- Estrogen receptor 1, Glutathione S-transferase P1, Glutathione S-transferase M1, and Glutathione S-transferase T1 Genes with Dysmenorrhea in Korean Female Adolescents
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Woo HY, Kim KH, Lim SW
- KMID: 1096823
- Korean J Lab Med.
- 2010 Feb;30(1):76-83.
- doi: 10.3343/kjlm.2010.30.1.76
BACKGROUND: Dysmenorrhea is the most common gynecologic complaint among adolescent females. We investigated the association between genetic polymorphisms and dysmenorrhea. METHODS: A total of 202 postmenarcheal Korean female adolescents 16-17... -
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- GSTM1, GSTT1 and GSTP1 Polymorphisms in the Korean Population
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Cho HJ, Lee SY, Ki CS, Kim JW
- KMID: 2157771
- J Korean Med Sci.
- 2005 Dec;20(6):1089-1092.
- doi: 10.3346/jkms.2005.20.6.1089
The isoenzymes of the glutathione s transferase (GST) family play a vital role in phase II of biotransformation of many substances. Using a multiplex polymerase chain reaction and a direct... -
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- Immunohistochemical Study on the Expression of Topoisomerase II alpha and Glutathione S-Transferase pi in Acute Myeloid Leukemia
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Kim BK, Jeong YS, Chang CH, Son HC, Kim SH, Sol MY, Lee EY
- KMID: 2089488
- Korean J Clin Pathol.
- 1998 Jun;18(2):107-114.
BACKGROUND: Topoisomerase II (topo II) is a major target of anthracyclines and epipodophyllotoxins for anticancer treatment. The expression of topo II is low in drug resistant cell lines. High levels... -
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- Association between Glutathione S-Transferase T1, M1, and P1 Genotypes and the Risk of Colorectal Cancer
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Cong N, Liu L, Xie Y, Shao W, Song J
- KMID: 2069929
- J Korean Med Sci.
- 2014 Nov;29(11):1488-1492.
- doi: 10.3346/jkms.2014.29.11.1488
Glutathione S-transferases (GSTs) are enzymes which play an important role in the neutralization of toxic compounds and eradication of electrophilic carcinogens. Genetic polymorphisms within the genes encoding for GSTs may... -
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- Clinical Usefulness of Flow Cytometric Measurement of P-glycoprotein, Glutathione S-Transferase pie and Topoisomerase II alpha Expression in Adult Acute Myelogenous Leukemia
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Lee JN, Lee EY, Cho GJ
- KMID: 2143365
- Korean J Hematol.
- 1999 Aug;34(3):416-427.
BACKGROUND: P-glycoprotein (PGP) is capable of expelling cytotoxic drugs from cytosol and the overexpression mediates drug resistance. However not all resistant leukemic cells express PGP. High expression of glutathione S-transferasepie... -
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- Lack of Association of Glutathione S-transferase P1 Ile105Val Polymorphism with Aspirin-Intolerant Asthma
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Oh JM, Kim SH, Suh CH, Nahm DH, Park HS, Lee YM, Lee JH, Park CS, Shin HD
- KMID: 1782235
- Korean J Intern Med.
- 2005 Sep;20(3):232-236.
- doi: 10.3904/kjim.2005.20.3.232
BACKGROUND: Glutathion S-transferase P1 (GSTP1), the abundant isoform of glutathione S-transferase in lung epithelium, plays an important role in cellular protection against oxidative stress and toxic foreign chemicals. GSTP1 (Ile105Val)... -
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- Change in the Gene Expression of HOS Cell Line by 17beta-Estradiol -Study using cDNA Array-
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Yoo CI, Suh JT, Kim JI, Kim CM
- KMID: 2199153
- J Korean Orthop Res Soc.
- 2000 Apr;3(1):78-95.
Osteoporosis is caused by the decrease in bone mass associated with disturbance in bone remodeling. Bone remodeling depends on the spatial and temporal coupling of bone formation by osteoblasts and... -
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- GSTM1 and GSTP1 Polymorphisms as Potential Factors for Modifying the Effect of Smoking on Inflammatory Response
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Kim JH, Park SG, Lee KH, Choi JH, Ha EH, Myung SK, Hong YC
- KMID: 1713112
- J Korean Med Sci.
- 2006 Dec;21(6):1021-1027.
- doi: 10.3346/jkms.2006.21.6.1021
Inflammation has been known to be an important underlying condition for development of various diseases including cancer. The aims of this study were to investigate whether tobacco smoke exposure increases... -
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- Treatment Outcome of Multidrug Resistance Related mRNA Expression and c-Jun-N-Terminal Kinase Activity in Patients with Acute Myeloid Leukemia
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Do JH, Oh SH, Song EJ, Chung JS, Kang CD, Lee EY
- KMID: 1781489
- Korean J Lab Med.
- 2007 Aug;27(4):229-236.
- doi: 10.3343/kjlm.2007.27.4.229
BACKGROUND: The multidrug resistance (mdr1), multidrug resistance associated protein (mrp1), and glutathione-s-transferase (gst) pi genes have been associated with treatment failure in acute myeloid leukemia (AML). c-jun N-terminal kinase... -
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- Association of the GSTP1 and NQO1 Polymorphisms and Head and Neck Squamous Cell Carcinoma Risk
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Cho CG, Lee SK, Nam SY, Lee MS, Lee SW, Choi EK, Park HJ, Kim SY
- KMID: 1713122
- J Korean Med Sci.
- 2006 Dec;21(6):1075-1079.
- doi: 10.3346/jkms.2006.21.6.1075
The GSTP1 and NQO1 have been reported to be associated with an increased risk for smoking related head and neck squamous cell carcinoma (HNSCC). The purpose of this study was... -
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