- In silico analysis of putative drug and vaccine targets of the metabolic pathways of Actinobacillus pleuropneumoniae using a subtractive/comparative genomics approach
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Birhanu BT, Lee SJ, Park NH, Song JB, Park SC
- KMID: 2407618
- J Vet Sci.
- 2018 Mar;19(2):188-199.
- doi: 10.4142/jvs.2018.19.2.188
Actinobacillus pleuropneumoniae is a Gram-negative bacterium that resides in the respiratory tract of pigs and causes porcine respiratory disease complex, which leads to significant losses in the pig industry worldwide.... -
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- Computational Analysis of Neighboring Genes on Arabidopsis thaliana Chromosomes 4 and 5: Their Genomic Association as Functional Subunits
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Goh SH, Kim TH, Kim JH, Nam DG, Choi D, Hur CG
- KMID: 1973994
- Genomics Inform.
- 2003 Sep;1(1):40-49.
The genes related to specific events or pathways in bacteria are frequently localized proximate to the genome of their neighbors, as with the structures known as operon, but eukaryotic genes... -
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- Evaluation of Protein Expression in Housekeeping Genes across Multiple Tissues in Rats
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Kim HJ, Na JI, Min BW, Na JY, Lee KH, Lee JH, Lee YJ, Kim HS, Park JT
- KMID: 2277376
- Korean J Pathol.
- 2014 Jun;48(3):193-200.
BACKGROUND: Housekeeping genes, which show constant protein expression patterns between different tissue types, are very important in molecular biological studies as an internal control for protein research. METHODS: The protein expression... -
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- Phylogeny of Flavobacteria Group Isolated from Freshwater Using Multilocus Sequencing Analysis
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Mun S, Lee J, Lee S, Han K, Ahn TY
- KMID: 2166512
- Genomics Inform.
- 2013 Dec;11(4):272-276.
- doi: 10.5808/GI.2013.11.4.272
Sequence analysis of the 16S rRNA gene has been widely used for the classification of microorganisms. However, we have been unable to clearly identify five Flavobacterium species isolated from a... -
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- Mining the Proteome of Fusobacterium nucleatum subsp. nucleatum ATCC 25586 for Potential Therapeutics Discovery: An In Silico Approach
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Habib AM, Islam MS, Sohel M, Mazumder M, Sikder MO, Shahik SM
- KMID: 2366444
- Genomics Inform.
- 2016 Dec;14(4):255-264.
- doi: 10.5808/GI.2016.14.4.255
The plethora of genome sequence information of bacteria in recent times has ushered in many novel strategies for antibacterial drug discovery and facilitated medical science to take up the challenge... -
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- Validation of Housekeeping Genes for Gene Expression Analysis in Glioblastoma Using Quantitative Real-Time Polymerase Chain Reaction
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Aithal MG, Rajeswari
- KMID: 1882006
- Brain Tumor Res Treat.
- 2015 Apr;3(1):24-29.
- doi: 10.14791/btrt.2015.3.1.24
BACKGROUND: Quantitative real-time polymerase chain reaction (qPCR) is the most reliable tool for gene expression studies. Selection of housekeeping genes (HKGs) that are having most stable expression is critical to... -
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- Multidrug resistance-associated protein (MRP) and multidrug resistance (MDR1) gene expression in osteosarcoma and their prognostic significance
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Jung HG, Lee SH, Kim HS
- KMID: 2105711
- J Korean Orthop Assoc.
- 2001 Feb;36(1):1-8.
PURPOSE: The purpose of this study is to evaluate the correlations between the multidrug resistance-associated protein (MRP) and multidrug resistance (MDR1) gene in osteosarcoma, and their prognostic significances by RT-PCR... -
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- Multilocus sequence typing analysis of Pseudomonas aeruginosa isolated from pet Chinese stripe-necked turtles (Ocadia sinensis)
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Wendt M, Heo GJ
- KMID: 2362912
- Lab Anim Res.
- 2016 Dec;32(4):208-216.
- doi: 10.5625/lar.2016.32.4.208
Our research sought to characterize the phylogeny of Pseudomonas aeruginosa isolated from pet Chinese stripe-necked turtles (Ocadia sinensis) to better understand its evolutionary relation to other isolates and increase understanding... -
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- Blood transcriptome resources of chinstrap (Pygoscelis antarcticus) and gentoo (Pygoscelis papua) penguins from the South Shetland Islands, Antarctica
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Kim BM, Jeong J, Jo E, Ahn DH, Kim JH, Rhee JS, Park H
- KMID: 2447795
- Genomics Inform.
- 2019 Mar;17(1):e5.
- doi: 10.5808/GI.2019.17.1.e5
The chinstrap (Pygoscelis antarcticus) and gentoo (P. papua) penguins are distributed throughout Antarctica and the sub-Antarctic islands. In this study, high-quality de novo assemblies of blood transcriptomes from these penguins... -
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- Periodic Methylation Patterns in the Background Mucosa of Gastric Cancer
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Kim SW, Oh JH, Kim TH, Kim JS, Hong SJ
- KMID: 2440655
- Korean J Helicobacter Up Gastrointest Res.
- 2019 Mar;19(1):48-55.
