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Biomedical significance of endothelial cell specific growth factor, angiopoietin

Koh GY, Kim I, Kwak HJ, Yun MJ, Leem JC

  • KMID: 1093591
  • Exp Mol Med.
  • 2002 Mar;34(1):1-11.
Until recently, vascular endothelial growth factor (VEGF) was the only growth factor proven to be specific and critical for blood vessel formation. Other long-known factors, such as the fibroblast growth...
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Current Concepts in Diabetic Retinopathy

Song SJ, Wong TY

For the past several decades, tremendous efforts have been made to decrease the complications of diabetes, including diabetic retinopathy. New diagnostic modalities like ultrawide field fundus fluorescein angiography and spectral...
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Expression of Vascular Endothelial Growth Factors A,C and D in Gastric Adenocarcinoma

Chung MJ, Lee JW, Yu KH, Yang DH, Jang KY, Moon WS, Kang MJ, Lee DG

  • KMID: 2275426
  • Korean J Pathol.
  • 2005 Apr;39(2):99-105.
BACKGROUND: Vascular endothelial growth factor (VEGF)-C and VEGF-D are novel growth factors that regulate lymphatic vessel growth. This study was designed to examine whether the expression of three VEGF family...
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Intravitreal anti-vascular endothelial growth factor treatment for retinal diseases

Kim M

Vascular endothelial growth factor (VEGF) is a protein secreted by cells to stimulate angiogenesis, a complex biological phenomenon essential for the development of new blood vessels. Aberrant angiogenesis has been...
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Treatment of Exudative Age-Related Macular Degeneration

Jo NC

Age-related macular degeneration (ARMD) is characterized by both primary and secondary damage of macular retinal pigment epithelial cell, resulting in the formation of drusen, choroidal neovascularization, and atrophy of photoreceptors...
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Up-to-date knowledge on age-related macular degeneration

Kim KL, Park SP

Age-related macular degeneration (AMD) is a major cause of central vision loss in developed countries. The incidence of AMD has increased rapidly in Korea. The objective of this article is...
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Expression of Basic Fibroblast Growth Factor(bFGF), Vascular Endothelial Growth Factor(VEGF), and Platelet-Derived Endothelial Cell Growth Factor(PD-ECGF) in Nasal Polyps

Park SK, Heo KW

  • KMID: 1923197
  • Korean J Otolaryngol-Head Neck Surg.
  • 2001 Dec;44(12):1275-1282.
BACKGROUND AND OBJECTIVES : The etiology of polyp is still largely unknown. Vascular remodelling, with local angiogenesis and plasma leakage, could play a role in the growth process of nasal...
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The correlation between serum vascular endothelial growth factor (VEGF) and tumor VEGF receptor 3 in colorectal cancer

Goulart A, Ferreira C, Rodrigues , Coimbra B, Sousa N, Leão P

PURPOSE: Despite plasma biomarkers offering a number of advantages over tissue-based markers, the relationship between serum vascular endothelial growth factor (VEGF) and VEGF receptor (VEGF-R) tumor expression in colorectal cancer...
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New Modalities for the Diagnosis and Treatment of Diabetic Retinopathy

Gye HJ, Song SJ

Over the past decade, significant advances have been made in both the diagnosis and treatment of diabetic retinopathy. Ultrawide field fundus photography and spectral domain optical coherence tomography have allowed...
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Inhibition of Lymphatic Endothelial Growth Factor Receptor in a Murine Model of Oral Squamous Cell Carcinoma

Kye JY, Park YW

  • KMID: 2136910
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2011 Jan;33(1):1-9.
PURPOSE: Tumor associated angiogenesis and/or lymphangiogenesis are known to be linked by VEGFR signaling pathways. These processes are regulated by several growth factors including VEGFR-2, VEGFR-3. E7080 is an orally...
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Effect of Anti-vascular Endothelial Growth Factor Antibody on the Survival of Cultured Retinal Ganglion Cells

Lee JM, Bae HW, Lee SY, Seong GJ, Kim CY

PURPOSE: To investigate the effects of anti-vascular endothelial growth factor (VEGF) antibody on the survival of retinal ganglion cell (RGC)-5 cells differentiated with staurosporine under oxidative stress. METHODS: We used real-time...
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Effects of Vaseular Endothelial Growth Factors on Hair Growth in Vitro

