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Flavonoid Glycosides from the Flowers of Pulsatilla koreana Nakai

Seo KH, Jung JW, Thi NN, Lee YH, Baek NI

Extraction and fractionation of Pulsatilla koreana flowers followed by, repeated open column chromatography for EtOAc and n-BuOH fractions yielded four flavonoid glycosides, namely, astragalin (1), tiliroside (2), buddlenoide A (3),...
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A New Steroidal Glycoside from Allium macrostemon Bunge

Kim YS, Cha JM, Kim DH, Lee TH, Lee KR

A phytochemical investigation of Allium macrostemon Bunge (Liliaceae) afforded the new pregnane steroidal glycoside, named allimacroside F (1), along with three known glycosides, benzyl-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside (2), phenylethyl-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside (3), (Z)-3-hexenyl-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside (4). The...
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Chemical Constituents from the Aerial Parts of Bupleurum falcatum L. and Biological Evidences

Tung NH, Uto T, Morinaga O, Shoyama Y

In this study, phytochemical investigation on the aerial parts of Bupleurum falcatum resulted in the isolation of fourteen compounds including three quinic acid derivatives (1 - 3), five flavonoids (4...
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Differential Effects of Quercetin and Quercetin Glycosides on Human α7 Nicotinic Acetylcholine Receptor-Mediated Ion Currents

Lee BH, Choi SH, Kim HJ, Jung SW, Hwang SH, Pyo MK, Rhim H, Kim HC, Kim HK, Lee SM, Nah SY

Quercetin is a flavonoid usually found in fruits and vegetables. Aside from its antioxidative effects, quercetin, like other flavonoids, has a various neuropharmacological actions. Quercetin-3-O-rhamnoside (Rham1), quercetin-3-O-rutinoside (Rutin), and quercetin-3-(2(G)-rhamnosylrutinoside...
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Isolation of Flavonoid Glycosides with Cholinesterase Inhibition Activity and Quantification from Stachys japonica

Nugroho A, Choi JS, Seong SH, Song BM, Park KS, Park HJ

The three flavone glycosides, 4′-O-methylisoscutellarein 7-O-(6‴-O-acetyl)-β-D-allopyranosyl(1→2)-β-D-glucopyranoside (1), isoscutellarein 7-O-(6‴-O-acetyl)-β-D-allopyranosyl(1→2)-β-D-glucopyranoside (3), and isoscutellarein 7-O-β-D-allopyranosyl(1→2)-β-D-glucopyranoside (4) in addition to a flavonol glycoside, kaempferol 3-O-β-D-glucopyranoside (astragalin, 2), were isolated from Stachys japonica (Lamiaceae)....
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Phenolic Compounds Isolated from Opuntia ficus-indica Fruits

Kim JW, Kim TB, Yang H, Sung SH

On the phytochemical investigation of a 70% ethanol extract of the fruits of Opuntia ficus-indica, (Cacataceae), we could result in the isolation of thirteen phenolic compounds including seven flavonoids (1...
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Gastroprotective Activities of Sennoside A and Sennoside B via the Up-Regulation of Prostaglandin E2 and the Inhibition of H+/K+-ATPase

Hwang IY, Jeong CS

Sennoside A (erythro) and sennoside B (threo) are dianthrone glycosides and diastereomers. We investigated their abilities to prevent the gastric lesions associated with diseases, such as, gastritis and gastric ulcer....
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Identification and HPLC Quantification of a Phytoecdysone and Three Phenolic Glycosides in Lamium takesimense Nakai

Nugroho A, Park KS, Seo DJ, Park HJ

The herbs of Lamium takesimense Nakai (Lamiaceae) is used to treat spasmodic and inflammatory disease. The four polar compounds, ecdysterone, isoacteoside, rutin and lamiuside C, were isolated and identified from...
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The Clinical Couse and Echocardiographic Findings of Long-Term Angiotensin Converting Enzyme Inhibitor Therapy in the Patients with Severe Chronic Congestive Heart Failure

Son JW, Bae SM, Kam DH, Kim KD, Dho HK, Kim MH, Kim JS

BACKGROUND: Congestive heart failure is a serious and growing clinical problem. Diuretics and digitalis glycosides remain the traditional regimens of therapy in patients with congestive heart failure, however, angiotensin coverting...
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Lack of Mutagenicity Potential of Periploca sepium Bge. in Bacterial Reverse Mutation (Ames) Test, Chromosomal Aberration and Micronucleus Test in Mice

