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Expression of Intracellular Single Chain Antibody Specific to Hepatitis B Virus X Protein

Jin YH, Kim HI, Park S

BACKGROUND: Intracellular antibody specific to hepatitis B virus X protein (HBx) might be useful for studying the role of HBx in hepatocellular carcinogenesis and HBV replication. METHODS: With variable region...
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Eukaryotic Expression of Human Cytomegalovirus ( HCMV ) Glycoprotein H ( gH )

Park CG, Kook YH, Cha CY, Hwang ES, Choi SB, Lee JH, Kim DJ

  • KMID: 2146893
  • J Korean Soc Microbiol.
  • 1999 Aug;34(4):321-326.
Human cytomegalovirus (HCMV) glycoprotein H (gH) is one of target molecules in the human immune response to HCMV infection. This study was performed to rneasure the immune responses to HCMV...
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Herpesviral Interaction with Autophagy

Liang C

Autophagy constitutes a major catabolic hub for the quality control of intracellular entities of eukaryotic cells, and is emerging as an essential part of the host antiviral defense mechanism. However,...
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Infectivity of Orientia tsutsugamushi to Various Eukaryotic Cells and Their Cellular Invasion Mechanism

Ihn KS, Han SH, Kim HR, Seong SY, Kim IS, Choi MS

  • KMID: 1543606
  • J Korean Soc Microbiol.
  • 1999 Oct;34(5):435-443.
Orientia tsutsugamushi is obligate intracellular bacterium that grows within the cytoplasm of the eukaryotic host cells. Therefore capability of the attachment, entry into the host cell and intracellular survival should...
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Viriditoxin Induces G2/M Cell Cycle Arrest and Apoptosis in A549 Human Lung Cancer Cells

Park JH, Noh TH, Wang H, Kim ND, Jung JH

Viriditoxin is a fungal metabolite isolated from Paecilomyces variotii, which was derived from the giant jellyfish Nemopilema nomurai. Viriditoxin was reported to inhibit polymerization of FtsZ, which is a key...
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Autophagy as an Innate Immune Modulator

Oh JE, Lee HK

Autophagy is a fundamental cellular process in eukaryotic cells for maintaining homeostasis by degrading cellular proteins and organelles. Recently, the roles of autophagy have been expanded to immune systems, which...
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Kinesin Spindle Protein Inhibition in Translational Research

Nyamaa B, Kim HK, Jeong YJ, Song IS, Han J

The kinesin superfamily is a class of motor proteins moving along microtubule filaments and playing essential roles in mitosis of eukaryotic cells. In the cancer biology, mitotic activity is an...
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Current Understanding of HMGB1-mediated Autophagy

Kwak MS, Shin JS

Reactive oxygen species (ROS) is an oxidative stress to which cells respond by activating various defense mechanisms or cell death. Autophagy associated with oxidative stress response is a process to...
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Pathogenic Role of Autophagy in Rheumatic Diseases

Choi YJ, Yoo WH

Autophagy is a principle catabolic process mediated by lysosomes in eukaryotic cells. This is an intracellular homeostatic mechanism crucial for degradation in acidic lysosomal compartments of waste components from the...
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Identification of Retroviral Vectors Producing High Viral Titer

Shin YJ, Lenardo MJ, Park TK, Lee KH

  • KMID: 2096737
  • J Korean Soc Virol.
  • 1999 Mar;29(1):33-38.
Retroviral vector provide a highly efficient method for gene transfer into eukaryotic cells. This vector system can be divided into two components; the retroviral vector itself and the retroviral packaging...
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Immunohistochemical comparison of the telomerase expression between low-grade and high-grade gastric dysplasia

Oh YS, Kim HD, Moon SW, Jeong JH, Kim DH, Yang HS, Kim SH, Kim SP, Jeon WJ, Park H, Choi JY, Kim DH, Lee YJ

