- Co-Immunization of Plasmid DNA Encoding IL-12 and IL-18 with Bacillus Calmette-Guerin Vaccine against Progressive Tuberculosis
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Jeon BY, Eoh H, Ha SJ, Bang H, Kim SC, Sung YC, Cho SN
- KMID: 1058823
- Yonsei Med J.
- 2011 Nov;52(6):1008-1015.
- doi: 10.3349/ymj.2011.52.6.1008
PURPOSE: Bacillus Calmette-Guerin (BCG) vaccine has widely been used to immunize against tuberculosis, but its protective efficacy is variable in adult pulmonary tuberculosis, while it is not efficiently protective against... -
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- SIRT1 promotes DNA repair activity and deacetylation of Ku70
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Jeong J, Juhn K, Lee H, Kim SH, Min BH, Lee KM, Cho MH, Park GH, Lee KH
- KMID: 1103676
- Exp Mol Med.
- 2007 Feb;39(1):8-13.
Human SIRT1 controls various physiological responses including cell fate, stress, and aging, through deacetylation of its specific substrate protein. In processing DNA damage signaling, SIRT1 attenuates a cellular apoptotic response... -
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- Flow cytometric analysis of DNA ploidy in primary non-small cell carcinoma of the lung in Korea
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Cheon SH, Sohn HY, Chang J, Kim SK, Ko EH, Kim SK, Lee WY, Lee DY, Shin DH, Jeong ET, Chung HT
- KMID: 1758501
- Yonsei Med J.
- 1993 Dec;34(4):365-370.
- doi: 10.3349/ymj.1993.34.4.365
Flow cytometrically determined nuclear DNA content has been measured on 74 formalin-fixed, paraffin embedded specimens of non-small cell carcinoma of the lung. Of the 60 tumors that were successfully analyzed,... -
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- A Korean Patient with Lattice Corneal Dystrophy Type IV with Leu527Arg Mutation in the TGFBI Gene
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Kim J, Lee KA, Kim EK, Lee HK
- KMID: 1792097
- Korean J Ophthalmol.
- 2014 Feb;28(1):83-85.
- doi: 10.3341/kjo.2014.28.1.83
An 87-year-old woman visited our clinic for a scheduled cataract surgery. At the time of preoperative evaluation, slit lamp examination showed lattice-shaped and granular deposits with asymmetrical patterns in the... -
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- A Novel Mutation in the XLRS1 Gene in a Korean Family with X-linked Retinoschisis
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Koh HJ, Jwa NS, Kim SS, Lee SC, Kwon OW
- KMID: 1099074
- Korean J Ophthalmol.
- 2006 Mar;20(1):62-64.
- doi: 10.3341/kjo.2006.20.1.62
PURPOSE: To report a novel missense mutation in the XLRS1 gene in a Korean family with X-linked retinoschisis. METHODS: Observation case report of a family with a proband with... -
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- A Family with Axenfeld-Rieger Syndrome: Report of the Clinical and Genetic Findings
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Yang HJ, Lee YK, Joo CK, Moon JI, Mok JW, Park MH
- KMID: 2363769
- Korean J Ophthalmol.
- 2015 Aug;29(4):249-255.
- doi: 10.3341/kjo.2015.29.4.249
PURPOSE: To describe clinical findings in a Korean family with Axenfeld-Rieger syndrome. METHODS: A retrospective review of clinical data about patients with diagnosed Axenfeld-Rieger syndrome. Five affected members of the family... -
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- A Case of Korean Patient with Macular Corneal Dystrophy Associated with Novel Mutation in the CHST6 Gene
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Lee YK, Chang DJ, Chung SK
- KMID: 1792082
- Korean J Ophthalmol.
- 2013 Dec;27(6):454-458.
- doi: 10.3341/kjo.2013.27.6.454
To report a novel mutation within the CHST6 gene, as well as describe light and electron microscopic features of a case of macular corneal dystrophy. A 59-year old woman with... -
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- Cardiac expression profiles of the naked DNA vectors encoding vascular endothelial growth factor and basic fibroblast growth factor
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Lee JS, Byun J, Kim JM, Kim CY, Kim BM, Chung JH, Jang Y, Kim DK
- KMID: 1089454
- Exp Mol Med.
