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Gene Expression Profiling of Meningioma by cDNA Chip

Park BJ, Kim GK

  • KMID: 2188963
  • J Korean Neurosurg Soc.
  • 2004 Jun;35(6):560-568.
OBJECTIVE: The current progress of the molecular biological study is in the situation of documentation of relation between the tumor development and the gene mutation. We report an analysis of...
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Gene Expression Profiling of 6-MP (6-mercaptopurine) in Liver

Kim HL, Kim HN, Lee EJ

  • KMID: 2166190
  • Genomics Inform.
  • 2006 Mar;4(1):16-22.
The KFDA (Korea Food & Drug Administration) has performed a collaborative toxicogenomics project since 2003. Its aim is to construct a toxicology database of 12 compounds administered to mice at...
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Stem Cell ; New Paradigm in the Era of Genomic Medicine

Park WY, Seo JS

Human stem cells have been isolated from embryos as well as diverse somatic tissues. Much efforts have been made to apply those stem cells for therapeutic purpose. Molecular dissection of...
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Validation of Housekeeping Genes for Gene Expression Analysis in Glioblastoma Using Quantitative Real-Time Polymerase Chain Reaction

Aithal MG, Rajeswari

BACKGROUND: Quantitative real-time polymerase chain reaction (qPCR) is the most reliable tool for gene expression studies. Selection of housekeeping genes (HKGs) that are having most stable expression is critical to...
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Quality assessment of cellular therapies: the emerging role of molecular assays

Stroncek D, Jin P, Ren J, Feng J, Castiello , Civini S, Wang E, Marincola , Sabatino M

Cellular therapies are becoming increasingly important in treating cancer, hematologic malignancies, autoimmune disorders, and damaged tissue. These therapies are becoming more effective and are being used more frequently, but they...
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Gene Expression Profiling of Human Salivary Gland Carcinogenesis with cDNA Microarray

Kim EC, Shin M, Lee DG, Lee JS, Park MH

  • KMID: 2004982
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2001 Jul;23(4):306-323.
No abstract available.
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Genomic Profiling of Liver Cancer

Lee JS

Development of liver cancers is driven largely by genomic alterations that deregulate signaling pathways, influencing growth and survival of cancer cells. Because of the hundreds or thousands of genomic/epigenomic alterations...
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Molecular Subtypes of Primary Glioblastoma Identified by Gene Expression Profiling

Choe GY, Paul SM

  • KMID: 2275565
  • Korean J Pathol.
  • 2002 Oct;36(5):328-337.
BACKGROUND: The over-expression of the epidermal growth factor receptor (EGFR) occurs in nearly 50% of primary glioblastoma multiforme (GBM). Disruption of multiple signaling pathways is a critical factor in regulating...
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Gene Expression Pattern Analysis via Latent Variable Models Coupled with Topographic Clustering

Chang JH, Chi SW, Zhang BT

  • KMID: 1973993
  • Genomics Inform.
  • 2003 Sep;1(1):32-39.
We present a latent variable model-based approach to the analysis of gene expression patterns, coupled with topographic clustering. Aspect model, a latent variable model for dyadic data, is applied to...
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Microarray Analysis of Multiple Gene Expression in Intestinal Metaplasia and Atrophic Gastritis

Choi SR

  • KMID: 1112546
  • Korean J Gastroenterol.
  • 2007 Apr;49(4):260-262.
No abstract availble.
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TRAPR: R Package for Statistical Analysis and Visualization of RNA-Seq Data

Lim JH, Lee SY, Kim JH

High-throughput transcriptome sequencing, also known as RNA sequencing (RNA-Seq), is a standard technology for measuring gene expression with unprecedented accuracy. Numerous bioconductor packages have been developed for the statistical analysis...
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Analysis of Disease Progression-Associated Gene Expression Profile in Fibrillin-1 Mutant Mice: New Insight into Molecular Pathogenesis of Marfan Syndrome

Kim KL, Choi C, Suh W

  • KMID: 2170654
  • Biomol Ther.
  • 2014 Mar;22(2):143-148.
Marfan syndrome (MFS) is a dominantly inherited connective tissue disorder caused by mutations in the gene encoding fibrillin-1 (FBN1) and is characterized by aortic dilatation and dissection, which is the...
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Gene Expression Profiling in C57BL/6 Mice Treated with the Anorectic Drugs Sibutramine and Phendimetrazine and Their Mechanistic Implications

Ko MJ, Choi HS, Ahn JI, Kim SY, Jeong HS, Chung HJ

  • KMID: 2166406
  • Genomics Inform.
  • 2008 Sep;6(3):117-125.
Recently, obesity has become a worldwide public health concern and the use of anorectic drugs has drastically increased. In this study, sibutramine and phendimetrazine, representative marketed anorectics, were repeatedly administered...
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Gene expression profiling of papillary thyroid carcinomas in Korean patients by oligonucleotide microarrays

Chung KW, Kim SW, Kim SW

  • KMID: 2324821
  • J Korean Surg Soc.
  • 2012 May;82(5):271-280.
PURPOSE: The incidence of papillary thyroid carcinomas (PTCs) is rapidly increasing in Korea. Analyzing the gene expression profiling (GEP) of PTCs will facilitate the advent of new methods in diagnosis,...
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Estrogenic activity of zinc pyrithione: an in vivo and in vitro study

Yoon KS, Youn N, Gu H, Kwack SJ

Zinc pyrithione (ZP) is commonly used to prevent dandruff and seborrheic dermatitis. Many consumers are exposed daily to high doses of ZP, causing serious concerns about its toxicity. The reproductive...
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Molecular subtypes and imaging phenotypes of breast cancer

Cho N

During the last 15 years, traditional breast cancer classifications based on histopathology have been reorganized into the luminal A, luminal B, human epidermal growth factor receptor 2 (HER2), and basal-like...
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Comparison of oligonucleotide-microarray and serial analysis of gene expression (SAGE) in transcript profiling analysis of megakaryocytes derived from CD34+ cells

Kim HL

  • KMID: 1093620
  • Exp Mol Med.
  • 2003 Oct;35(5):460-466.
For the comprehensive analysis of transcript expression, the array-based hybridization analysis and the serial analysis of gene expression (SAGE) are commonly used platforms. The SAGE is based on a high-throughput...
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Effect of Leukapheresis on Gene Expression Profiles of Donor's Peripheral Blood Mononuclear Cells

Shin JW, Jin P, Stroncek D

BACKGROUND: Leukapheresis has commonly been used to obtain the cell products intended for clinical cell therapy. Hypocalcemia related to citrate toxicity and some circulatory effects such as hypovolemia and...
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DNA Methylation Profiles of Blood Cells Are Distinct between Early-Onset Obese and Control Individuals

Rhee JK, Lee JH, Yang HK, Kim TM, Yoon KH

Obesity is a highly prevalent, chronic disorder that has been increasing in incidence in young patients. Both epigenetic and genetic aberrations may play a role in the pathogenesis of obesity....
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Expression Profiling of Calcium Induced Genes in Cultured Human Keratinocytes

Lee JS, Kim MR, Kim NS, Kim YS, Yang JM, Cho AY, Lee Y, Kim CD, Lee JH

Terminal differentiation of skin keratinocytes is a vertically directed multi-step process that is tightly controlled by the sequential expression of a variety of genes. To examine the gene expression profile...
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