...
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Effects of Benzo(a)pyrene on the Expression of Heat Shock Proteins, Pro-inflammatory Cytokines and Antioxidant Enzymes in Hepatic Tumors Induced by Rat Hepatoma N1-S1 Cells

Zheng Z, Park SY, Lee M, Phark S, Won NH, Kang HS, Sul D

Benzo(a)pyrene (BaP) is a polycyclic aromatic hydrocarbon (PAH) that is easily introduced to humans via consumption of grilled or smoked meat. BaP causes harmful oxidative effects on cell development, growth...
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Heat shock protein 27 interacts with vimentin and prevents insolubilization of vimentin subunits induced by cadmium

Lee JS, Zhang MH, Yun EK, Geum D, Kim K, Kim TH, Lim YS, Seo JS

  • KMID: 1089452
  • Exp Mol Med.
  • 2005 Oct;37(5):427-435.
Vimentin is an intermediate filament that regulates cell attachment and subcellular organization. In this study, vimentin filaments were morphologically altered, and its soluble subunits were rapidly reduced via cadmium chloride...
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Transcription repression of a CCAAT-binding transcription factor CBF/HSP70 by p53

Chae HD, Yun J, Shi D

  • KMID: 1089459
  • Exp Mol Med.
  • 2005 Oct;37(5):488-491.
NF-Y transcription factor binds to CCAAT boxes on promoters of cell cycle regulatory genes such as cdc2, cyclin B, cdc25C, and cyclin A. We previously reported that the DNA binding...
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