- Transcription of class II MHC gene by interferon-gamma in FRTL-5 cells
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Lee MS, Lee JO, Kang TW, Lee JH
- KMID: 1421913
- J Korean Med Sci.
- 1992 Sep;7(3):189-192.
- doi: 10.3346/jkms.1992.7.3.189
The intracellular mechanism by which interferon-gamma induces the expression of class II major histocompatibility complex (MHC) antigen in nonlymphoid cells is not clear. The effect of recombinant rat interferon-gamma... -
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- Immunogenetics of the HLA system
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Choo SY
- KMID: 1117730
- Yonsei Med J.
- 1991 Mar;32(1):1-8.
- doi: 10.3349/ymj.1991.32.1.1
The study of the HLA system was primarily initiated to understand the basis for the histocompatibility between recipients and tissue donors. HLA typing methods are being continuously improved and biochemical... -
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- Alterations of HLA class I and II antigen expression in preinvasive, invasive and metastatic cervical cancers
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Ryu KS, Lee YS, Kim BK, Park YG, Kim YW, Hur SY, Kim TE, Kim IK, Kim JW
- KMID: 938877
- Exp Mol Med.
- 2001 Sep;33(3):136-144.
HLA expression is altered in a large variety of human cancers. We performed immunohistochemical staining on tissues from normal, preinvasive, invasive and metastatic cervical cancer tissues using anti-HLA class I... -
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- Analysis of swine leukocyte antigen class I gene profiles and porcine endogenous retrovirus viremia level in a transgenic porcine herd inbred for xenotransplantation research
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Matczyńska D, Sypniewski D, Gałka S, Sołtysik , Loch T, Nowak E, Smorąg Z, Bednarek I
- KMID: 2412129
- J Vet Sci.
- 2018 May;19(3):384-392.
- doi: 10.4142/jvs.2018.19.3.384
Molecular characterization of swine leukocyte antigen (SLA) genes is important for elucidating the immune responses between swine-donor and human-recipient in xenotransplantation. Examination of associations between alleles of SLA class I... -
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- Associations of Moyamoya Patients with HLA Class I and Class II Alleles in the Korean Population
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Han H, Pyo CW, Yoo DS, Huh PW, Cho KS, Kim DS
- KMID: 1086747
- J Korean Med Sci.
- 2003 Dec;18(6):876-880.
- doi: 10.3346/jkms.2003.18.6.876
Moyamoya disease is characterized by progressive cerebrovascular occlusion at the peripheral internal carotid artery and development of abnormal collateral circulation at the cerebral basal region. Although abnormal thrombogenesis, inflammation and... -
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- New insight on immune tolerance from transgenic mouse models
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Lee MS
- KMID: 932124
- J Korean Med Sci.
- 1996 Feb;11(1):1-7.
- doi: 10.3346/jkms.1996.11.1.1
No abstract available. -
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- Delayed allograft rejection by the suppression of class II transactivator
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Kim TW, Choi YM, Seo JN, Kim JH, Suh YH, Chung DH, Jung KC, Oh KI
- KMID: 1094146
- Exp Mol Med.
- 2006 Jun;38(3):210-216.
We examined the effect of class II transactivator (CIITA) down-modulation on allograft rejection. To inhibit the function of CIITA, we constructed a series of CIITA mutants and found one exhibiting... -
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- Association of HLA Class II and Non-HLA Gene Polymorphisms with Disease Susceptibility in Korean Children with Type 1 Diabetes Mellitus
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Jung MH, Suh BK, Kim TG, Shin CH, Lee BC
- KMID: 1568739
- J Korean Soc Pediatr Endocrinol.
- 2004 Dec;9(2):136-144.
Purpose : The main genetic contribution to type 1 diabetes susceptibility is the human leukocyte antigen (HLA) class II gene. Several non-HLA chromosomal regions are also known to be involved.... -
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- Association of HLA-DR and -DQ Genes with Familial Moyamoya Disease in Koreans
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Hong SH, Wang KC, Kim SK, Cho BK, Park MH
- KMID: 2190209
- J Korean Neurosurg Soc.
- 2009 Dec;46(6):558-563.
- doi: 10.3340/jkns.2009.46.6.558
OBJECTIVE: Moyamoya disease (MMD) is an uncommon cerebrovascular disorder, characterized by progressive occlusion at the terminal portion of the internal carotid artery. Incidence of the disease is high in East... -
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- Celiac Disease in a Predisposed Subject (HLA-DQ2.5) with Coexisting Graves' Disease
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Hwang IK, Kim SH, Lee U, Chin SO, Rhee SY, Oh S, Woo JT, Kim SW, Kim YS, Chon S
- KMID: 2407112
- Endocrinol Metab.
- 2015 Mar;30(1):105-109.
- doi: 10.3803/EnM.2015.30.1.105
Celiac disease is an intestinal autoimmune disorder, triggered by ingestion of a gluten-containing diet in genetically susceptible individuals. The genetic predisposition is related to human leukocyte antigen (HLA) class II... -
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- Antigenic distribution of HLA - DRB1 locus in citrus red mite ( Panonychus citri ) - sensitive asthma
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Sohn JW, Kim YY, Kim YK, Oh HB, Lee MH, Chang YS, Jung JW, Jee HS, Cho SH, Min KU
- KMID: 2286035
- J Asthma Allergy Clin Immunol.
