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The role of promoter methylation in Epstein-Barr virus (EBV) microRNA expression in EBV-infected B cell lines

Kim DN, Song YJ, Lee SK

Epstein-Barr virus (EBV) microRNAs (miRNAs) are expressed in EBV-associated tumors and cell lines, but the regulation mechanism of their expression is unclear yet. We investigated whether the expression of EBV...
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Codon optimization of the rabbit hemorrhagic disease virus (RHDV) capsid gene leads to increased gene expression in Spodoptera frugiperda 9 (Sf9) cells

Gao J, Meng C, Chen Z, Li C, Liu G

Rabbit hemorrhagic disease (RHD) is contagious and highly lethal. Commercial vaccines against RHD are produced from the livers of experimentally infected rabbits. Although several groups have reported that recombinant subunit...
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Improved expression by cytomegalovirus promoter/enhancer and behavior of vascular endothelial growth factor gene after myocardial injection of naked DNA

Jeong JO, Byun JH, Jeon ES, Gwon HC, Lim YS, Park JW, Yeo SJ, Lee YJ, Kim SY, Kim DK

  • KMID: 931878
  • Exp Mol Med.
  • 2002 Sep;34(4):278-284.
Direct injection of the vascular endothelial growth factor (VEGF) gene plasmid DNA into the myocardium was shown to induce development of new blood vessels to increase the circulation in...
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Genomic assays for Epstein-Barr virus-positive gastric adenocarcinoma

Gulley ML

A small set of gastric adenocarcinomas (9%) harbor Epstein-Barr virus (EBV) DNA within malignant cells, and the virus is not an innocent bystander but rather is intimately linked to pathogenesis...
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Little role of anti-gB antibodies in neutralizing activity of patient's sera with human cytomegalovirus (HCMV) infection

Park JW, Kim DJ, Kim J, Park CG, Hwang ES, Cha CY

Human cytomegalovirus (HCMV) gB is known to play important roles in cell surface attachment, virion penetration, spread of infection from cell to cell, and provocation of neutralizing antibody. This study...
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Agar gel immunodiffusion analysis using baculovirus-expressed recombinant bovine leukemia virus envelope glycoprotein (gp51/gp30T-)

Lim SI, Jeong W, Tark DS, Yang DK, Kweon CH

Bovine leukemia virus (BLV) envelope glycoprotein (gp51/gp30T-), consisting of BLV gp51 and BLV gp30 that lacked its C-terminal transmembrane domain, was expressed in insect cells under the control of the...
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Phylogenetic characterization of genes encoding for glycoprotein 5 and membrane protein of PRRSV isolate HH08

Wang M, Li G, Yin J, Ren X

A porcine reproductive and respiratory syndrome virus (PRRSV) was obtained from clinic samples. Genes 5 and 6 encoding for the viral glycoprotein 5 and a membrane protein of the PRRSV...
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Comparison of the age-related porcine endogenous retrovirus (PERV) expression using duplex RT-PCR

Moon HJ, Kim HK, Park SJ, Lee CS, Song DS, Kang BK, Park BK

Porcine endogenous retroviruses (PERVs) are members of family Retroviridae, genus Gamma retrovirus, and transmitted by both horizontally and vertically like other endogenous retroviruses (ERVs). PERV was initially described in the...
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Molecular characterization of Japanese encephalitis virus strains prevalent in Chinese swine herds

Zheng H, Shan T, Deng Y, Sun C, Yuan S, Yin Y, Tong G

Japanese encephalitis virus (JEV) is the leading cause of viral encephalitis in Asia and domestic pigs serve as the amplifying hosts. In the present study, the full genomic sequences of...
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Expression of Angiostatin Using DNA-Based Semliki Forest Virus Replicon

Choi YS, Lee JS, Choi YK, Shin KS, Kim HS, Kim CJ

  • KMID: 1101573
  • J Vet Sci.
  • 2002 Mar;3(1):41-45.
Angiogenesis is recognized as a critical factor in the growth of tumor cells and plays a key role in the tumor metastasis. Recent studies for antiangiogenic substances are getting popular....
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Analysis of the precore and core promoter DNA sequence in liver tissues from tients with hepatocellular carcinoma

