- PI3 kinase Signaling in Drosophila
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Chung JK
- KMID: 1515271
- J Korean Soc Endocrinol.
- 2004 Jun;19(3):281-288.
No abstract available. -
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- Cytotoxicological Effect of Tebufenozide, an Insect Growth Regulator (IGR) : Stimulation of Filamentous Actin Reorganization and Enhancement of Hsp27 Expression in Drosophila Kc Cells
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Hwang JN, Jung HJ, Seo YR
- KMID: 1611499
- Korean J Physiol Pharmacol.
- 2004 Dec;8(6):351-354.
The cytotoxicological responses to insect growth regulator (IGR), using tebufenozide as ecdysteroid mimic, were investigated in Drosophila Kc cells. Treatment of Kc cells with tebufenozide showed significant growth inhibition and... -
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- Expression of Expanded Polyglutamine Disease Proteins in Drosophila (Drosophila Polyglutamine Disease Models)
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Shin SM, Paik KH, Jin DK
- KMID: 2278680
- Korean J Pediatr.
- 2005 Apr;48(4):425-432.
PURPOSE: Polyglutamine diseases are a group of diseases caused by the expansion of a polyglutamine tract in the protein. The present study was performed to verify if polyglutamine disease transgenic... -
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- Drosophila melanogaster as a Model for Studying Aspergillus fumigatus
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AL-Maliki , Martinez S, Piszczatowski P, Bennett JW
- KMID: 2401053
- Mycobiology.
- 2017 Dec;45(4):233-239.
- doi: 10.5941/MYCO.2017.45.4.233
Drosophila melanogaster is a useful model organism that offers essential insights into developmental and cellular processes shared with humans, which has been adapted for large scale analysis of medically important... -
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- Defensive Behavior against Noxious Heat Stimuli Is Declined with Aging Due to Decreased Pain-Associated Gene Expression in Drosophila
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Ghimire S, Kim MS
- KMID: 2380340
- Biomol Ther.
- 2015 May;23(3):290-295.
- doi: 10.4062/biomolther.2014.147
Aging is defined as a collective process that alters organism's functional capacity and appearance over the course of life. Apart from an increase in susceptibility to many diseases, aging affects... -
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- Korean Red Ginseng Tonic Extends Lifespan in D. melanogaster
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Kim MS
- KMID: 1502494
- Biomol Ther.
- 2013 May;21(3):241-245.
Aging is the single most important risk factor that increases susceptibility to many forms of diseases. As such, much effort has been put forward to elucidate the mechanisms behind the... -
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- Taste Sensation in Drosophila melanoganster
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Lee Y, Poudel S
- KMID: 2284354
- Hanyang Med Rev.
- 2014 Aug;34(3):130-136.
- doi: 10.7599/hmr.2014.34.3.130
Animals find nutritious foods to survive, while avoiding aversive and toxic chemicals through the chemosensory faculties of olfaction and taste. The olfaction is comparatively well characterized, but the studies of... -
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- Further understanding of fat biology: Lessons from a fat fly
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Hong JW, Park KW
- KMID: 946665
- Exp Mol Med.
- 2010 Jan;42(1):12-20.
- doi: 10.3858/emm.2010.42.1.007
Obesity is a leading risk factor for insulin resistance, hypertension, hyperlipidemia, and cardiovascular complications, collectively referred to as metabolic diseases. Given the prevalence of obesity and its associated medical problems,... -
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- Genomic Organization of ancop Gene for alpha-COP Homolog from Aspergillus nidulans
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Lee HH, Chae SK, Kim JY, Maeng PJ, Park HM
- KMID: 2312327
- Mycobiology.
- 2000 Dec;28(4):171-176.
We have cloned a alpha-COP homolog, ancop, from Aspergillus nidulans by colony hybridization of chromosome specific library using alpha-COP homologous fragment as a probe. The probe DNA was amplified with... -
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- Low-dose Gamma-irradiation Effect on Early Stage Development and Lifespan in Various Strains of Drosophila melanogaster
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Lee JW, Seong KM, Kim CS, Nam SY, Yang KH, Jin YW
- KMID: 2075037
- Korean J Occup Environ Med.
- 2008 Sep;20(3):225-232.
OBJECTIVES: Although ionizing radiation is recognized as being harmful to humans, debate continues regarding the effects of low doses of ionizing radiation. Some studies have reported that low doses of... -
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- The Synergistic Effects of Antimicrobial Peptides on the Growth Inhibition of Salmonella Typhimurium through Imd Pathway in Drosophila Intestine
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Lim YJ, Jo YH, Kim HJ, Park JK
- KMID: 2168681
- J Bacteriol Virol.
- 2013 Jun;43(2):120-130.
