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Interferon-gamma (IFN-gamma) increases CD1 expression through inhibition of IL-10 secretion from M.leprae-infected macrophages of lepromatous leprosy

Lee SB, Kim SK, Lee HJ, Shin HK, Kim JP, Ko YH, Kim SH, Chae GT

  • KMID: 1584949
  • Korean Lepr Bull.
  • 2000 Dec;33(2):47-54.
The CD1 system is a novel antigen-presenting system for T cell recognition of lipid and glycolipids in antimicrobial immunity. Lepromatous leprosy is characterized by lack of cell-mediated immunity against M.leprae....
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Pathogenesis of Anti-MAG Antibody Associated with Demyelinating Peripheral Neuropathy: Expression of Anti-MAG Antibody in Ebstein-Barr Virus Transformed Lymphocytes of Umbrical Cord

Lee KW, Kim JS, Lee SH, Lee KH, Ju IS

  • KMID: 2065972
  • J Korean Neurol Assoc.
  • 1995 Mar;13(1):39-46.
It is not unconimm that the monoclonal gammopathies occur in patients with demyelinating peripheral neuropathy. The IgM.-protein from those patients reacted with peripheral nerve myelin, which was first identified as...
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Co-expression of CdtA and CdtC subunits of cytolethal distending toxin from Aggregatibacter actinomycetemcomitans

Lee SJ, Lee KY, Kim HS

  • KMID: 2321649
  • J Korean Acad Periodontol.
  • 2009 Aug;39(Suppl):231-237.
PURPOSE: Cytolethal distending toxin (CDT) is a family of heat-labile cytotoxins produced by several gram-negative mucosa-associated pathogens, including Aggregatibacter actinomycetemcomitans. CDT is well known to be capable of inducing growth...
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Solitary Duodenal Metastasis from Breast Cancer

Park KH, Bae JS, Chae BD, Hong KM, Lee CW, Lee SI

  • KMID: 2324766
  • J Korean Surg Soc.
  • 2008 Jan;74(1):76-78.
A 65-year-old female patient experienced melena for 10 days. Gastroduodenoscopy revealed a tumor in the duodenum, a portion of which was taken for biopsy, which showed a malignant tumor. She...
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Mannosylerythritol lipids ameliorate ultraviolet A-induced aquaporin-3 downregulation by suppressing c-Jun N-terminal kinase phosphorylation in cultured human keratinocytes

Bae IH, Lee SH, Oh S, Choi H, Marinho PA, Yoo JW, Ko JY, Lee ES, Lee TR, Lee CS, Kim DY

Mannosylerythritol lipids (MELs) are glycolipids and have several pharmacological efficacies. MELs also show skin-moisturizing efficacy through a yet-unknown underlying mechanism. Aquaporin-3 (AQP3) is a membrane protein that contributes to the...
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Analysis of Lyso-Globotriaosylsphingosine in Dried Blood Spots

Johnson B, Mascher H, Mascher D, Legnini E, Hung CY, Dajnoki A, Chien YH, Marodi L, Hwu WL, Bodamer OA

Recently, lyso-globotriaosylsphingosine (lyso-Gb3) was found to be elevated in plasma of treatment naive male patients and some female patients with Fabry Disease (FD). This study tested whether lyso-Gb3 could be...
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Comparison of DNA fragment patterns between the phenolic glycolipid-Tb producers and non-producers of Mycobacterium tuberculosis

Lee TY, Cho SN, Yoon KH, Shin JS, Kim JD

Differences in ability to produce the specific phenolic glycolipid-Tb (PGL-Tb) antigen among Mycobacterium tuberculosis strains have been reported. One of the explanations would be the genotypic variation between the strains....
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Detection of Phenolic Glycolipid I of Mycobacterium leprae and Antibodies to the Antigen in Sera from Leprosy Patients and Their Contacts

Cho SN, Shin JS, Choi IH, Kim SH, Kim DI, Kim JD

Serum specimens from leprosy patients, their contacts and controls were examined for the presence of phenolic glycolipid I (PGL-I), a Mycobacterium leprae specific antigen, and antibodies to the antigen...
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Interleukin-1 beta production by monocytes from leprosy patients

Choi IH, Shin JS, Park SK, Cho SN, Kim JD, Kim SJ

The cause responsible for the lack of an efficient cell-mediated immunity or a delayed type hypersensitivity to M. leprae in lepromatous patients is poorly understood. But the resistance to M....
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