Zhang MS, Bang IS, Park CB

  • KMID: 2380181
  • Environ Health Toxicol.
  • 2012 ;27(1):e2012014.
OBJECTIVES: The root barks of Periploca sepium Bge. (P. sepium) has been used in traditional Chinese medicine for healing wounds and treating rheumatoid arthritis. However, toxicity in high-doses was often...
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Effects of Triterpenoid Glycosides from Fresh Ginseng Berry on SW480 Human Colorectal Cancer Cell Line

Xie JT, Du GJ, McEntee E, Aung HH, He H, Mehendale , Wang CZ, Yuan CS

  • KMID: 1804675
  • Cancer Res Treat.
  • 2011 Mar;43(1):49-55.
PURPOSE: The pharmacological activities, notably the anticancer properties, of bioactive constituents fromfresh American ginseng berry have not yet been well studied. In this study, we investigated the antiproliferative effects of...
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Phenolic Constituents from the Flowers of Hamamelis japonica Sieb. et Zucc.

Yim SH, Lee YJ, Park KD, Lee IS, Shin BA, Jung DW, Williams D, Kim HJ

Hamamelis japonica (Hamamelidaceae), widely known as Japanese witch hazel, is a deciduous flowering shrub that produces compact clumps of yellow or orange-red flowers with long and thin petals. As a...
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Determination of Cyanogenic Compounds in Edible Plants by Ion Chromatography

Cho HJ, Do BK, Shim SM, Kwon H, Lee DH, Nah AH, Choi YJ, Lee SY

  • KMID: 2317828
  • Toxicol Res.
  • 2013 Jun;29(2):143-147.
Cyanogenic glycosides are HCN-producing phytotoxins; HCN is a powerful and a rapidly acting poison. It is not difficult to find plants containing these compounds in the food supply and/or in...
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Digitalis-like Toxic Symptoms Occurring after Accidental Nerium indicum Poisoning

Song YW, Ahn JH, Lee CA, Kim GW, Choi SC, Jung YS

  • KMID: 2101618
  • J Korean Soc Clin Toxicol.
  • 2009 Jun;7(1):19-22.
Although Nerium indicum poisoning is a globally rare occurrence, Nerium oleander poisoning is known to occur frequently in the Mediterranean regions. To our knowledge, this is the first reported case...
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Anti-inflammatory Triterpenes and Glyceryl Glycosides from Kandelia candel (L.) Druce

Dat LD, Thao NP, Tai BH, Luyen BT, Yang SY, Kim S, Koo JE, Koh YS, Cuong NT, Nam NH, Thanh NV, Kiem PV, Minh CV, Kim YH

Phytochemical investigation of Kandelia candel resulted in the isolation of six triterpenes (1 - 5) and two glyceryl glycosides (6 and 7) and their structures were determined by comparing the...
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The Change of Ginsenoside Composition in the Ginseng (Panax ginseng) Flower Buds by the Ultrasonication and Vinegar Process

Gwak HH, Hong JT, Ahn CH, Kim KJ, Kim SG, Yoon SS, Im BO, Cho SH, Nam YM, Ko SK

The purpose of this study was to develop a new ginseng (Panax ginseng) flower buds extract with the high concentration of ginsenoside Rg3, Rg5, Rk1, Rh1 and F4, the Red...
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Quantitative Measurement of Membrane Na+-K+ ATPase Activity using Thallium-201: Comparison with Rubidium-86

Lee JT, Lee IK, Sohn SK, Lee KB

  • KMID: 2078673
  • Korean J Nucl Med.
  • 1998 Apr;32(2):121-128.
PURPOSE: Na+-K+ ATPase Activity has beem estimated by the degree of inhibition of cation transport by cardiac glycosides (ouabain) using Rb-86 as a substrate. The biological characterist-Isc of T1-201 is...
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Pharmacological Activities and Applications of Spicatoside A

Ramalingam M, Kim SJ

Liriopogons (Liriope and Opiopogon) species are used as a main medicinal ingredient in several Asian countries. The Liriopes Radix (tuber, root of Liriope platyphylla) has to be a promising candidate...
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Delphinidin inhibits cell proliferation and induces apoptosis in MDA-MB-231 human breast cancer cell lines

Seo EY

  • KMID: 2327130
  • J Nutr Health.
  • 2013 Dec;46(6):503-510.
Breast cancer is the most common malignancy in women, both in the developed and developing countries. Anthocyanins are natural coloring of a multitude of foods, such as berries, grapes or...
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Analysis of Essential oil, Quantification of Six Glycosides, and Nitric Oxide Synthase Inhibition Activity in Caryopteris incana

Nugroho A, Lee SK, Kim D, Choi JS, Park KS, Song BM, Park HJ

Caryopteris incana (Verbenaceae) has been used to treat cough, arthritis, and eczema in Oriental medicine. The two fractions (CHCl₃- and BuOH fractions) and the essential oil of the plant material...
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