- Lack of Toll-like Receptor 4 and 2 Polymorphisms in Korean Patients with Bacteremia
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Yoon HJ, Choi JY, Kim CO, Park YS, Kim MS, Kim YK, Shin SY, Kim JM, Song YG
- KMID: 1713104
- J Korean Med Sci.
- 2006 Dec;21(6):979-982.
- doi: 10.3346/jkms.2006.21.6.979
Toll-like receptors (TLRs) are pattern-recognition receptors that are important in innate immune responses to bacterial infection. The purpose of this study is to describe the prevalence of TLRs genetic variations... -
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- Impact of Glutathione S-Transferase M1 and T1 Gene Polymorphisms on the Smoking-Related Coronary Artery Disease
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Kim SJ, Kim MG, Kim KS, Song JS, Yim SV, Chung JH
- KMID: 1786870
- J Korean Med Sci.
- 2008 Jun;23(3):365-372.
- doi: 10.3346/jkms.2008.23.3.365
Glutathione S-transferase (GST) plays a key role in the detoxification of xenobiotic atherogen generated by smoking. To analyze the effect of GSTM1/T1 gene polymorphisms on the development of smoking-related coronary... -
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- Quantitative Analysis of SMN1 Gene and Estimation of SMN1 Deletion Carrier Frequency in Korean Population based on Real-Time PCR
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Lee TM, Kim SW, Lee KS, Jin HS, Koo SK, Jo I, Kang S, Jung SC
- KMID: 1778571
- J Korean Med Sci.
- 2004 Dec;19(6):870-873.
- doi: 10.3346/jkms.2004.19.6.870
Spinal muscular atrophy (SMA) is an autosomal recessive disorder, caused by homozygous absence of the survival motor neuron gene (SMN1) in approximately 94% of patients. Since most carriers have only... -
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- Clinicopathological Features of Rare BRAF Mutations in Korean Thyroid Cancer Patients
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Cho U, Oh WJ, Bae JS, Lee S, Lee YS, Park GS, Lee YS, Jung CK
- KMID: 2129598
- J Korean Med Sci.
- 2014 Aug;29(8):1054-1060.
- doi: 10.3346/jkms.2014.29.8.1054
The most common BRAF mutation in thyroid cancer is c.1799T>A (p.Val600Glu), and other BRAF mutations are rarely reported. We investigated the clinicopathological features of thyroid cancer with rare BRAF mutations.... -
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- Relationship Between the Extent of Chromosomal Losses and the Pattern of CpG Methylation in Gastric Carcinomas
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Hong SJ, Kim YH, Choi YD, Min KO, Choi SW, Rhyu MG
- KMID: 1781762
- J Korean Med Sci.
- 2005 Oct;20(5):790-805.
- doi: 10.3346/jkms.2005.20.5.790
The extent of unilateral chromosomal losses and the presence of microsatellite instability (MSI) have been classified into high-risk (high- and baseline-level loss) and low-risk (low-level loss and MSI) stem-line genotypes... -
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- Intercellular adhesion molecule-1 polymorphisms in Korean patients with Behcet's disease
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Kim EH, Mok JW, Bang D, Lee ES, Lee SN, Park KS
- KMID: 2157660
- J Korean Med Sci.
- 2003 Jun;18(3):415-418.
- doi: 10.3346/jkms.2003.18.3.415
Intercellular adhesion molecule-1 (ICAM-1) is expressed on vascular endothelial cells and its expression increases during the inflammatory response in patients with active Behcet's disease (BD). The ICAM1 gene mutations are... -
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- Apolipoprotein E Gene Polymorphism and Serum Lipids in Patients with Superficial Fungal Disease
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Tursen U, Kaya TI, Eskandari , Bocekli E, Muslu N, Camdeviren H, Ikizoglu G, Atik U
- KMID: 1734117
- Yonsei Med J.
- 2004 Jun;45(3):375-379.
- doi: 10.3349/ymj.2004.45.3.375
Superficial mycosis, including dermatophytic infections, tinea versicolor, and cutaneous candidiasis is mostly limited to the outer layers of the skin, nails, and mucous membranes. In this study, Apolipoprotein E (ApoE)... -
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- Prevalence of BRCA1 and BRCA2 Mutations in Korean Breast Cancer Patients
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Ahn SH, Hwang UK, Kwak BS, Yoon HS, Ku BK, Kang HJ, Kim JS, Ko BK, Ko CD, Yoon KS, Cho DY, Kim JS, Son BH
- KMID: 1733488
- J Korean Med Sci.