- doi: 10.7704/kjhugr.2019.19.1.48
BACKGROUND/AIMS: Gastrointestinal glandular stem cells renew every 8 years. New stem cells with impeded housekeeping gene methylation have unstable phenotypes and are prone to transform into malignant cells. Age-related changes... -
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- A nonsense PAX6 mutation in a family with congenital aniridia
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Han KH, Lee HJ, Ha IS, Kang HG, Cheong HI
- KMID: 2362243
- Korean J Pediatr.
- 2016 Nov;59(Suppl 1):S1-S4.
- doi: 10.3345/kjp.2016.59.11.S1
Congenital aniridia is a rare ocular malformation that presents with severe hypoplasia of the iris and various ocular manifestations. Most cases of congenital aniridia are known to be related to... -
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- Real-time Polymerase Chain Reaction (PCR) in Microbiology
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Lee MK
- KMID: 2170099
- Infect Chemother.
- 2004 Apr;36(2):105-113.
Real-time polymerase chain reaction (PCR) is based on the detection and quantification of a fluorescent reporter. The signal increases in direct proportion to the amount of PCR product formed during... -
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- The Effect of Elapsed Time on the Quantity of mRNA in Skin: A Study to Evaluate the Potential Forensic Use of mRNA to Determine the Postmortem Interval
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Song HJ, Choi YL, Kang SY, Chae JM
- KMID: 2305474
- Korean J Leg Med.
- 2012 Nov;36(2):151-158.
- doi: 10.7580/KoreanJLegMed.2012.36.2.151
Ribonucleic acid (RNA) has potential use in forensic science for the determination of postmortem interval. We report the first study on serial sampling of messenger RNA (mRNA) from surgical specimens... -
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- The Effects of Baicalein on Osteoclast Differentiation from Bone Marrow Derived Macrophage
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Yun JK, Cheon YH, Kim JY, Kwak SC, Yoon KH, Baek JM, Lee MS, Oh J, Park J
- KMID: 1917128
- Korean J Phys Anthropol.
- 2014 Jun;27(2):91-99.
- doi: 10.11637/kjpa.2014.27.2.91
As prediction of rapidly aging society, bone health is considered increasingly important and received more attention than ever. Bone health is regulated by balancing between bone resorptive osteoclasts and bone... -
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- Molecular typing of uropathogenic Escherichia coli isolated from Korean children with urinary tract infection
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Yun KW, Kim DS, Kim W, Lim IS
- KMID: 2284463
- Korean J Pediatr.
- 2015 Jan;58(1):20-27.
- doi: 10.3345/kjp.2015.58.1.20
PURPOSE: We investigated the molecular types of uropathogenic Escherichia coli (UPEC) by using conventional phylogrouping, multilocus sequence typing (MLST), and fimH genotyping. METHODS: Samples of patients younger than 18 years of... -
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- Effects of Liriopis Tuber Water Extract on RANKL-induced Osteoclast Differentiation
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Park KI, Oh J
- KMID: 1449618
- Korean J Phys Anthropol.
- 2011 Dec;24(4):237-244.
Increased formation and activation of osteoclast lead to unwanted bone resorption. Several natural products which have inhibitory effects on osteoclast differentiation and function are under investigation to prevent and treat... -
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- Application of Infrequent-Restriction-Site Polymerase Reaction (IRS-PCR) to the Molecular Epidemiologic Analysis of Methicillin Resistant Staphylococcus aureus (MRSA)
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Shin NY, Yoo JH, Park C, Lee DG, Choi SM, Kwon JC, Kim SH, Park SH, Choi JH
- KMID: 2285012
- Infect Chemother.
- 2011 Oct;43(5):396-405.
- doi: 10.3947/ic.2011.43.5.396
BACKGROUND: We investigated the usefulness of infrequent-restriction-site polymerase chain reaction (IRS-PCR) compared with pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST) on the molecular epidemiologic analysis of methicillin-resistant Staphylococcus... -
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- Gastric Mucosal Atrophy Impedes Housekeeping Gene Methylation in Gastric Cancer Patients
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Oh JH, Rhyu MG, Kim SI, Yun MR, Shin JH, Hong SJ
- KMID: 2437618
- Cancer Res Treat.
- 2019 Jan;51(1):267-279.
- doi: 10.4143/crt.2018.085
PURPOSE: Helicobacter pylori infection induces phenotype-stabilizing methylation and promotes gastric mucosal atrophy that can inhibit CpG-island methylation. Relationship between the progression of gastric mucosal atrophy and the initiation of CpG-island... -
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- Uropathogenic Escherichia coli ST131 in urinary tract infections in children
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Yun KW, Lee MK, Kim W, Lim IS
- KMID: 2387771
- Korean J Pediatr.
- 2017 Jul;60(7):221-226.
- doi: 10.3345/kjp.2017.60.7.221
PURPOSE: Escherichia coli sequence type (ST) 131, a multidrug-resistant clone causing extraintestinal infections, has rapidly become prevalent worldwide. However, the epidemiological and clinical features of pediatric infections are poorly understood.... -
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- Gene Amplification and Overexpression in BPH by Means of One-step Real Time Quantitative PCR
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Kim SW, Lee SJ, Lee JY, Lee CB, Kang SH, Cho YH, Yoon MS
- KMID: 1859357
- Korean J Androl.
- 2001 Dec;19(3):173-180.
PURPOSE: Gene amplification/overexpression of c-erbB2/neu is controversy in BPH by conventional detecting methods. To evaluate the amplification and overexpression of c-erbB2/neu gene in BPH we have used and validated a... -
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