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Imidacloprid inhibits IgE-mediated RBL-2H3 cell degranulation and passive cutaneous anaphylaxis

Shi L, Zou L, Gao J, Xu H, Shi X, Chen H

BACKGROUND: Imidacloprid has been commonly used as a pesticide for crop protection and acts as nicotinic acetylcholine receptor agonists. Little information about the relationship between imidacloprid and allergy is available. OBJECTIVE:...
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Influencing Factors of High PTSD Among Medical Staff During COVID-19: Evidences From Both Meta-analysis and Subgroup Analysis

Qi G, Yuan P, Qi M, Hu X, Shi S, Shi X

Background PTSD (Post-traumatic stress disorder, PTSD) had a great impact on health care workers during the COVID-19 (Corona Virus Disease 2019, COVID-19). Better knowledge of the prevalence of PTSD and its...
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Genetic heterogeneity of Pneumocystis carinii from rats of several regions and strains

Chung BS, Pars YK, Huh S, Yu JR, Kim J, Shi X, Cho SR, Lee SH, Hong ST

Pneumocystis carinii is a major opportunistic pathogen which has been found in the lungs of a wide variety of mammalian host species, and the fact suggests the possibility of intraspecific...
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Next-generation sequencing for the genetic characterization of Maedi/Visna virus isolated from the northwest of China

Zhao L, Zhang L, Shi X, Duan X, Li H, Liu S

Background: Maedi/Visna virus (MVV) is a contagious viral pathogen that causes considerable economic losses to the sheep industry worldwide. Objectives: In China, MVV has been detected in several regions, but its...
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Sequence Analysis of Mitochondrial Genome of Toxascaris leonina from a South China Tiger

Li K, Yang F, Abdullahi , Song M, Shi X, Wang M, Fu Y, Pan W, Shan F, Chen W, Li G

Toxascaris leonina is a common parasitic nematode of wild mammals and has significant impacts on the protection of rare wild animals. To analyze population genetic characteristics of T. leonina from...
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TCN1 Deficiency Inhibits the Malignancy of Colorectal Cancer Cells by Regulating the ITGB4 Pathway

Zhu X, Jiang X, Zhang Q, Huang H, Shi X, Hou D, Xing C

Background/Aims: This study aimed to investigate the biological function and regulatory mechanism of TCN1 in colorectal cancer (CRC). Methods: We studied the biological function of TCN1 by performing gain-of-function and loss-offunction...
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CD31 and D2-40 Contribute to Peritoneal Metastasis of Colorectal Cancer by Promoting Epithelial-Mesenchymal Transition

Zhu X, Zhou G, Ni P, Jiang X, Huang H, Wu J, Shi X, Jiang X, Liu J

Background/Aims: Colorectal cancer (CRC) patients often exhibit peritoneal metastasis, which negatively impacts their prognosis. CD31 and D2-40 have recently been suggested to be predictors of breast cancer prognosis, but their...
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Correlations of nasal responses to leukotriene D4 and histamine nasal provocation with quality of life in allergic rhinitis

Zhu Z, Xie Y, Guan W, Gao Y, Xia S, Shi X, Zheng J

BACKGROUND: The symptoms of allergic rhinitis (AR) greatly affect the quality of life (QoL) in the patients with AR. The correlations of nasal response to leukotriene D4 (LTD4) and histamine...
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Protection of chickens against infectious bronchitis virus with a multivalent DNA vaccine and boosting with an inactivated vaccine

Yan F, Zhao Y, Hu Y, Qiu J, Lei W, Ji W, Li X, Wu Q, Shi X, Li Z

The protective efficacy of DNA plasmids encoding avian infectious bronchitis virus (IBV) S1, N, or M protein was investigated in chickens. Chickens were inoculated monovalently (with plasmid pVAX1-16S1, pVAX1-16M, or...
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Hydrogen sulfide restores cardioprotective effects of remote ischemic preconditioning in aged rats via HIF-1α/Nrf2 signaling pathway

Wang H, Shi X, Cheng L, Han J, Mu J

The present study explored the therapeutic potential of hydrogen sulfide (H2 S) in restoring aging-induced loss of cardioprotective effect of remote ischemic preconditioning (RIPC) along with the involvement of signaling...
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Curcumin protects against the intestinal ischemia-reperfusion injury: involvement of the tight junction protein ZO-1 and TNF-alpha related mechanism

Tian S, Guo R, Wei S, Kong Y, Wei X, Wang W, Shi X, Jiang H

Present study aimed to investigate the eff ect of curcumin-pretreatment on intestinal I/R injury and on intestinal mucosa barrier. Thirty Wistar rats were randomly divided into: sham, I/R, and curcumin...
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Attenuation Effect of Recovery Sleep for Impaired Reproductive Function in Male Rats by Sleep Deprivation

Zhang W, Shi X, Zhang Y, Liu G, Wu X, Huang H, Jiang H, Zhang X

Purpose The aim of the present study was to test the hypothesis that recovery sleep could counteract the detrimental effects of sleep deprivation (SD) on male rats’ fertility. Materials and Methods Twenty-two rats...
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Hair Growth Promoting Effects of 650 nm Red Light Stimulation on Human Hair Follicles and Study of Its Mechanisms via RNA Sequencing Transcriptome Analysis

Yang K, Tang Y, Ma Y, Liu Q, Huang Y, Zhang Y, Shi X, Zhang L, Zhang Y, Wang J, Zhu Y, Liu W, Tan Y, Lin J, Wu W

Background: Androgenetic alopecia (AGA) leads to thinning of scalp hair and affects 60%~70% of the adult population worldwide. Developing more effective treatments and studying its mechanism are of great significance....
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IL28B Is Associated with Outcomes of Chronic HBV Infection

Shi X, Chi X, Pan Y, Gao Y, Li W, Yang C, Zhong J, Xu D, Zhang M, Minuk G, Jiang J, Niu J

PURPOSE: The role of IL28B gene variants and expression in hepatitis B virus (HBV) infections are not well understood. Here, we evaluated whether IL28B gene expression and rs12979860 variations are...
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