Gut Liver.  2016 Jan;10(1):51-57. 10.5009/gnl14249.

Assessment of Factors Affecting the Usefulness and Diagnostic Yield of Core Biopsy Needles with a Side Hole in Endoscopic Ultrasound-Guided Fine-Needle Aspiration

• Inoue T
• Okumura F
• Mizushima
• Nishie H
• Iwasaki H
• Anbe K
• Ozeki T
• Kachi K
• Fukusada S
• Suzuki Y
• Sano H

• KMID: 2382343
• DOI: http://doi.org/10.5009/gnl14249

Abstract

BACKGROUND/AIMS
A barbed puncture needle with a side hole was recently developed to improve sample quality and quantity in endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA). In this study, we retrospectively assessed the usefulness of this puncture needle.
METHODS
Factors affecting diagnostic yield, safety, and diagnostic accuracy were investigated in 76 patients who consecutively underwent EUS-FNA for neoplastic lesions at our hospital between January and December 2013.
RESULTS
The procedure was successful in all cases; the rates of sample collection and determination of the correct diagnosis were 92.1% and 89.5%, respectively. The mean number of needle passes required for diagnosis was 1.1. Complications included mild intraluminal bleeding in two patients (2.6%). Multivariate analysis revealed that lesion size (< or =20 mm) was significantly associated with a decreased chance of determining the correct diagnosis.
CONCLUSIONS
Core biopsy needles with a side hole are safe and provide a satisfactory diagnostic yield. However, the side hole may potentially reduce the rate of making the correct diagnosis in small lesions.

Keyword

Endoscopic ultrasound-guided fine needle aspiration; Biopsy needles; Side hole; Size of lesions

MeSH Terms

Adult
Aged
Aged, 80 and over
Digestive System Neoplasms/*diagnosis/ultrasonography
Endoscopic Ultrasound-Guided Fine Needle Aspiration/*instrumentation
Equipment Design
Equipment Safety
Female
Gastrointestinal Tract/pathology/ultrasonography
Humans
Male
Middle Aged
Multivariate Analysis
Needles/adverse effects/*statistics & numerical data
Predictive Value of Tests
Retrospective Studies
Sensitivity and Specificity
Statistics, Nonparametric