- Expression of Alpha Smooth Muscle Actin and Lysozyme in Various Glomerular Diseases
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Sung SH, Han WS
- KMID: 1725344
- Korean J Pathol.
- 1998 Jan;32(1):51-57.
The cells of glomerular mesangium is composed mostly of intrinsic contractile mesangial cells and a few macrophages. Injury to the mesangium is central to many glomerular diseases. This study was... -
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- A Case of IgA Nephropathy Associated with Leptospirosis
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Shin HS, Lee SE, Lee SW, Chung BH, Hwang TJ, Kwak JH
- KMID: 2307222
- Korean J Nephrol.
- 2007 Sep;26(5):630-633.
Leptospirosis is a spirochaetal infectious disease caused by Leptospira interrogans. Multiple organ involvement may be encountered in leptospirosis. Early renal involvement is very common and characterized by tubulo-interstitial nephritis and... -
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- Circulating factors in sera or peripheral blood mononuclear cells in patients with membranous nephropathy or diabetic nephropathy
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Ihm CG, Park JK, Hong SP, Lee TW, Cho BS, Kim MJ
- KMID: 645115
- J Korean Med Sci.
- 1997 Dec;12(6):539-544.
- doi: 10.3346/jkms.1997.12.6.539
In order to investigate the status of some circulating factors in nephrotic syndrome, we examined the secretion of monocyte chemotactic peptide (MCP)-1, tumor necrosis factor (TNF) alpha or fibronectin... -
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- A Study of Glomerullar Minimal Lesion and Minimal Mesangial Proliferation with or without Nephrotic Syndrome; Pathologic, Immunopathologic and Clinical Correlations
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Choi IJ, Jeong HJ, Kim PK, Lee JS, Kim KS, Lee HY, Chung SH, Kim DS
- KMID: 693010
- Yonsei Med J.
- 1986 Mar;27(1):17-24.
- doi: 10.3349/ymj.1986.27.1.17
A total of 394 cases of minimal lesion were reviewed and reassessed clinically and by laboratory investiga- tion, for 4 years from 1979 to 1982. Association with nephrotic syndrome is... -
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- Electron microscopic study of the cases of minimal change nephrotic syndrome with mesangial IgA deposition
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Jeong HJ, Jung SH, Choi IJ
- KMID: 2036543
- Yonsei Med J.
- 1992 Dec;33(4):351-356.
- doi: 10.3349/ymj.1992.33.4.351
Twenty-five cases of minimal change nephrotic syndrome(minimal change disease, MCD) with mesangial IgA deposition were evaluated electron microscopically. The thickness of the glomerular basement membrane(GBM) was 3875 +/- 1271 A... -
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- Role of mononuclear cells of IgA nephropathy on ICAM-1 expression in mesangial cells
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Lee TW, Park JK, Ahn JH, Ihm CG, Kim MJ
- KMID: 759058
- Korean J Intern Med.
- 1998 Feb;13(1):27-32.
OBJECTIVES: To investigate the possible role of mononuclear cells and their products in the pathogenesis of IgA nephropathy, in vitro expression of ICAM-1 on cultured mouse mesangial cell (MC) was... -
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- Expression of Osteopontin and Transforming Growth Factor-beta in Childhood Minimal Change Nephrotic Syndrome After Cyclosporine Treatment
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Lim BJ, Kim PK, Hong SW, Jeong HJ
- KMID: 2322066
- J Korean Soc Pediatr Nephrol.
- 2002 Oct;6(2):142-154.
PURPOSE: One of the most important adverse effects of long-term cyclosporine therapy is nephrotoxicity, the morphologic changes of which include interstitial fibrosis and arteriolar hyalinization. Recently, several authors have shown... -
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- The Inhibitory Effect of siRNAs on The High Glucose-Induced Overexpression of TGF-beta1 in Mesangial Cells
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Noh HJ, Kim HC, Lee SS, Kang YN, Chae YM, Park KK
- KMID: 1778423
- J Korean Med Sci.
- 2006 Jun;21(3):430-435.
- doi: 10.3346/jkms.2006.21.3.430
Diabetic nephropathy is characterized by an expansion of the glomerular mesangium, caused by mesangial cell proliferation and an excessive accumulation of extracellar matrix (ECM) proteins, which eventually leading to glomerulosclerosis.... -
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- Immunoglobulin A nephropathy in patients with non-insulin dependent diabetes mellitus
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Lee EY, Chung CH, Choi SO
- KMID: 646030
- J Korean Med Sci.
- 1999 Oct;14(5):582-585.
- doi: 10.3346/jkms.1999.14.5.582
The occurrence of immunoglobulin A nephropathy (IgAN) in patients with noninsulin dependent diabetes mellitus (NIDDM) is a rare event and of pathogenetic interest. It is not clear whether this is... -
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- Mononuclear Cells Stimulate Leukocyte Adhesion Molecule Expression and Fibronectin Secretion in Mesangial Cells
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Ihm CG, Park JK, Hong SP, Lee TW, Kim MJ, Cho BS
- KMID: 2254962
- Korean J Nephrol.
- 1998 May;17(3):376-382.
BACKGROUNDS: The mesangial extracellular matrix expansion appear to be important features of progressive glomerular diseases and the mononuclear cells may play a pivotal role in this process. METHOD: We evaluated... -
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- Modification of Hyperacute Xenograft Rejection of a Porcine Kidney by Serial Organ Perfusion of Canine Blood Through the Pig's Liver and Kidney
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Oh CK, Jeong HJ, Kim JH, Wang HJ, Kim MW
- KMID: 2095545
- J Korean Surg Soc.