  • KMID: 1962199
  • Korean J Med.
  • 2007 Apr;72(4):368-375.
BACKGROUND: Telomeres are simple repeats elements located at each end of the chromosomes of eukaryotic cells. The main function of telomeres is to cap the chromosome end and protect it...
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Re-engineering the mitochondrial genomes in mammalian cells

Yoon YG, Koob MD, Yoo YH

Mitochondria are subcellular organelles composed of two discrete membranes in the cytoplasm of eukaryotic cells. They have long been recognized as the generators of energy for the cell and also...
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Genomewide Profiling of Rapamycin Sensitivity in Saccharomyces cerevisiae on Synthetic Medium

Chang YJ, Shin CS, Han D, Kim J, Kim K, Kwon YM, Huh WK

  • KMID: 1806200
  • Genomics Inform.
  • 2010 Dec;8(4):177-184.
The target of rapamycin (TOR) signaling pathway is a conserved pathway that regulates eukaryotic cell growth in response to environmental cues. Chemical genomic approaches that profile rapamycin sensitivity of yeast...
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Significance of Heat Shock Protein 70 and Sulphomucin Expression in Gastric Adenocarcinomas

Choi EA, Jung KH, Oh MG, Chung BO, Lee JH, Bae SH, Ahn WS, Suh JW, Jung CY, Kim DH

  • KMID: 2206525
  • J Korean Surg Soc.
  • 1999 Jul;57(1):47-56.
BACKGROUND: The heat shock proteins (HSPs) are stress-responsive genes present in all species and play a major role in many cellular processes. These proteins are highly conserved molecules whose expression...
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Non-Thermal Atmospheric-Pressure Plasma Possible Application in Wound Healing

Haertel B, von Woedtke T, Weltmann K, Lindequist U

Non-thermal atmospheric-pressure plasma, also named cold plasma, is defined as a partly ionized gas. Therefore, it cannot be equated with plasma from blood; it is not biological in nature. Non-thermal...
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Distribution and Expression of Superoxide Dismutase in Pediatric Tonsils and Adenoid

Yeo SW, Park SN, Kwon YJ, Park SY, Ju YH, Suh BD

  • KMID: 2275679
  • Korean J Otolaryngol-Head Neck Surg.
  • 2001 Jun;44(6):640-645.
BACKGROUND AND OBJECTIVES: B-lymphocytes and other phagocytes which infiltrate into inflammatory sites in pathologic condition are able to make reactive oxygen species such as superoxide free radicals (SFRs) which have...
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Expression of Heat Shock Protein in Cytokine Stimulated PDL Cells and Inflamed Gingival Tissue

Cho IH, Kim DK, You HK, Shin HS, Kim EC

Prokaryotic and eukaryotic cells respond to heat stress and other environmental abuses by synthesizing a small set of stress proteins and by inhibiting post-transcription synthesis of normal proteins. The purpose...
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Identification and Characterization of Protein Arginine Methyltransferase 1 in Acanthamoeba castellanii

Moon EK, Kong HH, Hong Y, Lee HA, Quan FS

Protein arginine methyltransferase (PRMT) is an important epigenetic regulator in eukaryotic cells. During encystation, an essential process for Acanthamoeba survival, the expression of a lot of genes involved in the...
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Proteomic Profiling of Human Small Cell Lung Cancer Cell Line NCI-H211

Cho HY, Kim MK, Yoo YD, Ahn MJ, Jang JS

  • KMID: 1972869
  • Cancer Res Treat.
  • 2003 Dec;35(6):489-496.
PURPOSE: Small cell lung cancer is one of the major causes of death from cancer worldwide. To explore the expressions of global protein in small cell lung cancer cells, a...
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The Effects of Divalant Cation on the Idarubicin-Induced Apoptosis

Choi DY, Oh MT, Oh YG, Kim JD, Park RK

  • KMID: 1979929
  • Korean J Pediatr Hematol Oncol.
  • 2000 Apr;7(1):105-114.
PURPOSE: Zinc ion is critical for the functional and structural integrity of eukaryotic cells and participate in the regulation of apoptosis. In general, zinc inhibits a nuclear endonuclease, thereby...
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