- Downregulation of regenerating islet-derived 3 alpha (REG3A) in primary human gastric adenocarcinomas
-
Choi B, Suh Y, Kim WH, Christa L, Park J, Bae CD
- KMID: 1091074
- Exp Mol Med.
- 2007 Dec;39(6):796-804.
Gastric carcinoma is considered to be one of the most prevalent cancers worldwide. We have performed differential-display polymerase chain reaction (DD-PCR) in order to compare the gene expression profile of... -
- CITED
-
- Close
- SHARE
-
- Close
- Aberrantly expressed microRNAs in the context of bladder tumorigenesis
-
Lee JY, Ryu DS, Kim WJ, Kim SJ
- KMID: 2426517
- Investig Clin Urol.
- 2016 Jun;57(Suppl 1):S52-S59.
- doi: 10.4111/icu.2016.57.S1.S52
MicroRNAs (miRNAs), small noncoding RNAs 19-22 nucleotides in length, play a major role in negative regulation of gene expression at the posttranscriptional level. Several miRNAs act as tumor suppressors or... -
- CITED
-
- Close
- SHARE
-
- Close
- Down-regulation of human FEN-1 gene expression during differentiation of promyelocytic leukemia cells
-
Kim IS
- KMID: 755017
- Exp Mol Med.
- 1998 Dec;30(4):252-256.
Flap endo/exonuclease-1 (FEN-1) recognizes 5'-flap DNA structures that have been proposed to be important intermediates in DNA replication, repair and recombination, and cleaves the double strand-single strand junction of flap ... -
- CITED
-
- Close
- SHARE
-
- Close
- Rebamipide-induced downregulation of phospholipase D inhibits inflammation and proliferation in gastric cancer cells
-
Kang DW, Min G, Park DY, Hong KW, Min DS
- KMID: 1104382
- Exp Mol Med.
- 2010 Aug;42(8):555-564.
- doi: 10.3858/emm.2010.42.8.056
Rebamipide a gastroprotective drug, is clinically used for the treatment of gastric ulcers and gastritis, but its actions on gastric cancer are not clearly understood. Phospholipase D (PLD) is overexpressed... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of glucose on the expression of c-myc gene in cultured RINm5F cell
-
Kim SW, Yang IM, Kim JW, Kim YS, Kim KW, Choi YK, Suh KS
- KMID: 1421861
- J Korean Med Sci.
- 1991 Sep;6(3):246-250.
- doi: 10.3346/jkms.1991.6.3.246
The study was designed to examine the effect of glucose on the expression of c-myc gene in cultured RINm5F cells. After monolayer culture was established in RPMI 1640 media supplemented... -
- CITED
-
- Close
- SHARE
-
- Close
- Gene Expression Profiling of Breast Cancers with Emphasis of beta-Catenin Regulation
-
Roh MS, Hong SH, Jeong JS, Kwon HC, Kim MC, Cho SH, Yoon JH, Hwang TH
- KMID: 1733489
- J Korean Med Sci.
- 2004 Apr;19(2):275-282.
- doi: 10.3346/jkms.2004.19.2.275
To gain molecular understanding of carcinogenesis of breast cancer, gene expression profiles were analyzed using cDNA microarray representing 4,600 cDNAs in 10 breast cancer samples and the adjacent noncancerous breast... -
- CITED
-
- Close
- SHARE
-
- Close
- Triptolide-induced suppression of phospholipase D expression inhibits proliferation of MDA-MB-231 breast cancer cells
-
Kang DW, Lee JY, Oh DH, Park SY, Woo TM, Kim MK, Park MH, Jang YH, Min DS
- KMID: 756211
- Exp Mol Med.
- 2009 Sep;41(9):678-685.
