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Complete Sequence of the Mitochondrial Genome of Spirometra ranarum: Comparison with S. erinaceieuropaei and S. decipiens

Jeon HK, Park H, Lee D, Choe S, Kang Y, Bia MM, Lee SH, Eom KS

This study was undertaken to determine the complete mitochondrial DNA sequence and structure of the mitochondrial genome of Spirometra ranarum, and to compare it with those of S. erinaceieuropaei and...
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Spectrum of mitochondrial genome instability and implication of mitochondrial haplogroups in Korean patients with acute myeloid leukemia

Kim HR, Kang MG, Lee YE, Na BR, Noh MS, Yang SH, Shin JH, Shin MG

BACKGROUND: Mitochondrial DNA (mtDNA) mutations may regulate the progression and chemosensitivity of leukemia. Few studies regarding mitochondrial aberrations and haplogroups in acute myeloid leukemia (AML) and their clinical impacts have...
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Differential Diagnosis of Human Sparganosis Using Multiplex PCR

Jeon HK, Kim KH, Sohn WM, Eom KS

Human sparganosis was diagnosed by morphological and genetic analyses in Korea. The complete mitochondrial genomes of Spirometra erinaceieuropaei and S. decipiens isolated in Korea have been recorded. Present study was...
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Complete Mitochondrial Genome of the Chagas Disease Vector, Triatoma rubrofasciata

Dong L, Ma X, Wang M, Zhu D, Feng Y, Zhang Y, Wang J

Triatoma rubrofasciata is a wide-spread vector of Chagas disease in Americas. In this study, we completed the mitochondrial genome sequencing of T. rubrofasciata. The total length of T. rubrofasciata mitochondrial...
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Congenital Orbital Fibrosis: Molecular Genetic Analysis by Whole-Exome and Mitochondrial Genome Sequencing

Ko J, Lee HJ, Lee JS, Yoon JS

A 3-year-old girl presented with congenital orbital fibrosis. We performed molecular genetic analysis by whole exome and mitochondrial genome sequencing. No pathologic mutation was identified in the present case. To...
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Analysis of Nuclear Mitochondrial DNA Segments of Nine Plant Species: Size, Distribution, and Insertion Loci

Ko YJ, Kim S

Nuclear mitochondrial DNA segment (Numt) insertion describes a well-known phenomenon of mitochondrial DNA transfer into a eukaryotic nuclear genome. However, it has not been well understood, especially in plants. Numt...
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Complete Mitochondrial Genome of Anoplocephala magna Solidifying the Species

Guo A

The 2 species of the genus Anoplocephala (Anoplocephalidae), A. perfoliata and A. magna, are among the most important equine cestode parasites. However, there is little information about their differences at...
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Complete Mitochondrial Genome of Echinostoma hortense (Digenea: Echinostomatidae)

Liu ZX, Zhang Y, Liu YT, Chang QC, Su X, Fu X, Yue DM, Gao Y, Wang CR

Echinostoma hortense (Digenea: Echinostomatidae) is one of the intestinal flukes with medical importance in humans. However, the mitochondrial (mt) genome of this fluke has not been known yet. The present...
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Clinicopathological Implications of Mitochondrial Genome Alterations in Pediatric Acute Myeloid Leukemia

Kang MG, Kim YN, Lee JH, Szardenings M, Baek HJ, Kook H, Kim HR, Shin MG

BACKGROUND: To the best of our knowledge, the association between pediatric AML and mitochondrial aberrations has not been studied. We investigated various mitochondrial aberrations in pediatric AML and evaluated their...
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Complete Mitochondrial Genome of a Tongue Worm Armillifer agkistrodontis

Li J, He FN, Zheng HX, Zhang RX, Ren YJ, Hu W

Armillifer agkistrodontis (Ichthyostraca: Pantastomida) is a parasitic pathogen, only reported in China, which can cause a zoonotic disease, pentastomiasis. A complete mitochondrial (mt) genome was 16,521 bp comprising 13 protein-coding...
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Sequence Analysis of Mitochondrial Genome of Toxascaris leonina from a South China Tiger

