- Transport of Tetraethylammonium in Renal Cortical Endosomes of Cadmium-Intoxicated Rats
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Park HS, Kim KR, Park YS
- KMID: 1614854
- Korean J Physiol Pharmacol.
- 2002 Feb;6(1):21-26.
Effects of cadmium (Cd) intoxication on renal endosomal accumulation of organic cations (OC ) were studied in rats using 14C-tetraethylammnium (TEA) as a substrate. Cd intoxication was induced by s.c.... -
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- Cadmium inhibition of renal endosomal acidification
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Kim MS, Kim KR, Ahn DW, Park YS
- KMID: 1580642
- Korean J Physiol Pharmacol.
- 2000 Feb;4(1):63-72.
Chronic exposure to cadmium (Cd) results in an inhibition of protein endocytosis in the renal proximal tubule, leading to proteinuria. In order to gain insight into the mechanism by which Cd impairs... -
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- Neuronal Functions of ESCRTs
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Lee JA, Gao FB
- KMID: 2165385
- Exp Neurobiol.
- 2012 Mar;21(1):9-15.
- doi: 10.5607/en.2012.21.1.9
The endosomal sorting complexes required for transport (ESCRTs) regulate protein trafficking from endosomes to lysosomes. Recent studies have shown that ESCRTs are involved in various cellular processes, including membrane scission,... -
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- The hydrophobic amino acids involved in the interdomain association of phospholipase D1 regulate the shuttling of phospholipase D1 from vesicular organelles into the nucleus
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Jang YH, Min DS
- KMID: 1506220
- Exp Mol Med.
- 2012 Oct;44(10):571-577.
Phospholipase D (PLD) catalyzes the hydrolysis of phosphatidylcholine to generate the lipid second messenger, phosphatidic acid. PLD is localized in most cellular organelles, where it is likely to play different... -
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- Justicidin A Reduces β-Amyloid via Inhibiting Endocytosis of β-Amyloid Precursor Protein
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Chun YS, Kwon OH, Oh HG, Cho YY, Yang HO, Chung S
- KMID: 2447854
- Biomol Ther.
- 2019 May;27(3):276-282.
- doi: 10.4062/biomolther.2018.112
β-amyloid precursor protein (APP) can be cleaved by α-, and γ-secretase at plasma membrane producing soluble ectodomain fragment (sAPPα). Alternatively, following endocytosis, APP is cleaved by β-, and γ-secretase at... -
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- ATP13A2/PARK9 Deficiency Neither Cause Lysosomal Impairment Nor Alter alpha-Synuclein Metabolism in SH-SY5Y Cells
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Bae EJ, Lee C, Lee HJ, Kim S, Lee SJ
- KMID: 2165541
- Exp Neurobiol.
- 2014 Dec;23(4):365-371.
- doi: 10.5607/en.2014.23.4.365
Parkinson's disease is a multifactorial disorder with several genes linked to the familial types of the disease. ATP13A2 is one of those genes and encode for a transmembrane protein localized... -
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- CD36 (SR-B2) as a Target to Treat Lipid Overload-Induced Cardiac Dysfunction
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Glatz JF, Luiken JJ, Nabben M
- KMID: 2470801
- J Lipid Atheroscler.
- 2020 Jan;9(1):66-78.
- doi: 10.12997/jla.2020.9.1.66
The heart faces the challenge of adjusting the rate of fatty acid uptake to match myocardial demand for energy provision at any given moment, avoiding both too low uptake rates,... -
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- Ribosomal Protein L19 and L22 Modulate TLR3 Signaling
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Yang EJ, Seo JW, Choi IH
- KMID: 2150702
- Immune Netw.
- 2011 Jun;11(3):155-162.
- doi: 10.4110/in.2011.11.3.155
BACKGROUND: Toll-like receptor 3 (TLR3) recognizes double-stranded RNA (dsRNA) and induces inflammation. In this study we attempted to ascertain if there are endogenous host molecules controlling the production of cytokines... -
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- Prognostic Significance of Cathepsin-D Expression in Breast Cancer
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Kwon YT, Jung CJ, Kim YH, Cho SH, Kim SS, Hong SH
- KMID: 2005561
- J Korean Surg Soc.
- 1998 Aug;55(2):176-184.
BACKGROUND: Cathepsin D is an acid optimal protease present in a variety of normal and neoplastic tissues. Cathepsin D is an aspartylendopeptidase which is thought to be important in intracellular... -
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- Cellular uptake of magnetic nanoparticle is mediated through energydependent endocytosis in A549 cells
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Kim JS, Yoon TJ, Yu KN, Noh MS, Woo M, Kim BG, Lee KH, Sohn BH, Park SB, Lee JK, Cho MH
- KMID: 1089477
- J Vet Sci.
- 2006 Dec;7(4):321-326.
- doi: 10.4142/jvs.2006.7.4.321
Biocompatible silica-overcoated magnetic nanoparticles containing an organic fluorescence dye, rhodamine B isothiocyanate (RITC), within a silica shell [50 nm size, MNP@SiO2(RITC)s] were synthesized. For future application of the MNP@SiO2(RITC)s into... -
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- Heat shock protein 70 alters the endosome-lysosomal localization of huntingtin
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Kang BS, Ahn JY, Kim MK, Kim HJ, Kang L, Lim HC, Park KS, Lee JS, Seo JS, Cha CI, Kim SU, Park YJ, Kim M
- KMID: 1103679
- Exp Mol Med.
- 2007 Feb;39(1):38-46.
Huntington's disease is caused by CAG trinucleotide expansions in the gene encoding huntingtin. N- terminal fragments of huntingtin with polyglutamine produce aggregates in the endosome-lysosomal system, where proteolytic fragments of... -
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- Effects of Integrin avB5 and av B53 on the Adenovirus - Mediated Gene Transduction
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Park JY, Joo SY, Jeon HS, Chang HJ, Kam S, Kim IS
- KMID: 2175115
- J Korean Cancer Assoc.
- 2000 Apr;32(2):422-430.
PURPOSE: Human adenovirus, commonly used as a vector for gene therapy, enters host cells by receptor mediated endocytosis. Since integrin av B5 of cell surface promotes endocytosis of adenovirus and subsequent disruption... -
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