- Comparison of 16S Ribosomal RNA Targeted Sequencing and Culture for Bacterial Identification in Normally Sterile Body Fluid Samples: Report of a 10-Year Clinical Laboratory Review
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Yoo IY, Kang OK, Lee MK, Kim YJ, Cho SY, Huh K, Kang CI, Chung DR, Peck KR, Huh HJ, Lee NY
- KMID: 2457495
- Ann Lab Med.
- 2020 Jan;40(1):63-67.
- doi: 10.3343/alm.2020.40.1.63
As 16S ribosomal RNA (rRNA)-targeted sequencing can detect DNA from non-viable bacteria, it can be used to identify pathogens from clinical samples even in patients pretreated with antibiotics. We compared... -
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- Relationship of Oral Bacterial Load Over One Year of Smoking Cessation
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Kim S, Seo MS, Hwang SJ
- KMID: 2469736
- J Dent Hyg Sci.
- 2019 Dec;19(4):213-219.
- doi: 10.17135/jdhs.2019.19.4.213
BACKGROUND: Smoking exerts an adverse effect on the periodontal tissue by reorganizing the ecosystem of oral microorganisms and is considered to be an important factor in the development of periodontal... -
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- Antimicrobial effect of toothbrush with light emitting diode on dental biofilm attached to zirconia surface: an in vitro study
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Park JH, Kim YG, Um HS, Lee SY, Lee JK, Chang BS
- KMID: 2463625
- J Dent Rehabil Appl Sci.
- 2019 Sep;35(3):160-169.
- doi: 10.14368/jdras.2019.35.3.160
PURPOSE: The purpose of this study was to evaluate the antimicrobial effects of a toothbrush with light-emitting diodes (LEDs) on periodontitis-associated dental biofilm attached to a zirconia surface by static... -
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- Prognostic Impact of Fusobacterium nucleatum Depends on Combined Tumor Location and Microsatellite Instability Status in Stage II/III Colorectal Cancers Treated with Adjuvant Chemotherapy
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Oh HJ, Kim JH, Bae JM, Kim HJ, Cho NY, Kang GH
- KMID: 2437577
- J Pathol Transl Med.
- 2019 Jan;53(1):40-49.
- doi: 10.4132/jptm.2018.11.29
BACKGROUND: This study aimed to investigate the prognostic impact of intratumoral Fusobacterium nucleatum in colorectal cancer (CRC) treated with adjuvant chemotherapy. METHODS: F. nucleatum DNA was quantitatively measured in a total... -
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- Effect of Various Agents on Oral Bacterial Phagocytosis in THP-1 Cells
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Song Y, Lee HA, Na HS, Chung J
- KMID: 2437339
- Int J Oral Biol.
- 2018 Dec;43(4):217-222.
- doi: 10.11620/IJOB.2018.43.4.217
Phagocytosis is a fundamental process in which phagocytes capture and ingest foreign particles including pathogenic bacteria. Several oral pathogens have anti-phagocytic strategies, which allow them to escape from and survive... -
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- Effect of Natural Extracts on Oral Care Probiotics Weissella cibaria CMU and Periodontal Pathogens
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Yeu JE, Kim HJ, Kang MS
- KMID: 2437336
- Int J Oral Biol.
- 2018 Dec;43(4):193-200.
- doi: 10.11620/IJOB.2018.43.4.193
The purpose of this study is to determine if natural extracts could be used as an additive in oral health food made with Weissella cibaria CMU (oraCMU). Natural extracts of... -
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- Real-time PCR quantification of 9 periodontal pathogens in saliva samples from periodontally healthy Korean young adults
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Choi H, Kim E, Kang J, Kim HJ, Lee JY, Choi J, Joo JY
- KMID: 2465391
- J Periodontal Implant Sci.
- 2018 Aug;48(4):261-271.
- doi: 10.5051/jpis.2018.48.4.261
PURPOSE: Few studies have examined periodontal pathogens from saliva samples in periodontally healthy young adults. The purposes of this study were to determine the prevalence of periodontopathic bacteria and to... -
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- Impact of microbiota in colorectal carcinogenesis: lessons from experimental models
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Yu LC, Wei SC, Ni YH
- KMID: 2417646
- Intest Res.
- 2018 Jul;16(3):346-357.
- doi: 10.5217/ir.2018.16.3.346
A role of gut microbiota in colorectal cancer (CRC) growth was first suggested in germ-free rats almost 50 years ago, and the existence of disease-associated bacteria (termed pathobionts) had becoming... -
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- Intestinal microbiota, chronic inflammation, and colorectal cancer
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Park CH, Eun CS, Han DS
- KMID: 2417645
- Intest Res.
- 2018 Jul;16(3):338-345.
- doi: 10.5217/ir.2018.16.3.338
In addition to genetic and epigenetic factors, various environmental factors, including diet, play important roles in the development of colorectal cancer (CRC). Recently, there is increasing interest in the intestinal... -
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- An in vitro model of Fusobacterium nucleatum and Porphyromonas gingivalis in single- and dual-species biofilms
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Tavares LJ, Klein MI, Panariello BHD, Dorigatti de Avila E, Pavarina A
- KMID: 2405406
- J Periodontal Implant Sci.
- 2018 Feb;48(1):12-21.
- doi: 10.5051/jpis.2018.48.1.12
PURPOSE: The goal of this study was to develop and validate a standardized in vitro pathogenic biofilm attached onto saliva-coated surfaces. METHODS: Fusobacterium nucleatum (F. nucleatum) and Porphyromonas gingivalis (P. gingivalis)... -
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- Comparison of periodontitis-associated oral biofilm formation under dynamic and static conditions
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Song WS, Lee JK, Park SH, Um HS, Lee SY, Chang BS
- KMID: 2388109
- J Periodontal Implant Sci.