- doi: 10.3858/emm.2009.41.9.074
In spite of the importance of phospholipase D (PLD) in cell proliferation and tumorigenesis, little is known about the molecules regulating PLD expression. Thus, identification of small molecules inhibiting PLD... -
- CITED
-
- Close
- SHARE
-
- Close
- Bfl-1 Gene Expression in Breast Cancer: Its Relationship with other Prognostic Factors
-
Yoon HS, Hong SH, Kang HJ, Ko BK, Ahn SH, Huh JR
- KMID: 2157626
- J Korean Med Sci.
- 2003 Apr;18(2):225-230.
- doi: 10.3346/jkms.2003.18.2.225
The Bfl-1 gene, which was isolated from human fetal liver and only recently described, is a member of the Bcl-2 gene family. Reverse transcriptase-polymerase chain reaction was performed on RNA... -
- CITED
-
- Close
- SHARE
-
- Close
- Analysis of Gene Expression in Primary Hepatocellular Carcinoma Using Differentially Displayed Reverse Transcriptase Polymerase Chain Reaction
-
Lee YC, Hur W, Choi JE, Piao LS, Hong SW, Bae SH, Choi JY, Yoon SK
- KMID: 1792753
- Korean J Gastroenterol.
- 2009 Jun;53(6):361-368.
- doi: 10.4166/kjg.2009.53.6.361
BACKGROUND/AIMS: The investigation of a specific tumor marker for hepatocellular carcinoma (HCC) is needed to examine the carcinogenesis and to select the patients for treatment options. The aim of this... -
- CITED
-
- Close
- SHARE
-
- Close
- What Is the Significance of Long Non-coding RNA HOX Transcript Antisense Intergenic RNA in Gastric Cancer?
-
Lee SK
- KMID: 1730923
- Korean J Gastroenterol.
- 2014 Feb;63(2):137-139.
- doi: 10.4166/kjg.2014.63.2.137
No abstract available. -
- CITED
-
- Close
- SHARE
-
- Close
- Gene Expression Profiling of Hepatocellular Carcinoma Derived Cancer Stem Like Cell under Hypoxia
-
Choi SH, Lee SW, Ok M, Kim KS, Kim S, Ahn SH
- KMID: 2418927
- Yonsei Med J.
- 2017 Sep;58(5):925-933.
- doi: 10.3349/ymj.2017.58.5.925
PURPOSE: Cancer stem like cells (CSCs), with unlimited self-renewal potential and other stem cell characteristics, occur in several cancers including hepatocellular carcinoma (HCC). Although CSCs can initiate tumors, malignant proliferation,... -
- CITED
-
- Close
- SHARE
-
- Close
- ANT2 suppression by shRNA restores miR-636 expression, thereby downregulating Ras and inhibiting tumorigenesis of hepatocellular carcinoma
-
Jang JY, Lee YS, Jeon YK, Lee K, Jang JJ, Kim CW
- KMID: 2154222
- Exp Mol Med.
- 2013 Jan;45(1):e3.
MicroRNAs (miRNAs) participate in diverse biological functions and carcinogenesis by inhibiting specific gene expression. We previously reported that suppression of adenine nucleotide translocase 2 (ANT2) by using the short hairpin... -
- CITED
-
- Close
- SHARE
-
- Close
- Study of the difference of high and low metastasis cell line's gene expression map and metastasis-related genes of adenoid cystic carcinoma
-
Zhu N, Yang J, Wang Y, Guan X
- KMID: 1109311
- Exp Mol Med.
- 2003 Aug;35(4):243-248.
We searched for metastasis-related genes in adenoid cystic carcinoma by suppression subtractive hybridization analysis of high and low metastasis cell lines. Twelve genes (ten previously identified and two novel sequences)... -
- CITED
-
- Close
- SHARE
-
- Close
- Identification of Up-Regulated Genes in Malignant Glioma with Subtraction Hybridization: Preliminary Screening Studies
-
Cho YJ
- KMID: 1084505
- Yonsei Med J.
- 2008 Apr;49(2):301-310.
