J Korean Med Sci.  1999 Oct;14(5):582-585. 10.3346/jkms.1999.14.5.582.

Immunoglobulin A nephropathy in patients with non-insulin dependent diabetes mellitus

• Lee EY
• Chung CH
• Choi SO

• KMID: 646030
• DOI: http://doi.org/10.3346/jkms.1999.14.5.582

Abstract

The occurrence of immunoglobulin A nephropathy (IgAN) in patients with noninsulin dependent diabetes mellitus (NIDDM) is a rare event and of pathogenetic interest. It is not clear whether this is merely coincidence. We report here five patients with IgAN in NIDDM associated with or without diabetic glomerulosclerosis. All of the patients were Korean males. In three patients, diabetes mellitus was diagnosed at the same time with diagnosis of IgAN, and the known duration of the diabetes in the other two patients were three and seven years, respectively. There was no evidence of diabetic retinopathy in four patients, but it was found in one patient. In all cases, the diagnosis of IgAN was made by immunohistology.

Keyword

Glomerulonephritis, IgA; Diabetes mellitus, non-insulin-dependent

MeSH Terms

Adult
Biopsy
Case Report
Complement 3/analysis
Diabetes Mellitus, Non-Insulin-Dependent/complications*
Diabetic Nephropathies/pathology*
Glomerular Mesangium/pathology
Glomerulonephritis, IGA/pathology*
Glomerulonephritis, IGA/etiology
Human
IgG/analysis
Kidney Glomerulus/pathology
Male
Microscopy, Fluorescence
Middle Age