- 2004 Apr;19(2):269-274.
- doi: 10.3346/jkms.2004.19.2.269
The incidence of breast cancer in Korea has been increasing in recent years, such that it is now the most common female cancer. Breast cancer in Korea is characterized by... -
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- Association of Vascular Endothelial Growth Factor Gene Polymorphisms with Susceptibility and Clinicopathologic Characteristics of Colorectal Cancer
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Chae YS, Kim JG, Sohn SK, Cho YY, Ahn BM, Moon JH, Jeon SW, Park JY, Lee IT, Choi GS, Jun SH
- KMID: 1786879
- J Korean Med Sci.
- 2008 Jun;23(3):421-427.
- doi: 10.3346/jkms.2008.23.3.421
Since vascular endothelial growth factor (VEGF) is known to be a potent pro-angiogenic factor, we evaluated the potential association of two VEGF gene polymorphisms (-634G>C and 936C>T) with the susceptibility... -
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- The C677 Mutation in Methylene Tetrahydrofolate Reductase Gene: Correlation with Uric Acid and Cardiovascular Risk Factors in Elderly Korean men
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Hong YS, Lee MJ, Kim KH, Lee SH, Lee YH, Kim BG, Jeong B, Yoon HR, Nishio H, Kim JY
- KMID: 1733478
- J Korean Med Sci.
- 2004 Apr;19(2):209-213.
- doi: 10.3346/jkms.2004.19.2.209
The C677T mutation in the methylene tetrahydrofolate reductase (MTHFR) gene results in elevated homocysteine levels and, presumably, in increased cardiovascular risk. Moreover, elevated homocysteine levels are reportedly associated with high... -
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- GSTM1 and GSTP1 Polymorphisms as Potential Factors for Modifying the Effect of Smoking on Inflammatory Response
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Kim JH, Park SG, Lee KH, Choi JH, Ha EH, Myung SK, Hong YC
- KMID: 1713112
- J Korean Med Sci.
- 2006 Dec;21(6):1021-1027.
- doi: 10.3346/jkms.2006.21.6.1021
Inflammation has been known to be an important underlying condition for development of various diseases including cancer. The aims of this study were to investigate whether tobacco smoke exposure increases... -
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- Association between Promoter Polymorphisms of TFF1, TFF2, and TFF3 and the Risk of Gastric and Diffuse Gastric Cancers in a Korean Population
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Jin EH, Lee SI, Kim J, Seo EY, Lee SY, Hur GM, Shin S, Hong JH
- KMID: 2164496
- J Korean Med Sci.
- 2015 Aug;30(8):1035-1041.
- doi: 10.3346/jkms.2015.30.8.1035
Gastric cancer is one of the most common cancers in the world. The aims of this study were to evaluate the association between polymorphisms in TFF gene family, TFF1, TFF2,... -
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- Association of the Gene Polymorphisms of Platelet Glycoprotein Ia and IIb/IIIa with Myocardial Infarction and Extent of Coronary Artery Disease in the Korean Population
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Park S, Park HY, Park C, Ko YG, Im EK, Jo I, Shin C, Lee JB, Shim WH, Cho SY, Jang Y
- KMID: 1734124
- Yonsei Med J.
- 2004 Jun;45(3):428-434.
- doi: 10.3349/ymj.2004.45.3.428
Platelet membrane receptor glycoproteins (GP) are essential for the platelet activation process, and the genetic polymorphisms in the genes that encode platelet glycoproteins have been proposed to influence the risk... -
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- mRNA Expression and RNA Editing (2451 C-to-U) of IL-12 Receptor beta2 in Adult Atopic Patients
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Kim EJ, Lee WM, Ha JS, Ryoo NH, Jeon DS, Kim JR
- KMID: 1713121
- J Korean Med Sci.
- 2006 Dec;21(6):1070-1074.
- doi: 10.3346/jkms.2006.21.6.1070
Interleukin (IL)-12 activates T helper (Th) 1 cells to produce interferon (IFN)-gamma which inhibits atopic inflammation. IL-12 acts through interaction with its receptor, especially beta2 subunit. In several studies, the... -
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