- Effect of Empagliflozin, a Selective Sodium-Glucose Cotransporter 2 Inhibitor, on Kidney and Peripheral Nerves in Streptozotocin-Induced Diabetic Rats
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Lee KA, Jin HY, Lee NY, Kim YJ, Park TS
- KMID: 2418722
- Diabetes Metab J.
- 2018 Aug;42(4):338-342.
- doi: 10.4093/dmj.2017.0095
The effect of sodium-glucose cotransporter 2 inhibitors on peripheral nerves and kidneys in diabetes mellitus (DM) remains unexplored. Therefore, this study aimed to explore the effect of empagliflozin in diabetic... -
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- The protective effect of Amomum xanthoides extract against alloxan-induced diabetes through the suppression of NFkappaB activation
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Park BH, Park JW
- KMID: 1085741
- Exp Mol Med.
- 2001 Jun;33(2):64-68.
This study was undertaken to investigate the preventive mechanism of Amomum xanthoides extract against the development of alloxan-induced diabetics of mice. Pretreatment of mice with A. xanthoides extract via intraperitoneum... -
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- Determination of the optimal diabetes duration for bone regeneration experiments in an alloxan-induced diabetic rabbit calvarial defect model
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Jeong SH, Jung BH, Yoo KY, Um HS, Chang BS, Lee JK, Choi WY
- KMID: 2429866
- J Periodontal Implant Sci.
- 2018 Dec;48(6):383-394.
- doi: 10.5051/jpis.2018.48.6.383
PURPOSE: The purpose of this study was to evaluate the optimal diabetes duration for bone regeneration experiments in an alloxan monohydrate (ALX)–induced diabetic rabbit calvarial defect model by evaluating the... -
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- Increased expression of Galphaq protein in the heart of streptozotocin-induced diabetic rats
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Yang JM, Cho CH, Kong KA, Jang IS, Kim HW, Juhnn YS
- KMID: 1029924
- Exp Mol Med.
- 1999 Dec;31(4):179-184.
Heart disease is one of the major cause of death in diabetic patients, but the thogenesis of diabetic cardio-myopathy remains unclear. In this experiment, to sess the significance... -
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- Effect of edaravone in diabetes mellitus-induced nephropathy in rats
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Varatharajan R, Lim LX, Tan K, Tay CS, Teoh YL, Akhtar SS, Rupeshkumar M, Chung I, Abdullah N, Banik U, Dhanaraj S, Balakumar
- KMID: 2371050
- Korean J Physiol Pharmacol.
- 2016 Jul;20(4):333-340.
- doi: 10.4196/kjpp.2016.20.4.333
Edaravone, a synthetic-free radical scavenger, has been reported to reduce ischemia-reperfusion-induced renal injury by improving tubular cell function, and lowering serum creatinine and renal vascular resistance. The present study investigated... -
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- The Effect of Pertussis Vaccine and Cyclosporin on Streptozotocin Induced Diabetic Rats
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Kim DH
- KMID: 1729546
- Yonsei Med J.
- 1987 Jun;28(2):143-151.
- doi: 10.3349/ymj.1987.28.2.143
The injection of streptozotocin(stz) at a high dose (60 mg/kg) into young male rats produces direct beta cell destruction and leads to insulin dependent diabetes (IDD). In contrast the injection... -
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- Effect of nicotinamide on early graft failure following intraportal islet transplantation
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Jung DY, Park JB, Joo SY, Joh JW, Kwon CH, Kwon GY, Kim SJ
- KMID: 1122279
- Exp Mol Med.
- 2009 Nov;41(11):782-792.
- doi: 10.3858/emm.2009.41.11.084
Intraportal islet transplantation (IPIT) may potentially cure Type 1 diabetes mellitus; however, graft failure in the early post-transplantation period presents a major obstacle. In this study, we tested the ability... -
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- Effect of Phosphodiesterase Inhibitor on Diabetic Nephropathy
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Kang SW
- KMID: 1776540
- Korean J Intern Med.
- 2012 Jun;27(2):151-153.
- doi: 10.3904/kjim.2012.27.2.151
No abstract available. -
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- The diabetes-induced functional and distributional changes of the alpha 1-adrenoceptor of the abdominal aorta and distal mesenteric artery from streptozotocin-induced diabetic rats
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Lee JH, Bahk JH, Park SH, Huh J
- KMID: 2092288
- Korean J Anesthesiol.
- 2011 Apr;60(4):272-281.
- doi: 10.4097/kjae.2011.60.4.272
BACKGROUND: The aim of this study was to evaluate the effect of diabetes on the function and distribution of vascular alpha1-adrenoceptors in the abdominal aorta and distal mesenteric artery from... -
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- Time-dependent changes of calbindin D-28K and parvalbumin immunoreactivity in the hippocampus of rats with streptozotocin-induced type 1 diabetes
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Yi SS
- KMID: 1712302
- J Vet Sci.
- 2013 Dec;14(4):373-380.
