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Japan Society of Gynecologic Oncology 2018 guidelines for treatment of uterine body neoplasms

Yamagami W, Mikami M, Nagase S, Tabata T, Kobayashi Y, Kaneuchi M, Kobayashi H, Yamada H, Hasegawa K, Fujiwara H, Katabuchi H, Aoki D

The Fourth Edition of the Guidelines for Treatment of Uterine Body Neoplasm was published in 2018. These guidelines include 9 chapters: 1. Overview of the guidelines, 2. Initial treatment for...
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Risk Factors Associated with Endometrial Pathology in Premenopausal Breast Cancer Patients Treated with Tamoxifen

Lee M, Piao J, Jeon MJ

PURPOSE: To evaluate factors associated with endometrial pathology during tamoxifen use in premenopausal breast cancer (BC) patients. MATERIALS AND METHODS: We reviewed the medical records of premenopausal BC patients treated with...
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Stage II endometrial cancer requires stratification according to uterine risk factor and sentinel lymph node sampling

Ouh YT, Min KJ

No abstract available.
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Survival and recurrence in stage II endometrial cancers in relation to uterine risk stratification after introduction of lymph node resection and omission of postoperative radiotherapy: a Danish Gynecological Cancer Group Study

Ørtoft G, Høgdall C, Hansen ES, Dueholm M

OBJECTIVE: To evaluate survival and recurrence in stage II endometrial cancer in relation to uterine risk stratification. Outcome for stage II was compared before and after the introduction of lymph...
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LAMC1 is a prognostic factor and a potential therapeutic target in endometrial cancer

Kunitomi H, Kobayashi , Wu RC, Takeda T, Tominaga E, Banno K, Aoki D

OBJECTIVE: With the emerging significance of genetic profiles in the management of endometrial cancer, the identification of tumor-driving genes with prognostic value is a pressing need. The LAMC1 gene, encoding...
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Thick “Swiss Cheese” Appearance of Uterine Endometrium in Postmenopausal Women with Different Gynecologic Conditions

Ko Y, Chung J, Lee SR, Kim SH, Chae H, Kang BM

OBJECTIVES: To uncover gynecologic conditions with similar transvaginal sonographic findings of thick uterine endometrium with honeycomb appearance in pre-and postmenopausal women. METHODS: We retrospectively reviewed cases of patients with endometrial tissue...
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A case of endometrial glassy cell carcinoma: a rare entity which necessitates of better understanding

Callegari , Algeri P, Buzzi A, Motta T, Manfredini C, Rota SM

Endometrial glassy cell carcinoma (EGCC) is a rare neoplasm, accounting for 0.5% of the carcinomas in the endometrium, composed of cells with granular eosinophilic or amphophilic cytoplasm, giving it a...
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Endometrial thickness cut-off value by transvaginal ultrasonography for screening of endometrial pathology in premenopausal and postmenopausal women

Park YR, Lee SW, Kim Y, Bae IY, Kim HK, Choe J, Kim YM

OBJECTIVE: To assess the clinical usefulness and diagnostic accuracy of ultrasonographic measurement of endometrial thickness (ET) in women with endometrial hyperplasia or cancer (EH+). METHODS: This retrospective cohort study included 29,995...
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Fertility sparing treatment for early stage endometrial cancer: current situation and new strategy

Ushijima K

No abstract available.
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Clinicopathologic features, treatment, prognosis and prognostic factors of neuroendocrine carcinoma of the endometrium: a retrospective analysis of 42 cases from the Kansai Clinical Oncology Group/Intergroup study in Japan

Matsumoto , Shimokawa , Nasu K, Shikama A, Shiozaki T, Futagami M, Kai K, Nagano H, Mori T, Yano M, Sugino N, Fujimoto E, Yoshioka N, Nakagawa S, Shimada M, Tokunaga H, Yamada Y, Tsuruta T, Tasaki K, Nishikawa , Kuji S, Motohashi , Ito K, Yamada T, Teramoto N

OBJECTIVE: We conducted a retrospective, multi-institutional, collaborative study to accumulate cases of neuroendocrine carcinoma of the endometrium, to clarify its clinicopathologic features, treatment, prognosis and prognostic factors to collate findings...
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Long-term outcomes of progestin plus metformin as a fertility-sparing treatment for atypical endometrial hyperplasia and endometrial cancer patients