- 2005 Oct;37(5):447-456.
We investigated expression profiles and biological effects of the naked DNA vectors in the heart. To this end, naked DNA vector was injected into the apex of the beating rat... -
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- Association between Exudative Age-related Macular Degeneration and the G6721T Polymorphism of XRCC7 in Outdoor Subjects
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Saadat I, Vakili-Ghartavol R, Farvardin-Jahromi M, Saadat M
- KMID: 1499679
- Korean J Ophthalmol.
- 2012 Dec;26(6):423-427.
- doi: 10.3341/kjo.2012.26.6.423
PURPOSE: To investigate whether the G6721T polymorphism (rs.7003908) of the non-homologous end-joining DNA repair XRCC7 gene contributes to the development of exudative age-related macular degeneration (ARMD). METHODS: The present case-control study... -
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- Novel LMNA Gene Mutation in a Patient With Atypical Werner's Syndrome
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Doh YJ, Kim HK, Jung ED, Choi SH, Kim JG, Kim BW, Lee IK
- KMID: 1785645
- Korean J Intern Med.
- 2009 Mar;24(1):68-72.
- doi: 10.3904/kjim.2009.24.1.68
Hutchinson-Gilford progeria syndrome (HGPS) and Werner's syndrome are representative types of progeroid syndrome. LMNA (Lamin A/C) gene mutation with atypical Werner's syndrome have recently been reported. Atypical Werner's syndrome with... -
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- Effect of Heat Shock Protein 72 Expression on Etoposide-induced Cell Death of Rat Retinal Ganglion Cells
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Sohn S, Im JE, Kim TE, Kee C
- KMID: 1501796
- Korean J Ophthalmol.
- 2013 Feb;27(1):48-51.
- doi: 10.3341/kjo.2013.27.1.48
PURPOSE: To assess whether the expression of heat shock protein 72 (Hsp72) protects rat retinal ganglion cells (RGC-5) from apoptotic cell death. METHODS: Hsp72 expression in RGC-5 cells transduced with replication-deficient... -
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- Microarray for Genes Associated with Signal Transduction in Diabetic OLETF Keratocytes
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Lee JE, Lee JS, Hwang SH
- KMID: 1101914
- Korean J Ophthalmol.
- 2007 Jun;21(2):111-119.
- doi: 10.3341/kjo.2007.21.2.111
PURPOSE: The purpose of this study was to identify differences in signal transduction gene expression between normal and diabetic keratocytes stimulated with interleukin-1alpha (IL-1alpha) and tumor necrosis factor-alpha (TNF-alpha). ... -
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- Pharmacogenetic Influence of LOC387715/HTRA1 on the Efficacy of Bevacizumab Treatment for Age-Related Macular Degeneration in a Korean Population
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Kang HK, Yoon MH, Lee DH, Chin HS
- KMID: 1499678
- Korean J Ophthalmol.
- 2012 Dec;26(6):414-422.
- doi: 10.3341/kjo.2012.26.6.414
PURPOSE: The purpose of this study was to determine the pharmacogenetic effects of complement factor H (CFH) Y402H, LOC387715 and high-temperature requirement factor A1 (HTRA1) genotypes on the treatment of... -
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- Diagnostic Usefulness of the Janus Kinase 2 Mutation in non BCR/ABL Myeloproliferative Disorders
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Bang SM, Ahn JY, Park J, Yoo SJ, Park SH, Nam EM, Park PW, Seo YH, Cho EK, Shin DB, Lee JH
- KMID: 759854
- Korean J Intern Med.
- 2006 Dec;21(4):219-224.
- doi: 10.3904/kjim.2006.21.4.219
BACKGROUND: We investigated the Janus kinase 2 (JAK2) mutation and its diagnostic value in patients suffering with non BCR/ABL myeloproliferative diseases (nMPD) or other reactive conditions. METHODS: We... -
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