Li K, Yang F, Abdullahi , Song M, Shi X, Wang M, Fu Y, Pan W, Shan F, Chen W, Li G

Toxascaris leonina is a common parasitic nematode of wild mammals and has significant impacts on the protection of rare wild animals. To analyze population genetic characteristics of T. leonina from...
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Mitochondrial Genome Sequences of Spirometra erinaceieuropaei and S. decipiens (Cestoidea: Diphyllobothriidae)

Eom KS, Park H, Lee D, Choe S, Kim KH, Jeon HK

The present study was performed to compare the mitochondrial genomes between 2 Spirometra tapeworms, Spirometra erinaceieuropaei and Spirometra decipiens (Cestoidea: Diphyllobothriidae), which larval stages are important etiological agents of sparganosis...
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A developmental perspective on the origins of obesity and metabolic syndrome

Choi YS, Hwang IT

Metabolic syndrome comprises central obesity, dyslipidemia, hypertension, glucose intolerance, and insulin resistance. Children sometimes develop metabolic syndrome, and it is strongly associated with the same syndrome in adulthood. Recently, there...
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Whole Mitochondrial Genome Sequence of an Indian Plasmodium falciparum Field Isolate

Tyagi S, Pande V, Das A

Mitochondrial genome sequence of malaria parasites has served as a potential marker for inferring evolutionary history of the Plasmodium genus. In Plasmodium falciparum, the mitochondrial genome sequences from around the...
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Genetics of Mitochondrial Myopathies

Shin JH, Kim DS

Mitochondrion is an intracellular organelle with its own genome. Its function in cellular metabolism is indispensable that mitochondrial dysfunction gives rise to multisystemic failure. The manifestation is most prominent with...
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Complete Mitochondrial Genome of Haplorchis taichui and Comparative Analysis with Other Trematodes

Lee D, Choe S, Park H, Jeon HK, Chai JY, Sohn WM, Yong TS, Min DY, Rim HJ, Eom KS

Mitochondrial genomes have been extensively studied for phylogenetic purposes and to investigate intra- and interspecific genetic variations. In recent years, numerous groups have undertaken sequencing of platyhelminth mitochondrial genomes. Haplorchis...
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Mechanisms of Uniparental Mitochondrial DNA Inheritance in Cryptococcus neoformans

Gyawali R, Lin X

  • KMID: 2312648
  • Mycobiology.
  • 2011 Dec;39(4):235-242.
In contrast to the nuclear genome, the mitochondrial genome does not follow Mendelian laws of inheritance. The nuclear genome of meiotic progeny comes from the recombination of both parental genomes,...
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Re-engineering the mitochondrial genomes in mammalian cells

Yoon YG, Koob MD, Yoo YH

Mitochondria are subcellular organelles composed of two discrete membranes in the cytoplasm of eukaryotic cells. They have long been recognized as the generators of energy for the cell and also...
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Back to the Ends: Chromosomal DNA

Lee MH, Suh D

  • KMID: 2322080
  • J Korean Soc Pediatr Nephrol.
  • 2008 Apr;12(1):1-10.
Nucleic scids transfer the genetic information for serving a central biological purpose. The nucleic acids are polymers of nucleotides and they are mainly ribonucleic acid(RNA) and deoxyribonucleic acid(DNA). The nucleotides...
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Screening of the A11084G Polymorphism and Scanning of a Mitochondrial Genome SNP in Korean Migraineurs

Kang L, Lee ST, Im W, Kim SC, Hun KS, Kim BK, Kim M

BACKGROUND AND PURPOSE: Migraine is a genetically heterogeneous disorder that is frequently associated with a familial history, and mitochondrial dysfunction has been suggested to be associated with its pathogenesis. We...
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