- 2017 Aug;47(4):219-230.
- doi: 10.5051/jpis.2017.47.4.219
PURPOSE: The purpose of this study was to compare the characteristics of single- and dual-species in vitro oral biofilms made by static and dynamic methods. METHODS: Hydroxyapatite (HA) disks, 12.7 mm... -
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- Comparisons of Gut Microbiota Among Healthy Control, Patients With Conventional Adenoma, Sessile Serrated Adenoma, and Colorectal Cancer
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Yoon H, Kim N, Park JH, Kim YS, Lee J, Kim HW, Choi YJ, Shin CM, Park YS, Lee DH, Jung HC
- KMID: 2400775
- J Cancer Prev.
- 2017 Jun;22(2):108-114.
- doi: 10.15430/JCP.2017.22.2.108
BACKGROUND: Studies on gut microbiota regarding colorectal carcinogenesis, including sessile serrated adenoma (SSA), have been scarce. The aim of this study is to investigate the role of mucosa-associated gut microbiota... -
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- Development of a Novel Subunit Vaccine Targeting Fusobacterium nucleatum FomA Porin Based on In Silico Analysis
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Jeong K, Sao P, Park MJ, Lee H, Kim SH, Rhee JH, Lee SE
- KMID: 2385807
- Int J Oral Biol.
- 2017 Jun;42(2):63-70.
- doi: 10.11620/IJOB.2017.42.2.063
Selecting an appropriate antigen with optimal immunogenicity and physicochemical properties is a pivotal factor to develop a protein based subunit vaccine. Despite rapid progress in modern molecular cloning and recombinant... -
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- Red fluorescence of oral bacteria interacting with Porphyromonas gingivalis
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Kim SY, Woo DH, Lee MA, Kim JS, Lee JH, Jeong SH
- KMID: 2376035
- J Korean Acad Oral Health.
- 2017 Mar;41(1):22-27.
- doi: 10.11149/jkaoh.2017.41.1.22
OBJECTIVES: Dental plaque is composed of 700 bacterial species. It is known that some oral microorganisms produce porphyrin, and thus, they emit red fluorescence when illuminated with blue light at... -
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- Mining the Proteome of Fusobacterium nucleatum subsp. nucleatum ATCC 25586 for Potential Therapeutics Discovery: An In Silico Approach
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Habib AM, Islam MS, Sohel M, Mazumder M, Sikder MO, Shahik SM
- KMID: 2366444
- Genomics Inform.
- 2016 Dec;14(4):255-264.
- doi: 10.5808/GI.2016.14.4.255
The plethora of genome sequence information of bacteria in recent times has ushered in many novel strategies for antibacterial drug discovery and facilitated medical science to take up the challenge... -
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- Effect of fluoride-containing gel on the roughness of a titanium surface and the promotion of bacterial growth
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Kim SJ, Lee JK, Chang BS, Lee SY, Um HS
- KMID: 2162375
- J Dent Rehabil Appl Sci.
- 2016 Mar;32(1):16-23.
- doi: 10.14368/jdras.2016.32.1.16
PURPOSE: The aim of this study was to evaluate whether fluorides at various pH cause changes in the surface roughness of titanium implants that alter the adherence of bacterial biofilms. MATERIALS... -
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- Detection of Bacterial Species in Chronic Periodontitis Tissues at Different Stages of Disease Severity
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Yoon DL, Kim S, Song H, Kim YG, Lee JM, Kim J
- KMID: 2168720
- J Bacteriol Virol.
- 2015 Dec;45(4):364-371.
- doi: 10.4167/jbv.2015.45.4.364
The goal of this research was to determine the relationship between the stage of chronic periodontitis and the presence of six bacterial pathogens (Aggregatibacter actinomycetemcomitans: AA, Fusobacterium nucleatum: FN, Porphyromonas... -
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- Humoral immune responses to periodontal pathogens in the elderly
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Shet U, Oh HK, Chung HJ, Kim YJ, Kim OS, Lim HJ, Shin MH, Lee SW
- KMID: 2212006
- J Periodontal Implant Sci.
- 2015 Oct;45(5):178-183.
- doi: 10.5051/jpis.2015.45.5.178
PURPOSE: Elderly people are thought to be more susceptible to periodontal disease due to reduced immune function associated with aging. However, little information is available on the nature of immune... -
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- Anti-inflammatory, Antioxidant and Antimicrobial Effects of Artemisinin Extracts from Artemisia annua L.
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Kim WS, Choi WJ, Lee S, Kim WJ, Lee DC, Sohn UD, Shin HS, Kim W
- KMID: 2071815
- Korean J Physiol Pharmacol.
- 2015 Jan;19(1):21-27.
- doi: 10.4196/kjpp.2015.19.1.21
The anti-inflammatory, antioxidant, and antimicrobial properties of artemisinin derived from water, methanol, ethanol, or acetone extracts of Artemisia annua L. were evaluated. All 4 artemisinin-containing extracts had anti-inflammatory effects. Of... -
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- Antimicrobial Activity of Mulberry Leaf against Mutans Streptococci and Periodontopathogens
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Park SN, Lim YK, Cho E, Jo E, Park PS, Kook JK
- KMID: 2170788
- Int J Oral Biol.
- 2014 Dec;39(4):201-206.
- doi: 10.11620/IJOB.2014.39.4.201
This study investigated the antimicrobial activity of methanol extract of mulberry leaf against 16 strains of mutans streptococci and four species of periodontopathogens: Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, and... -
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