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Echocardiographic Evaluation of Axial Spondyloarthritis in Korea: Data From the Catholic Axial Spondyloarthritis Cohort

Min HK, Lee J, Ju JH, Kwok SK, Youn HJ, Park SH

OBJECTIVE: Axial spondyloarthritis (axSpA) is often accompanied by cardiac manifestations, such as valvular heart disease. In this prospective cohort study, we evaluated the incidence of cardiac abnormalities in Korean axSpA...
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Annual Report of Korean Association of External Quality Assessment Service on Histocompatibility Testing (2018)

Kang ES

Here, we report the results of the first histocompatibility proficiency testing (PT) performed by the Korean Association of External Quality Assessment Service in 2018. The directly prepared PT specimens of...
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A Variant in RUNX3 Is Associated with the Risk of Ankylosing Spondylitis in Koreans

Cho SM, Jung SH, Chung YJ

Ankylosing spondylitis (AS) is a chronic autoinflammatory disease that affects the spine and sacroiliac joints. Regarding its etiology, although HLA-B27 is known to be the strongest genetic factor of AS,...
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Recurrent macrophage activation syndrome since toddler age in an adolescent boy with HLA B27 positive juvenile ankylosing spondylitis

Park JH, Seo YM, Han SB, Kim KH, Rhim JW, Chung NG, Kim MS, Kang JH, Jeong DC

Recurrent macrophage activation syndrome (MAS) is very rare. We present the case of an adolescent boy with human leukocyte antigen (HLA) B27-positive ankylosing spondylitis (AS), who experienced episodes of recurrent...
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Human Leukocyte Antigen B27 and Juvenile Idiopathic Arthritis and Classification of Juvenile Spondyloarthropathies by the Assessment of SpondyloArthritis International Society Criteria

Eom SN, Seo AD, Kim KN

OBJECTIVE: We examined the clinical relationship between human leukocyte antigen B27 (HLA-B27) and juvenile idiopathic arthritis (JIA). Additionally, we assessed the usefulness of the Assessment of SpondyloArthritis International Society (ASAS)...
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Phenotype Difference between Familial and Sporadic Ankylosing Spondylitis in Korean Patients

Kim HW, Choe HR, Lee SB, Chang WI, Chae HJ, Moon JY, Kang J, Lee S, Song YW, Lee EY

Clustered occurrences of ankylosing spondylitis (AS) in family have been noticed. We evaluated patients with AS confirmed by the modified New York criteria for familial history of AS (one or...
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A Case of Acute Anterior Uveitis Associated with HLA-B27 Positivity after Intravitreal Injection of Bevacizumab

Seo JW, Kwon YH

  • KMID: 2338579
  • J Korean Ophthalmol Soc.
  • 2013 Dec;54(12):1945-1949.
PURPOSE: Intravitreal injection of bevacizumab (Avastin(R)) can lead to several intraocular complications including endophthalmitis, hemorrhage and inflammation. We present one case of acute anterior uveitis with hypopyon in an HLA-B27(+)...
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Reactive Arthritis

Park KS

Reactive arthritis (ReA) is an inflammatory joint disease following genitourinary or gastrointestinal bacterial infection, most commonly by Chlamydia trachomatis. It is characterized by the inflammation in the large joints of...
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Clinical Manifestation and Diagnosis of Ankylosing Spondylitis

Shin K

Ankylosing spondylitis (AS) is the main disease entity within spondyloarthritides. AS patients can present with both articular and extra-articular manifestations. Especially, inflammatory back pain has been recognized as the main...
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The Concept and Overview of Spondyloarthritis

Seo MR, Baek HJ

The spondyloarthritis (SpA) is a group of chronic inflammatory rheumatic diseases in association with HLA-B27. They share the clinical features including sacroiliitis, spondylitis, oligoarthritis, enthesitis and extra-articular involvement. Recently ASAS...
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Flow Cytometric Human Leukocyte Antigen-B27 Typing with Stored Samples for Batch Testing