- doi: 10.4167/jbv.2013.43.2.120
Some Bacillus species present in fermented foods are regarded as probiotics because of their ability to modulate the prevention of some intestinal infections and the modulation of the inflammatory immune... -
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- Enhancement of Protein Productivity of Recombinant Hepatitis A Virus VP1 in Stably Transfected Drosophila melanogaster S2 Cells
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Jeon HB, Park JH, Lee HH, Kim DH, Lee HY, Shon DH, Kim W, Chung IS
- KMID: 1434775
- J Bacteriol Virol.
- 2012 Mar;42(1):69-75.
- doi: 10.4167/jbv.2012.42.1.69
The effect of DMSO and sodium butyrate on the production of recombinant hepatitis A virus (HAV) capsid protein VP1 was evaluated and optimized in the culture of stably transfected Drosophila... -
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- Optogenetic Rescue of Locomotor Dysfunction and Dopaminergic Degeneration Caused by Alpha-Synuclein and EKO Genes
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Qi C, Varga S, Oh SJ, Lee CJ, Lee D
- KMID: 2376577
- Exp Neurobiol.
- 2017 Apr;26(2):97-103.
- doi: 10.5607/en.2017.26.2.97
α-Synuclein (α-Syn) is a small presynaptic protein and its mutant forms (e.g. A53T) are known to be directly associated with Parkinson's disease (PD). Pathophysiological mechanisms underlying α-Syn-mediated neurodegeneration in PD... -
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- Genetic Toxicity of Ochratoxin A in Chinese Hamster Lung and VERO Cells, ddY Mice, and Drosophila melanogaster
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Park CH, Ho HY, Heo OS, Sohn SJ, Han ES, Kim JW, Eom MO, Kim SH, Kim JS, Ha KW
- KMID: 2099293
- J Korean Soc Microbiol.
- 1998 Oct;33(5):441-450.
Ochratoxin A is a natural contaminant of mouldy food and feed, which is produced by Penicillium and Aspergillus, and is suspected of being one of the etiological agents responsible for... -
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- A Case of Branchio-Oto-Renal Syndrome
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Kim HJ, Yoon YH, Joo JY, Yoon YH
- KMID: 2277274
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2011 Nov;54(11):784-787.
- doi: 10.3342/kjorl-hns.2011.54.11.784
The branchio-oto-renal (BOR) syndrome is a clinically and genetically heterogeneous disease entity which is characterized by the association of preauricular pits, branchial cleft anomaly, hearing loss and various renal anomalies.... -
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- Characterization of the Rho GTPase-Activating Protein RhoGAP68F
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Nahm M, Lee S
- KMID: 2165343
- Exp Neurobiol.
- 2011 Mar;20(1):29-34.
- doi: 10.5607/en.2011.20.1.29
Rho small GTPases control multiple aspects of neuronal morphogenesis by regulating the assembly and organization of the actin cytoskeleton. Although they are negatively regulated by GTPase activating proteins (GAPs), the... -
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- PINK1 and Parkin to control mitochondria remodeling
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Koh H, Chung J
- KMID: 2168872
- Anat Cell Biol.
- 2010 Sep;43(3):179-184.
- doi: 10.5115/acb.2010.43.3.179
Parkinson's disease (PD), one of the most common neurodegenerative diseases, is characterized by movement disorders and a loss of dopaminergic (DA) neurons. PD mainly occurs sporadically, but may also result... -
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- Naked Cuticle Drosophila 1 Expression in Histologic Subtypes of Small Adenocarcinoma of the Lung
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Ahn S, Hwangbo W, Kim H, Kim CH
- KMID: 2277437
- Korean J Pathol.
- 2013 Jun;47(3):211-218.
BACKGROUND: Naked cuticle Drosophila 1 (NKD1) has been related to non-small cell lung cancer in that decreased NKD1 levels have been associated with both poor prognosis and increased invasive quality. METHODS:... -
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- Drosophila Homolog of Human KIF22 at the Autism-Linked 16p11.2 Loci Influences Synaptic Connectivity at Larval Neuromuscular Junctions
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Park SM, Littleton , Park HR, Lee JH
- KMID: 2165576
- Exp Neurobiol.
- 2016 Feb;25(1):33-39.
- doi: 10.5607/en.2016.25.1.33
Copy number variations at multiple chromosomal loci, including 16p11.2, have recently been implicated in the pathogenesis of autism spectrum disorder (ASD), a neurodevelopmental disease that affects 1~3% of children worldwide.... -
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- Targeted Downregulation of kdm4a Ameliorates Tau-engendered Defects in Drosophila melanogaster
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Park SY, Seo J, Chun YS
- KMID: 2455488
- J Korean Med Sci.
- 2019 Aug;34(33):e225.
- doi: 10.3346/jkms.2019.34.e225
BACKGROUND: Tauopathies, a class of neurodegenerative diseases that includes Alzheimer's disease (AD), are characterized by the deposition of neurofibrillary tangles composed of hyperphosphorylated tau protein in the human brain. As... -
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