- Microtubule and Chromatic Organization in Bovine Oocytes following Intracytoplasmic Injection of Spermatozoon, Sperm Head and Tail
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Do JT, Jun SH, Choi JT, Kang YS, Lee BY, Kim SB, Kim NH, Lee HT, Chung KS
- KMID: 2235762
- Korean J Fertil Steril.
- 1997 Dec;24(3):301-309.
SUMMARY: The objective of this study was to determine the microtubule assembly and chromatin configuration during the first cell cycle in bovine oocytes following injection of spermatozoon, sperm head and... -
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- Fertilization and in vitro Development of Bovine Oocytes Following Round Spermatid Injection
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Um JH, Do JT, Kim NH, Park HD, Lee HT, Chung KS
- KMID: 2235730
- Korean J Fertil Steril.
- 1999 Aug;26(2):193-201.
SUMMARY: In this study we determined fertilization processes and developmental ability of porcine oocytes following injection of round spermatid in the presence of artificial activation. Electrical stimulation at 3 h... -
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- A Simple Method for Generating Cerebral Organoids from Human Pluripotent Stem Cells
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Hong YJ, Lee Sb, Choi J, Yoon SH, Do JT
- KMID: 2526741
- Int J Stem Cells.
- 2022 Feb;15(1):95-103.
- doi: 10.15283/ijsc21195
Background and Objectives: In recent years, brain organoid technologies have been the most innovative advance in neural differentiation research. In line with this, we optimized a method to establish cerebral organoids... -
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- Activation of Porcine Oocytes Following Intracytoplasmic Injection of Various Sperm Components and foreign species spermatozoa
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Jun SH, Shin JS, Do JT, Kwon JK, Kim NH, Lee HT, Chung KS
- KMID: 1930531
- Korean J Fertil Steril.
- 1998 Dec;25(3):331-340.
SUMMARY: We determined the incidence of activation, male pronuclear formation and apposition of pronuclei in porcine oocytes following intracytoplasmic injection of various porcine sperm components and foreign species spermatozoa, such... -
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- Embryonic Stem Cells Lacking DNA Methyltransferases Differentiate into Neural Stem Cells that Are Defective in Self-Renewal
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Seo BJ, Hong TK, Yoon SH, Song JH, Uhm SJ, Song H, Hong K, Schöler HR, Do JT
- KMID: 2539620
- Int J Stem Cells.
- 2023 Feb;16(1):44-51.
- doi: 10.15283/ijsc22138
Background and Objectives: DNA methyltransferases (Dnmts) play an important role in regulating DNA methylation during early developmental processes and cellular differentiation. In this study, we aimed to investigate the role... -
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- Alterations and Co-Occurrence of C-MYC, N-MYC, and L-MYC Expression are Related to Clinical Outcomes in Various Cancers
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Lee M, Seok J, Saha SK, Cho S, Jeong Y, Gil M, Kim A, Shin HY, Bae H, Do JT, Kim YB, Cho SG
- KMID: 2542834
- Int J Stem Cells.
- 2023 May;16(2):215-233.
- doi: 10.15283/ijsc22188
Background and Objectives: MYC, also known as an oncogenic reprogramming factor, is a multifunctional transcription factor that maintains induced pluripotent stem cells (iPSCs). Although MYC is frequently upregulated in various... -
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- Neuronal Differentiation of a Human Induced Pluripotent Stem Cell Line (FS-1) Derived from Newborn Foreskin Fibroblasts
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Kwon J, Lee N, Jeon I, Lee HJ, Do JT, Lee DR, Oh SH, Shin DA, Kim A, Song J
- KMID: 1735408
- Int J Stem Cells.
- 2012 Nov;5(2):140-145.
Isolation of induced pluripotent stem cells (iPSCs) from fully differentiated somatic cells has revolutionized existing concepts of cell differentiation and stem cells. Importantly, iPSCs generated from somatic cells of patients... -
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- Suppression of the ERK–SRF axis facilitates somatic cell reprogramming
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Huh S, Song HR, Jeong GR, Jang H, Seo NH, Lee JH, Yi JY, Lee B, Choi HW, Do JT, Kim JS, Lee SH, Jung JW, Lee T, Shim J, Han MK, Lee TH
- KMID: 2440030
- Exp Mol Med.
- 2018 Feb;50(2):e448.
- doi: 10.1038/emm.2017.279
The molecular mechanism underlying the initiation of somatic cell reprogramming into induced pluripotent stem cells (iPSCs) has not been well described. Thus, we generated single-cell-derived clones by using a combination... -
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