- 1999 Jan;56(1):1-19.
BACKGROUND: The major problem in transplants between widely disparate species is hyperacute rejection, a rapid and violent rejection that damages the graft within minutes or hours. Hyperacute rejection is mediated... -
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- Effect of IgA Aggregates on Transforming Growth Factor-beta1 Production in Human Mesangial Cells and the Intraglomerular Expression of Transforming Growth Factor-beta1 in Patients with IgA Nephropathy
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Han SY, Ihm CG, Cha DR, Kang YS, Han KH, Kim HK, Han JY
- KMID: 1776695
- Korean J Intern Med.
- 2005 Mar;20(1):40-47.
- doi: 10.3904/kjim.2005.20.1.40
BACKGROUND: Transforming growth factor-beta (TGF-beta) stimulates renal fibrosis in various renal diseases including IgA nephropathy. METHODS: We examined whether immunoglobulin A (IgA) stimulated TGF-beta1 synthesis in human mesangial cells (MCs),... -
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- Significance of mesangial IgA deposition in minimal change nephrotic syndrome: a study of 60 cases
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Choi IJ, Jeong HJ, Lee HY, Kim PK, Lee JS, Han DS
- KMID: 1107344
- Yonsei Med J.
- 1990 Sep;31(3):258-263.
- doi: 10.3349/ymj.1990.31.3.258
We studied 60 cases of minimal change nephrotic syndrome (MCNS) with mesangial IgA deposits occurring over a 6 year period. There were 43 adults and 17 children. Hematuria occurred in... -
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- The effect of lovastatin on proliferation of cultured rat mesangial and aortic smooth muscle cells
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Choi KH, Kang SW, Lee SW, Lee HY, Han DS, Kang BS
- KMID: 1123180
- Yonsei Med J.
- 1995 Jun;36(3):251-261.
- doi: 10.3349/ymj.1995.36.3.251
In order to investigate the anti-proliferative effect of 3-hydroxy-3-methylglutaryl coenzyme. A reductase inhibitor, we evaluated the effects of lovastatin on DNA replication and the proliferation of rat mesangial and aortic... -
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- Rapamycin Inhibits Platelet-Derived Growth Factor- Induced Collagen, but Not Fibronectin, Synthesis in Rat Mesangial Cells
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Kim MS, Park J, Ha H, Kim YS, Kang SW, Jeong HJ, Kang DH, Yang CW
- KMID: 1726177
- Yonsei Med J.
- 2004 Dec;45(6):1121-1126.
- doi: 10.3349/ymj.2004.45.6.1121
Rapamycin, a macrocyclic lactone, is effective in reducing the incidence of acute rejection after renal transplantation. The inhibitory effects of rapamycin on lymphocyte proliferation and the molecular mechanisms that were... -
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- Two Cases of Isolated Diffuse Mesangial Sclerosis with WT1 Mutations
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Hahn H, Cho YM, Park YS, You HW, Cheong HI
- KMID: 2157801
- J Korean Med Sci.
- 2006 Feb;21(1):160-164.
- doi: 10.3346/jkms.2006.21.1.160
Here we report two cases of isolated diffuse mesangial sclerosis (IDMS) with early onset end-stage renal failure. These female patients did not show abnormalities of the gonads or external genitalia.... -
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- Chemokines, osteopontin, ICAM-1 gene expression in cultured rat mesangial cells
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Lee SK, Park JY, Chung SJ, Yang WS, Kim SB, Park SK, Park JS
- KMID: 1064964
- J Korean Med Sci.
- 1998 Apr;13(2):165-170.
- doi: 10.3346/jkms.1998.13.2.165
To investigate whether MCP-1, CINC, RANTES, osteopontin and ICAM-1 mRNA could be induced in cultured rat mesangial cells by interleukin-1beta(IL-1beta), tumor necrosis factor-alpha (TNF-alpha) and lipopolysaccharide (LPS), and whether ... -
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- Effects of High Glucose on Interleukin-6 Production in Human Mesangial Cells
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Ihm CG, Park JK, Kim HJ, Lee TW, Cha DR
- KMID: 648677
- J Korean Med Sci.
- 2002 Apr;17(2):208-212.
- doi: 10.3346/jkms.2002.17.2.208
Interleukin (IL)-6 is an autocrine growth factor for mesangial cells. It is not known whether high glucose influences IL-6 production in mesangial cells. Angiotensin II (AGII) is involved in the... -
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- Effects of mixed leukocyte reaction, hydrocortisone and cyclosporine on expression of leukocyte adhesion molecules by endothelial and mesangial cells
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Ihm CG, Hong SP, Park JK, Lee TW, Cho BS, Yang MH, Kim MJ
- KMID: 645013
- J Korean Med Sci.
- 1996 Dec;11(6):495-500.
- doi: 10.3346/jkms.1996.11.6.495
We investigated the effects of mixed leukocyte reaction (MLR), hydrocortisone (HC) and cyclosporine A (CsA) on the expression of leukocyte adhesion molecules on the mesangial (MC) and endothelial cells (EnC).... -
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- The Protective Effects of Green Tea Extract against L-arginine Toxicity to Cultured Human Mesangial Cells
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Shin BC, Ryu HH, Chung JH, Lee BR, Kim HL
- KMID: 1778163
- J Korean Med Sci.
- 2009 Jan;24(Suppl 1):S204-S209.
- doi: 10.3346/jkms.2009.24.S1.S204
The aim of this study was to investigate whether green tea extract (GTE) has the protective effects on excess L-arginine induced toxicity in human mesangial cell. Human mesangial cells treated... -
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