- doi: 10.4142/jvs.2013.14.4.373
The hippocampus is affected by various stimuli that include hyperglycemia, depression, and ischemia. Calcium-binding proteins (CaBPs) have protective roles in the response to such stimuli. However, little is known about... -
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- The renoprotective effects of pentoxifylline: beyond its role in diabetic nephropathy
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Kapoor S
- KMID: 1776463
- Korean J Intern Med.
- 2013 May;28(3):374-376.
- doi: 10.3904/kjim.2013.28.3.374
No abstract available. -
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- Bone formation around titanium implants in the tibiae of streptozotocin- induced diabetic rats
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Shin SH, Kim JR, Park BS
- KMID: 2184080
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2000 Sep;22(5):522-541.
Use of osseointegrated implants for missing teeth has been widely utilized in clinical dentistry. Although the procedure has been highly successful, there have also been unavoidable failures. The success of... -
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- Streptozotocin Diabetes Attenuates the Effects of Nondepolarizing Neuromuscular Relaxants on Rat Muscles
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Huang L, Chen D, Li S
- KMID: 2285547
- Korean J Physiol Pharmacol.
- 2014 Dec;18(6):461-467.
- doi: 10.4196/kjpp.2014.18.6.461
The hypothesis of this study was that diabetes-induced desensitization of rat soleus (SOL) and extensor digitorum longus (EDL) to non-depolarizing muscle relaxants (NDMRs) depends on the stage of diabetes and... -
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- Sulfuretin protects against cytokine-induced beta-cell damage and prevents streptozotocin-induced diabetes
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Song MY, Jeong GS, Kwon KB, Ka SO, Jang HY, Park JW, Kim YC, Park BH
- KMID: 983955
- Exp Mol Med.
- 2010 Sep;42(9):628-638.
- doi: 10.3858/emm.2010.42.9.062
NF-kappaB activation has been implicated as a key signaling mechanism for pancreatic beta-cell damage. Sulfuretin is one of the main flavonoids produced by Rhus verniciflua, which is reported to inhibit... -
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- Low Dose Radiation Overcomes Diabetes-induced Suppression of Hippocampal Neuronal Cell Proliferation in Rats
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Kang JO, Kim SK, Hong SE, Lee TH, Kim CJ
- KMID: 1778436
- J Korean Med Sci.
- 2006 Jun;21(3):500-505.
- doi: 10.3346/jkms.2006.21.3.500
We investigated the effect of low dose radiation on diabetes induced suppression of neurogenesis in the hippocampal dentate gyrus of rat. After 0.01 Gy, 0.1 Gy, 1 Gy and 10... -
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- Development of ligand-dependent regulatory system and its application to gene therapy of insulin-dependent diabetes mellitus
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Kim JM, Kim SJ, Lee HC, Kim KS
- KMID: 1110122
- Exp Mol Med.
- 2006 Aug;38(4):385-392.
To develop an inducible expression system, the enhanced artificial nuclear receptors and target reporters were constructed. Artificial nuclear receptors were generated by fusing three domains, consisting of DNA-binding domain (DBD)... -
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- Effect of Antioxidants on Myocardial Damage in Streptozotocin-Induced Diabetic Rats
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Koh JH, Ryu KH, Lim SH, Hong KS, Choi YJ, Park SW
- KMID: 1859053
- Korean Circ J.
- 2006 Apr;36(4):261-271.
- doi: 10.4070/kcj.2006.36.4.261
BACKGROUND AND OBJECTIVES: Many diabetic patients suffer from cardiomyopathy, even in the absence of vascular disease. The aim of this study was to see if dietary antioxidant supplementation has an... -
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- Hypoglycemic effects of vanadium on alloxan monohydrate induced diabetic dogs
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Kim JM, Chung JY, Lee SY, Choi EW, Kim MK, Hwang CY, Youn HY
- KMID: 1089489
- J Vet Sci.
- 2006 Dec;7(4):391-395.
- doi: 10.4142/jvs.2006.7.4.391
The hypoglycemic effects after oral administration of vanadium have been studied previously in many species such as rats, mice and even humans. However, there has been no prior report on... -
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- Adenoviral mediated hepatocyte growth factor gene attenuates hyperglycemia and beta cell destruction in overt diabetic mice
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Park MK, Kim DK, Lee HJ
- KMID: 1119330
- Exp Mol Med.
- 2003 Dec;35(6):494-500.
Hepatocyte growth factor (HGF) is a potent mitogen and promoter of proliferation of insulin producing beta cells of pancreatic islets. To study the role of HGF, an adenoviral vector carrying... -
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- The Role of Free Radical in the Pathogenesis of Impotence in Streptozotocin-Induced Diabetic Rats
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Ryu JK, Kim DJ, Lee T, Kang YS, Yoon SM, Suh JK
- KMID: 1779471
- Yonsei Med J.
- 2003 Apr;44(2):236-241.
- doi: 10.3349/ymj.2003.44.2.236
Diabetes is the most common cause of erectile dysfunction (ED). Oxidative stress has been suggested to be a contributory factor in vascular complications of diabetes in various organs. In the... -
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