- doi: 10.3349/ymj.2008.49.2.301
PURPOSE: This investigation is intended to obtain differentially expressed genes related to human malignant glioma using Subtractive hybridization. MATERIALS AND METHODS: Subtractive hybridization is potentially faster methods for identifying differentially... -
- CITED
-
- Close
- SHARE
-
- Close
- Enhanced expression of the c-myc protooncogene in human intracranial meningiomas
-
Kim JH, Lee SH, Cho KJ, Jang JJ, Hong SI, Lee JO
- KMID: 1421954
- J Korean Med Sci.
- 1993 Feb;8(1):68-72.
- doi: 10.3346/jkms.1993.8.1.68
We examined the alteration and expression of c-myc protooncogene in 11 human intracranial meningiomas using Southern blot, Northern blot and immunohistochemical techniques. Southern blot showed neither amplification nor rearrangement but... -
- CITED
-
- Close
- SHARE
-
- Close
- Hydrogen Peroxide Upregulates TNF-Related Apoptosis-Inducing Ligand (TRAIL) Expression in Human Astroglial Cells, and Augments Apoptosis of T Cells
-
Kwon D, Choi IH
- KMID: 1779506
- Yonsei Med J.
- 2006 Aug;47(4):551-557.
- doi: 10.3349/ymj.2006.47.4.551
The brain is particularly vulnerable to oxygen free radicals, and these radicals have been implicated in the pathology of several neurological disorders. In this study, the modulation of TNF-related apoptosis-inducing... -
- CITED
-
- Close
- SHARE
-
- Close
- Multi-drug resistance (MDR1) gene expression in de novo acute leukemia cells: correlations with CD surface markers and treatment outcome
-
Jiang EZ, Chang YJ, Lee JW, Lee WK, Kim JS, Sohn SK, Lee KB, Suh JS
- KMID: 1038442
- J Korean Med Sci.
- 1998 Dec;13(6):617-622.
- doi: 10.3346/jkms.1998.13.6.617
One important mechanism of drug resistance in acute leukemia is the overexpression of the multi-drug resistance (MDR1) gene that encodes a 170-kDa membrane protein called P-glycoprotein. To estimate the... -
- CITED
-
- Close
- SHARE
-
- Close
- Depletion of mitochondrial DNA up-regulates the expression of MDR1 gene via an increase in mRNA stability
-
Lee W, Choi HI, Kim MJ, Park SY
- KMID: 1103594
- Exp Mol Med.
- 2008 Feb;40(1):109-117.
- doi: 10.3858/emm.2008.40.1.109
The mutation and reduction of mitochondrial DNA (mtDNA) have been suggested as factors in the carcinogenesis. However, whether the depletion of mtDNA induces multidrug resistance in cancer cells has not... -
- CITED
-
- Close
- SHARE
-
- Close
- Genome-wide expression profiling of 8-chloroadenosine- and 8-chloro-cAMP-treated human neuroblastoma cells using radioactive human cDNA microarray.
-
Park GH, Choe JG, Choo HJ, Park YG, Sohn JW, Kim MK
- KMID: 1380226
- Exp Mol Med.
- 2002 Jul;34(3):184-193.
Previous reports raised question as to whether 8-chloro-cyclic adenosine 3,5-monophosphate (8-Cl-cAMP) is a prodrug for its metabolite, 8-Cl-adenosine which exerts growth inhibition in a broad spectrum of cancer cells. The... -
- CITED
-
- Close
- SHARE
-
- Close
- Integrative Analysis of Microarray Data to Reveal Regulation Patterns in the Pathogenesis of Hepatocellular Carcinoma
-
Chen J, Qian Z, Li F, Li J, Lu Y
- KMID: 2412162
- Gut Liver.
- 2017 Jan;11(1):112-120.
- doi: 10.5009/gnl16063
BACKGROUND/AIMS: The integration of multiple profiling data and the construction of a transcriptional regulatory network may provide additional insights into the molecular mechanisms of hepatocellular carcinoma (HCC). The present study... -
- CITED
-
- Close
- SHARE
-
- Close