- 1999 Oct;19(5):713-719.
BACKGROUND: Specific IgE responses to allergens provide useful models for evaluating the genetic factors that control human immune responses. HLA class II gene products are involved in the antigen presentation of exogenous... -
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- Human Leukocyte Antigen Class II Association with Spontaneous Recovery from Hepatitis B Virus Infection in Koreans: Analysis at the Haplotype Level
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Cho SW, Cheong JY, Ju YS, Oh DH, Suh YJ, Lee KW
- KMID: 1783070
- J Korean Med Sci.
- 2008 Oct;23(5):838-844.
- doi: 10.3346/jkms.2008.23.5.838
It has been speculated that human leukocyte antigen (HLA) alleles are associated with the outcome of hepatitis B virus (HBV) infection although the data obtained from various populations have shown... -
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- Distribution of HLA-DQA1*01, *03, *05 and DQB1*02 Subtypes and the Associated Haplotypes in the Korean Population
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Pyo CW, Chung SY, Hur SS, Kim HJ, Choi JY, Kim YK, Yoo HJ, Choi HB, Kim TG
- KMID: 2150575
- Immune Netw.
- 2003 Jun;3(2):103-109.
- doi: 10.4110/in.2003.3.2.103
BACKGROUND: As all HLA class II genes, the DQ genes show their polymorphic variation mainly in the second exon, which encodes the first extracellular domain of the molecule. PCR-SSOP (Polymerase... -
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- A Korean Pedigree of Paget Bone Disease: Including a Case of Panostotic Paget Bone Disease complicated with Giant Cell Reparative Granuloma
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Jeong ET, Park JH, Kim DH, Jeong BO, Ko KS, Rhee BD
- KMID: 2462184
- J Korean Soc Endocrinol.
- 1995 Dec;10(4):456-466.
The polyglandular autoimmune syndrome designates the dysfunction of endocrine and nonendocrine system involving two or more organs on the basis of an autoimmune mechanism. The autoimmune nature of these diseases... -
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- Prevalence of ICA and anti-GAD, HLA DRB1 / DQA1 / DQB1 Polymorphism in Korean IDDM Patients
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Park YS, Shin JH, Kim JB, Choi WH, Ahn YH, Kim TW, Kim MH, Yang SW, Hwang SD, Rhee HB
- KMID: 2137374
- J Korean Diabetes Assoc.
- 1997 Sep;21(3):289-299.
BACKGROUND: Although the HLA class II genes are cleaily associated with insulin-dependent diabetes mellitus(IDDM) in all ethnic. Groups, considerable variation in the associated genotypes is observed among the different ethnic... -
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- The Role of HLA Class II Gene DQB1 in the Development of Duodenal Ulcer in Helicobacter pylori Infected Patients
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Lee SJ, Chun HJ, Jeen YT, Lee HS, Song CW, Um SH, Lee SW, Choi JH, Kim CD, Ryu HS, Hyun JH, Jo YJ
- KMID: 2038320
- Korean J Gastroenterol.
- 2002 Apr;39(4):254-259.
BACKGROUND/AIMS: Helicobacter pylori (H. pylori) infection is associated with gastroduodenal ulcer and gastric cancer only in a small proportion of infected subjects. Both virulence factors of H. pylori strains and... -
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- Molecular Analysis of HLA Class ll-Associated Susceptibility to Neuroinflammatory Diseases in Korean Children
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Oh HH, Kwon SH, Kim CW, Choe BH, Ko CW, Jung HD, Suh JS, Lee JH
- KMID: 1786823
- J Korean Med Sci.
- 2004 Jun;19(3):426-430.
- doi: 10.3346/jkms.2004.19.3.426
The work was done to study immunogenetic peculiarities of neuroinflammatory diseases among Korean children. A total of 13 children with neuroinflammatory diseases (8 males and 5 females; mean age 4.6+/-2.6... -
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- The Clinical and Immunogenetic Characteristics of Adult - Onset Insulin - Dependent Diabetes Mellitus in Korea
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Lee HC, Song MK, Cha BS, Song YD, Lim SK, Kim KR, Huh KB, Kim DH
- KMID: 2306322
- Korean J Med.
- 1999 Jan;56(1):47-65.
Insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease occurring among genetically susceptible individuals. Although the HLA class II genes and immunological abnormalities are clearly associated with IDDM in all racial groups, there... -
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- Induction of ICAM-1 and HLA-DR expression by IFN-gamma in malignant melanoma cell lines
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Kim JD, Lee JL, Park JH, Lee JM, Kim YH, Kim SJ
- KMID: 1729612
- Yonsei Med J.
- 1995 Feb;36(1):15-25.
- doi: 10.3349/ymj.1995.36.1.15
Two human malignant melanoma cell lines, Malme-3M and SK-Mel-28, were analyzed for their ability to induce the expression of intercellular adhesion molecule 1 (ICAM-1) and human leukocyte antigen (HLA)-DR molecules... -
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