Seo BY, Won DI

BACKGROUND: Flow cytometry (FC) HLA-B27 typing is still used extensively for the diagnosis of spondyloarthropathies. If patient blood samples are stored for a prolonged duration, this testing can be performed...
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New concepts in systemic rheumatic diseases that are registered as rare diseases in Korea

Lee JJ, Park SH

This new classification system redefines the current paradigm of rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and ankylosing spondylitis (AS), by focusing on the features of the disease at earlier...
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A Case of Ankylosing Spondylitis with Follicular Lymphoma

Park HJ, Park YH, Park KH, Kim M, Choe EY, Han JW, Hong JY, Chang MH, Kim SJ, Shim JE, Kie JH, Lee SW, Park YB, Lee SK, Lee CH

Several autoimmune and chronic inflammatory conditions have been consistently linked with an increased risk of hematologic malignancies. Although ankylosing spondylitis (AS) is a chronic inflammatory disease, previous studies have demonstrated...
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Uveitis and Rheumatic Diseases in a Community Based Practice - Korean Population

Kim NK, Park MY, Lee JH, Lee DH, Yoon BY

OBJECTIVE: We aimed to investigate the frequency of rheumatic diseases within uveitis patients visiting the department of Ophthalmology and evaluated the clinical value of serological testing and ophthalmologic findings in...
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A case of reactive arthritis after Salmonella enteritis in in a 12-year-old boy

Chun P, Kim YJ, Han YM, Kim YM

Reactive arthritis comprises a subgroup within infection-associated arthritides in genetically susceptible hosts. Researchers and clinicians recognize two clinical forms of reactive arthritis which occurs after genitourinary tract infection and after...
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Determining Clinical Risk Factors for Radiographical Severity in Patients with Ankylosing Spondylitis in Daegu and Kyungpook Territories

Jung HY, Lee HJ, Choe JY, Park SH, Kim SK, Kim SH, Kim J, Han SW, Kim SH

OBJECTIVE: This study was designed to identify prognostic determinants of radiographical severity in patients with ankylosing spondylitis (AS) living in Daegu and Kyungpook territories. METHODS: One hundred-nineteen patients with AS were...
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Clinical and Radiographic Features of Adult-onset Ankylosing Spondylitis in Korean Patients: Comparisons between Males and Females

Jung YO, Kim I, Kim S, Suh CH, Park HJ, Park W, Kwon SR, Jeong JC, Lee YJ, Ryu HJ, Park YB, Lee J, Lee YH, Seo YI, Chung WT, Hong SJ, Hong YS, Baek HJ, Choi HJ, Kang HJ, Lee CH, Kim SH, Kim HA

The objective of this study was to investigate clinical and radiographic features and gender differences in Korean patients with adult-onset ankylosing spondylitis. Multicenter cross-sectional studies were conducted in the rheumatology...
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Treatment of Late Onset Ankylosing Spondylitis with TNF Antagonist: A Case Series

Lee JS, Bang SY, Yoo DH, Byun YS, Park SY, Kim TH

Ankylosing spondylitis is a disease that shows a young age of onset (less than 40 years old), inflammatory back pain, sacroiliitis and a strong association with HLA-B27. Yet some recently...
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Evaluation of Two Commercial HLA-B27 Real-Time PCR Kits

Cho EH, Lee SG, Seok JH, Park BY, Lee EH

BACKGROUND: The standard PCR with sequence-specific primers (SSP) is a widely used method of HLA-B27 typing in clinical practice. The aim of our study was to evaluate 2 Korean HLA-B27...
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Clinical Features and Prognosis of HLA-B27 Positive and Negative Anterior Uveitis in a Korean Population

Park SC, Ham DI

Clinical features and prognosis of HLA-B27 positive anterior uveitis (AU) were assessed compared with HLA-B27 negative AU in a Korean population, based on the medical records of AU patients seen...
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