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Do Esophageal Squamous Cell Carcinoma Patients Have an Increased Risk of Coexisting Colorectal Neoplasms?

Jang BI, Hwang MJ

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Proton Pump Inhibitor-Responsive Esophageal Eosinophilia: Controversies and Its Clinical Implications

Shin CM, Lee DH

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Changes in Hospital Admissions and Mortality for Complications of Cirrhosis: Implications for Clinicians and Health Systems

Ho SB, Matheny ME, Schnabl BE

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Reappraisal of Antihypertensive Medicine Doxazosin and Carvedilol as a Potential Therapeutic for Hepatic Fibrosis

Paik YH

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Understanding the Role of Endoscopic Ultrasonography in Early Gastric Cancer

Park CH, Lee SK

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Drug-Induced Liver Injury: Pattern Recognition and Future Directions

Haque T, Sasatomi E, Hayashi PH

Drug-induced liver injury (DILI) remains a significant clinical challenge and is the leading cause of acute liver failure in most countries. An aging population that uses more medications, a constant...
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Prevalence and Factors Associated with Nonalcoholic Fatty Liver Disease in a Nonobese Korean Population

Cho HC

BACKGROUND/AIMS: Nonalcoholic fatty liver disease (NAFLD) is an emerging problem in Asia, but little is known about the disease in the nonobese population. The aims of this study were to...
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Esophageal Mast Cell Infiltration in a 32-Year-Old Woman with Noncardiac Chest Pain

Lee K, Kwon HJ, Kim IY, Yoo KH, Lee S, Min YW, Rhee PL

Noncardiac chest pain (NCCP) is one of the most common esophageal symptoms and lacks a clearly defined mechanism. The most common cause of NCCP is gastroesophageal reflux disease (GERD). One...
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Effects of Surgical Methods and Tumor Location on Survival and Recurrence Patterns after Curative Resection in Patients with T2 Gallbladder Cancer

Jung W, Jang JY, Kang MJ, Chang YR, Shin YC, Chang J, Kim SW

BACKGROUND/AIMS: Extended cholecystectomy is generally recommended for patients with T2 gallbladder cancer. However, few studies have assessed the extent of resection relative to T2 gallbladder tumor location. This study analyzed...
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Clinical Implications of the Serum Apelin Level on Portal Hypertension and Prognosis of Liver Cirrhosis

Lim YL, Choi E, Jang YO, Cho YZ, Kang YS, Baik SK, Kwon SO, Kim MY

BACKGROUND/AIMS: Levels of serum apelin (s-apelin), an endogenous ligand for angiotensin-like receptor 1, have been shown to be related to hepatic fibrosis and hemodynamic abnormalities in preclinical studies. We investigated...
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Complications Requiring Hospital Admission and Causes of In-Hospital Death over Time in Alcoholic and Nonalcoholic Cirrhosis Patients

Kim HY, Kim CW, Choi JY, Lee CD, Lee SH, Kim MY, Jang BK, Woo HY

BACKGROUND/AIMS: Data on the epidemiology of alcoholic cirrhosis, especially in Asian countries, are limited. We compared the temporal evolution of patterns of alcoholic and nonalcoholic cirrhosis over the last decade. METHODS:...
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Mass Eradication of Helicobacter pylori to Prevent Gastric Cancer: Theoretical and Practical Considerations

Lee YC, Chiang TH, Liou JM, Chen HH, Wu MS, Graham DY

Although the age-adjusted incidence of gastric cancer is declining, the absolute number of new cases of gastric cancer is increasing due to population growth and aging. An effective strategy is...
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Endoscopic Findings of Enteropathy-Associated T-Cell Lymphoma Type II: A Case Series

Hong YS, Woo YS, Park G, Lee K, Kang SH, Lee HW, Kim ER, Hong SN, Chang DK, Kim YH, Rhee PL, Kim JJ

Enteropathy-associated T-cell lymphoma (EATL) is a rare extranodal T-cell lymphoma arising from the intestine. Two types of EATL have been reported. In contrast to the classic EATL type I, EATL...
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Doxazosin Treatment Attenuates Carbon Tetrachloride-Induced Liver Fibrosis in Hamsters through a Decrease in Transforming Growth Factor beta Secretion

Munoz-Ortega MH, Llamas-Ramirez RW, Romero-Delgadillo NI, Elias-Flores TG, de Jesus Tavares-Rodriguez E, del Rosario Campos-Esparza M, Cervantes-Garcia D, Munoz-Fernandez L, Gerardo-Rodriguez M, Ventura-Juarez J

BACKGROUND/AIMS: The development of therapeutic strategies for the treatment of cirrhosis has become an important focus for basic and clinical researchers. Adrenergic receptor antagonists have been evaluated as antifibrotic drugs...
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Negative Biopsy after Referral for Biopsy-Proven Gastric Cancer

Tae CH, Lee JH, Min BH, Kim KM, Rhee PL, Kim JJ

BACKGROUND/AIMS: Repeat endoscopy with biopsy is often performed in patients with previously diagnosed gastric cancer to determine further treatment plans. However, biopsy results may differ from the original pathologic report....
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Therapeutic Decision-Making Using Endoscopic Ultrasonography in Endoscopic Treatment of Early Gastric Cancer

Lee JY, Choi IJ, Kim CG, Cho SJ, Kook MC, Ryu KW, Kim YW

BACKGROUND/AIMS: We evaluated the effectiveness of an endoscopic ultrasonography (EUS)-based treatment plan compared to an endoscopy-based treatment plan in selecting candidates with early gastric cancer (EGC) for endoscopic submucosal dissection...
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Assessment of Factors Affecting the Usefulness and Diagnostic Yield of Core Biopsy Needles with a Side Hole in Endoscopic Ultrasound-Guided Fine-Needle Aspiration

Inoue T, Okumura F, Mizushima , Nishie H, Iwasaki H, Anbe K, Ozeki T, Kachi K, Fukusada S, Suzuki Y, Sano H

BACKGROUND/AIMS: A barbed puncture needle with a side hole was recently developed to improve sample quality and quantity in endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA). In this study, we retrospectively assessed...
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Esophageal Squamous Cell Carcinoma Patients Have an Increased Risk of Coexisting Colorectal Neoplasms

Baeg MK, Choi MG, Jung YD, Ko SH, Lim CH, Kim HH, Kim JS, Cho YK, Park JM, Lee IS, Kim SW

BACKGROUND/AIMS: Esophageal squamous cell carcinoma (ESCC) and colorectal neoplasms (CRNs) share risk factors. We aimed to investigate whether the CRN risk is increased in ESCC patients. METHODS: ESCC patients who underwent...
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Clinicopathologic Analysis of Proton Pump Inhibitor-Responsive Esophageal Eosinophilia in Korean Patients

Jung DH, Yun GW, Lee YJ, Jo Y, Park H

BACKGROUND/AIMS: Proton pump inhibitor-responsive esophageal eosinophilia (PPI-REE) is a newly recognized form of eosinophilic esophagitis (EoE) that responds to PPI therapy. It remains unclear whether PPI-REE represents a subphenotype of...
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Clinical Risk Factors for Upper Gastrointestinal Bleeding after Percutaneous Coronary Intervention: A Single-Center Study

Lee JM, Park SY, Choi JH, Kim UJ, Rew SJ, Cho JY, Ahn Y, Lim SW, Jun CH, Park CH, Kim HS, Choi SK, Rew JS

BACKGROUND/AIMS: Percutaneous coronary intervention (PCI) is often performed therapeutically, and antithrombotic treatment is required for at least 12 months after stent implantation. However, the development of post-PCI upper gastrointestinal bleeding...
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