Cho SW, Shin YJ, Hahm KB, Jin JH, Kim YS, Kim JH, Kim HJ

To investigate the role of mutant hepatitis B virus (HBV) in the development of hepatocellular carcinoma (HCC), 20 patients with HCC were studied for precore and core promoter mutations in...
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A Serine12Stop mutation in PB1-F2 of the 2009 pandemic (H1N1) influenza A: a possible reason for its enhanced transmission and pathogenicity to humans

Ramakrishnan MA, Gramer MR, Goyal SM, Sreevatsan S

As the scientific community scrambles to define the ancestry and lineages of the eight segments of new pandemic H1N1 strain, we looked for unique genetic events in this virus's genome...
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Expression and lytic efficacy assessment of the Staphylococcus aureus phage SA4 lysin gene

Mishra AK, Rawat M, Viswas KN, Abhishek , Kumar S, Reddy M

Treatment of bovine mastitis caused by Staphylococcus (S.) aureus is becoming very difficult due to the emergence of multidrug-resistant strains. Hence, the search for novel therapeutic alternatives has become of...
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Epstein-Barr Virus, Beta-Catenin, and E-cadherin in Gastric Carcinomas

Jung IM, Chung JK, Kim YA, Kim JE, Heo SC, Ahn YJ, Hwang KT, Kim BG, Lee KL, Kim CW, Kim WH, Chang MS

Activated beta-catenin is suggested to inhibit NF-kappaB activation, and we previously demonstrated that NF-kappaB nuclear positivity was more frequent in Epstein-Barr virus (EBV)-infected gastric carcinomas. It is controversial that beta-catenin...
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Characterization of Immortalized Human Corneal Endothelial Cell Line using HPV 16 E6/E7 on Lyophilized Human Amniotic Membrane

Kim HJ, Ryu YH, Ahn JI, Park JK, Kim JC

PURPOSE: To establish the immortalized human corneal endothelial cell line (IHCEn) by transducing human papilloma virus (HPV) 16 E6/E7 oncogenes, and to identify their characteristics when cultivated on a...
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Molecular characterization of a 13-amino acid deletion in VP1 (1D) protein and novel amino acid substitutions in 3D polymerase protein of foot and mouth disease virus subtype A/Iran87

Esmaelizad M, Jelokhani-Niaraki S, Hashemnejad K, Kamalzadeh M, Lotfi M

The nucleotide sequence of the VP1 (1D) and partial 3D polymerase (3Dpol) coding regions of the foot and mouth disease virus (FMDV) vaccine strain A/Iran87, a highly passaged isolate (~150...
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Activation of the intrinsic mitochondrial apoptotic pathway in swine influenza virus-mediated cell death

Choi YK, Kim TK, Kim CJ, Lee JS, Oh SY, Joo HS, Foster DN, Hong KC, You S, Kim H

  • KMID: 1105272
  • Exp Mol Med.
  • 2006 Feb;38(1):11-17.
The mitochondrial pathway of swine influenza virus (SIV)-induced apoptosis was investigated using porcine kidney (PK-15) cells, swine testicle (ST) cells, and HeLa cervical carcinoma cells which are known not to...
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Epidemiological comparisons of codon usage patterns among HIV-1 isolates from Asia, Europe, Africa and the Americas

Ahn I, Son HS

  • KMID: 1115942
  • Exp Mol Med.
  • 2006 Dec;38(6):643-651.
To investigate the genomic properties of HIV-1, we collected 3,081 sequences from the HIV Sequence Database. The sequences were categorized according to sampling region, country, year, subtype, gene name, and...
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An inactivated vaccine to control the current H9N2 low pathogenic avian influenza in Korea

Choi JG, Lee YJ, Kim YJ, Lee EK, Jeong OM, Sung HW, Kim JH, Kwon JH

The H9N2 subtype low pathogenic avian influenza is one of the most prevalent avian diseases worldwide, and was first documented in 1996 in Korea. This disease caused serious economic loss...
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