Mitsuhashi A, Habu Y, Kobayashi , Kawarai Y, Ishikawa H, Usui H, Shozu M

OBJECTIVE: The present study investigated long-term outcomes of medroxyprogesterone acetate (MPA) plus metformin therapy in terms of control of atypical endometrial hyperplasia (AEH) and endometrial cancer (EC), and post-treatment conception. METHODS:...
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Prognostic value of metabolic tumor volume and total lesion glycolysis from ¹⁸F-FDG PET/CT in lymph node metastases and risk stratification of endometrial carcinoma

Liu DD, Li J, Li X, Xie L, Qin L, Peng F, Cheng MH

OBJECTIVE: To investigate the prognostic value of metabolic tumor volume (MTV) and total lesion glycolysis (TLG), measured by preoperative ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography (¹⁸F-FDG PET/CT), in risk stratification of...
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Preoperative CA-125 in low-grade endometrial cancer: risk stratification and implications for treatment

Kwon JS

No abstract available.
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Lymph-vascular space invasion (LVSI) as a strong and independent predictor for non-locoregional recurrences in endometrial cancer: a Danish Gynecological Cancer Group Study

Ørtoft G, Lausten-Thomsen L, Høgdall C, Hansen ES, Dueholm M

OBJECTIVE: To evaluate the effect of lymph-vascular space invasion (LVSI) on location of recurrences in Danish patients with endometrial cancer. METHODS: This national cohort study (2005–2012) included 4,380 radically operated patients...
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Transperitoneal para-aortic lymphadenectomy by robot assisted laparoscopy in 10 steps

Heinemann , Masquin I, Blache G, Sabiani L, Jauffret C, Houvenaeghel G, Lambaudie

OBJECTIVE: Para-aortic lymphadenectomy was the cornerstone of gynecologic oncology surgery. In endometrial cancer, the quality of para-aortic lymphadenectomy had direct impact on survival of patient. The launch of robot assisted...
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Improved preoperative risk stratification with CA-125 in low-grade endometrial cancer: a multicenter prospective cohort study

Reijnen C, Visser NC, Kasius JC, Boll D, Geomini PM, Ngo H, Van Hamont D, Pijlman BM, Vos MC, Bulten J, Snijders M, Massuger L, Pijnenborg JM

OBJECTIVES: The global obesity epidemic has great impact on the prevalence of low-grade endometrial carcinoma. The preoperative tumor serum marker cancer antigen 125 (CA-125) might contribute to improved identification of...
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Therapeutic efficacy of Mirena in gynecologic disease

Lee JY

The levonorgestrel-releasing intrauterine system (LNG-IUS) was originally developed as a method of contraception and was first marketed in Finland in 1990. In Korea, the only LNG-IUS approved for non-contraceptive use...
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Dietary Intake of Omega-3 fatty acids and Endocrine-related Gynecological Cancer: A Meta-Analysis of Observational Studies

Hoang T, Myung SK, Pham TT

PURPOSE: Previous observational epidemiological studies have reported inconsistent findings on the association between dietary intake of omega-3 fatty acids and endocrine-related gynecological cancer such as ovarian cancer and endometrial cancer....
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The significance of sonographically thickened endometrium in asymptomatic postmenopausal women

Ozelci R, Dilbaz B, Akpınar F, Kınay T, Baser E, Aldemir O, Altınbas

OBJECTIVE: To investigate the correlation between sonographic, hysteroscopic, and pathological findings in postmenopausal asymptomatic patients with sonographically thickened endometrium. METHODS: The records of postmenopausal patients who attended the Menopause Outpatient Clinic...
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The 34th Annual Meeting of the Korean Society of Gynecologic Oncology 2019: meeting report

Yim GW, Suh DH, Kim JW, Kim SC, Kim YT

The 34th Annual Meeting of Korean Society of Gynecologic Oncology (KSGO) was held in Busan, Korea from 26 to 27 April. Around 460 Korean and international clinicians gathered in Busan...
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