- Use of aglepristone for the treatment of P4 induced insulin resistance in dogs
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Bigliardi , Bresciani , Callegari , Di Ianni F, Morini G, Parmigiani E, Bianchi E
- KMID: 1784648
- J Vet Sci.
- 2014 Jun;15(2):267-271.
- doi: 10.4142/jvs.2014.15.2.267
Insulin resistance (IR) in dogs is suspected when hyperglycemia is present despite administration of insulin doses greater than 1.0 to 1.5 UI/kg. IR is caused by increases in counter regulatory... -
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- Acidic pH-activated Cl- Current and Intracellular Ca2+ Response in Human Keratinocytes
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Park SJ, Choi WW, Kwon OS, Chung JH, Eun HC, Earm YE, Kim SJ
- KMID: 1838356
- Korean J Physiol Pharmacol.
- 2008 Aug;12(4):177-183.
- doi: 10.4196/kjpp.2008.12.4.177
The layers of keratinocytes form an acid mantle on the surface of the skin. Herein, we investigated the effects of acidic pH on the membrane current and [Ca2+](c) of human... -
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- Unexpected effects of pathogens on epithelial Na+ channels
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Kunzelmann K, Beesley A, King N, Karupiah G, Young J, Cook D
- KMID: 1026955
- J Korean Med Sci.
- 2000 Aug;15(Suppl):S59-S60.
- doi: 10.3346/jkms.2000.15.S.S59
No abstract available. -
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- Activation of Lysophosphatidic Acid Receptor Is Coupled to Enhancement of Ca(2+)-Activated Potassium Channel Currents
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Choi SH, Lee BH, Kim HJ, Hwang SH, Lee SM, Nah SY
- KMID: 1429302
- Korean J Physiol Pharmacol.
- 2013 Jun;17(3):223-228.
- doi: 10.4196/kjpp.2013.17.3.223
The calcium-activated K+ (BKCa) channel is one of the potassium-selective ion channels that are present in the nervous and vascular systems. Ca2+ is the main regulator of BKCa channel activation.... -
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- Oxidized Low-density Lipoprotein- and Lysophosphatidylcholine-induced Ca2+ Mobilization in Human Endothelial Cells
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Kim MY, Liang GH, Kim JA, Choi SS, Choi S, Suh SH
- KMID: 2285368
- Korean J Physiol Pharmacol.
- 2009 Feb;13(1):27-32.
- doi: 10.4196/kjpp.2009.13.1.27
The effects of oxidized low-density lipoprotein (OxLDL) and its major lipid constituent lysophosphatidylcholine (LPC) on Ca2+ entry were investigated in cultured human umbilical endothelial cells (HUVECs) using fura-2 fluorescence and... -
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- Signaling Pathway of Lysophosphatidic Acid-Induced Contraction in Feline Esophageal Smooth Muscle Cells
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Nam YS, Suh JS, Song HJ, Sohn UD
- KMID: 1429385
- Korean J Physiol Pharmacol.
- 2013 Apr;17(2):139-147.
- doi: 10.4196/kjpp.2013.17.2.139
Lysolipids such as LPA, S1P and SPC have diverse biological activities including cell proliferation, differentiation, and migration. We investigated signaling pathways of LPA-induced contraction in feline esophageal smooth muscle cells.... -
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- Development of Position Encoding Circuit for a Multi-Anode Position Sensitive Photomultiplier Tube
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Kwon SI, Hong SJ, Ito M, Yoon HS, Lee GS, Sim KS, Rhee JT, Lee DS, Lee JS
- KMID: 2036494
- Nucl Med Mol Imaging.
- 2008 Dec;42(6):469-477.
PURPOSE: The goal of this paper is to present the design and performance of a position encoding circuit for 16 x 16 array of position sensitive multi-anode photomultiplier tube for... -
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- Effects of Histamine on Cultured Interstitial Cells of Cajal in Murine Small Intestine
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Kim BJ, Kwon YK, Kim E, So I
- KMID: 1429386
- Korean J Physiol Pharmacol.
- 2013 Apr;17(2):149-156.