Back SH, Yoon JB, Sim WY, Haw CR

  • KMID: 1548196
  • Korean J Dermatol.
  • 1999 Jan;37(1):23-30.
BACKGROUND: It has been suggested that the regulation of hair growth might involve complex interaction between dermal papilla cells and hair matrix cells. Dermal papilla cells secrete diffusible factors that...
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Review and update for central serous chorioretinopathy

Shin YU

Central serous chorioretinopathy (CSC) is an eye disease that causes serous retinal detachment in the posterior pole of the retina. The pathogenesis of CSC is not fully understood and various...
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Clinical Significance of Vascular Endothelial Growth Factors (VEGF)-C and -D in Resected Non-Small Cell Lung Cancer

Ko YH, Jung CK, Lee MA, Byun JH, Kang JH, Lee KY, Jo KH, Wang YP, Hong YS

  • KMID: 1804615
  • Cancer Res Treat.
  • 2008 Sep;40(3):133-140.
PURPOSE: Lymphatic spread of tumor is an important prognostic factor for patients with non-small cell lung carcinoma (NSCLC). Vascular endothelial growth factor-C (VEGF-C) and VEGF-D play important roles in lymphangiogenesis...
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Expressions of vascular metastasis related factors in murine orthotopic tumor models of salivary glands

Jang JH, Kwon KJ, Park YW

  • KMID: 2005055
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2007 Nov;29(6):499-508.
BACKGROUND AND PURPOSE: Some subtypes of malignant salivary gland tumors such as adenoid cystic carcinoma (ACC) frequently result in distant metastasis of vascular origin, which are main causes of treatment...
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Role of VEGF in Kidney Development, Microvascular Maintenance and Pathophysiology of Renal Disease

Kim BS, Goligorsky MS

  • KMID: 1106138
  • Korean J Intern Med.
  • 2003 Jun;18(2):65-75.
Vascular endothelial growth factor, VEGF, is essential for endothelial cell differentiation (vasculogenesis) and for the sprouting of new capillaries from preexisting vessels (angiogenesis). In addition, there is strong evidence that...
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Anti-Vascular Endothelial Growth Factor Therapy for Choroidal Neovascularization Secondary to Optic Nerve Head Drusen

Park KH

PURPOSE: To describe a patient with optic nerve head drusen who showed improved retinal hemorrhage and visual acuity following intravitreal anti-vascular endothelial growth factor (bevacizumab) injection. CASE SUMMARY: A 53-year-old woman...
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Inhibition of Neointima Formation by Anti-Vascular Endothelial Growth Factor and Receptor-1 Peptides in a Balloon-Injured Rat Carotid Artery

Lee JM, Moon KW, Yoo KD, Her SH, Yoon HJ, Jin SW, Jeon DS, Youn HJ, Chung WS, Seung KB, Kim CM, Kim JH, Choi KB, Hong SJ

BACKGROUND AND OBJECTIVES: Vascular endothelial growth factor (VEGF) is a potent endothelial cell-specific mitogen. This study was undertaken to test the hypothesis that the neointima hyperplasia induced by a balloon...
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Intravitreal injection of anti-vascular endothelial growth factor for patients with various retinal diseases

Kang S

Vascular endothelial growth factor (VEGF-A) is a major regulator of angiogenesis and vascular permeability. VEGF-A plays an important role in a wide variety of retinal diseases. Therefore, intravitreal injection of...
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Prediction of Invasiveness by the Expressions of CD105 (Endoglin), D2-40 and Vascular Endothelial Growth Factors A and D in the Endoscopic Biopsy Tissue of Stomach Cancer Patients

Kim S, Lee TJ, Kim BK, Cha SJ, Park SJ, Chang IT, Park SI

  • KMID: 2324883
  • J Korean Surg Soc.
  • 2007 May;72(5):358-368.
PURPOSE: CD105 (endoglin) has been shown to be a more useful marker to identify the proliferating endothelium involved in tumor angiogenesis than are the panendothelial markers. The monoclonal antibody D2-40...
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