Korean J Parasitol.  2016 Dec;54(6):803-807. 10.3347/kjp.2016.54.6.803.

Sequence Analysis of Mitochondrial Genome of Toxascaris leonina from a South China Tiger

• Li K
• Yang F
• Abdullahi
• Song M
• Shi X
• Wang M
• Fu Y
• Pan W
• Shan F
• Chen W
• Li G

• KMID: 2367423
• DOI: http://doi.org/10.3347/kjp.2016.54.6.803

Abstract

Toxascaris leonina is a common parasitic nematode of wild mammals and has significant impacts on the protection of rare wild animals. To analyze population genetic characteristics of T. leonina from South China tiger, its mitochondrial (mt) genome was sequenced. Its complete circular mt genome was 14,277 bp in length, including 12 protein-coding genes, 22 tRNA genes, 2 rRNA genes, and 2 non-coding regions. The nucleotide composition was biased toward A and T. The most common start codon and stop codon were TTG and TAG, and 4 genes ended with an incomplete stop codon. There were 13 intergenic regions ranging 1 to 10 bp in size. Phylogenetically, T. leonina from a South China tiger was close to canine T. leonina. This study reports for the first time a complete mt genome sequence of T. leonina from the South China tiger, and provides a scientific basis for studying the genetic diversity of nematodes between different hosts.

Keyword

Toxascaris leonina; mitochondrial genome; phylogeny; South China tiger

MeSH Terms

Animals
Animals, Wild
Bias (Epidemiology)
China*
Codon, Initiator
Codon, Terminator
DNA, Intergenic
Genes, rRNA
Genetic Variation
Genome
Genome, Mitochondrial*
Mammals
Phylogeny
RNA, Transfer
Sequence Analysis*
Tigers*
Toxascaris*
Codon, Initiator
Codon, Terminator
DNA, Intergenic
RNA, Transfer