- doi: 10.4196/kjpp.2013.17.2.149
Interstitial cells of Cajal (ICCs) are the pacemaker cells in the gastrointestinal tract, and histamine is known to regulate neuronal activity, control vascular tone, alter endothelial permeability, and modulate gastric... -
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- Dexmedetomidine-induced contraction of isolated rat aorta is dependent on extracellular calcium concentration
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Ok SH, Bae SI, Shim HS, Sohn JT
- KMID: 2236276
- Korean J Anesthesiol.
- 2012 Sep;63(3):253-259.
- doi: 10.4097/kjae.2012.63.3.253
BACKGROUND: Dexmedetomidine is a highly selective alpha2-adrenoceptor agonist that is widely used for sedation and analgesia during the perioperative period. Intravenous administration of dexmedetomidine induces transient hypertension due to vasoconstriction... -
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- Effects of Inositol 1,4,5-triphosphate on Osteoclast Differentiation in RANKL-induced Osteoclastogenesis
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Son A, Kim MS, Jo H, Byun HM, Shin DM
- KMID: 2285437
- Korean J Physiol Pharmacol.
- 2012 Feb;16(1):31-36.
- doi: 10.4196/kjpp.2012.16.1.31
The receptor activator of NF-kappaB ligand (RANKL) signal is an activator of tumor necrosis factor receptor-associated factor 6 (TRAF6), which leads to the activation of NF-kappaB and other signal transduction... -
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- Age-dependent Kisspeptin Effects on the GnRH Neurons in Male and Female Mice
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Bhattarai , Park SA, Yin H, Park SJ, Jeon JG, Chang KW, Lee SY, Ryu PD, Han SK
- KMID: 1479222
- J Korean Endocr Soc.
- 2008 Oct;23(5):302-309.
- doi: 10.3803/jkes.2008.23.5.302
BACKGROUND: The gonadotropin releasing hormone (GnRH) neurons play a pivotal role in the central regulation of fertility. Kisspeptin binds to the G-protein coupled receptor 54 (GPR54) and GPR54 has been... -
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- Endothelin 1 protects HN33 cells from serum deprivation-induced neuronal apoptosis through Ca2+-PKCalpha-ERK pathway
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Park MH, Lee DH
- KMID: 1103592
- Exp Mol Med.
- 2008 Feb;40(1):92-97.
- doi: 10.3858/emm.2008.40.1.92
Endothelins (ETs), which were originally found to be potent vasoactive transmitters, were known to be implicated in nervous system, but the mode of mechanism remains unclear. ETs (ET-1, ET-2, and... -
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- Molecular mechanisms involved in human platelet aggregation by synergistic interaction of platelet-activating factor and 5-hydroxytryptamine.
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Shah BH, Rasheed H, Rahman IH, Shariff AH, Khan FL, Rahman HB, Hanif S, Saeed SA
- KMID: 1457534
- Exp Mol Med.
- 2001 Dec;33(4):226-233.
Our recent studies have shown that co-activation of Gq and Gi proteins by 5-hydroxytryptamine (5-HT) and adrenaline show synergism in human platelet aggregation. This study was conducted to examine the... -
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- Phytosphingosine-1-phosphate stimulates chemotactic migration of L2071 mouse fibroblasts via pertussis toxin-sensitive G-proteins
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Kim MK, Park KS, Lee H, Kim YD, Yun J, Bae YS
- KMID: 1094659
- Exp Mol Med.
- 2007 Apr;39(2):185-194.
Phytosphingosine-1-phosphate (PhS1P) was found to stimulate an intracellular calcium increase via phospholipase C but not pertussis toxin (PTX)- sensitive G-proteins in L2071 mouse fibroblasts. PhS1P also activated ERK and p38... -
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- Interleukin-1beta promotes the expression of monocyte chemoattractant protein-1 in human aorta smooth muscle cells via multiple signaling pathways
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Lim JH, Um HJ, Park JW, Lee IK, Kwon TK
- KMID: 1009397
- Exp Mol Med.
- 2009 Oct;41(10):757-764.
- doi: 10.3858/emm.2009.41.10.082
Monocyte chemoattractant protein-1 (MCP1) plays a key role in monocyte/macrophage infiltration to the sub-endothelial space of the blood vessel wall, which is a critical initial step in atherosclerosis. In this... -
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