Yonsei Med J.
1993 Dec;34(4):365-370. 10.3349/ymj.1993.34.4.365.
Flow cytometric analysis of DNA ploidy in primary non-small cell carcinoma of the lung in Korea
- Affiliations
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- 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
- 2Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, Korea.
- 3Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
- 4Department of Internal Medicine, Won Kwang University College of Medicine, Iri, Korea.
- 5Department of Immunology, Won Kwang University College of Medicine, Iri, Korea.
- KMID: 1758501
- DOI: http://doi.org/10.3349/ymj.1993.34.4.365
Abstract
- Flow cytometrically determined nuclear DNA content has been measured on 74 formalin-fixed, paraffin embedded specimens of non-small cell carcinoma of the lung. Of the 60 tumors that were successfully analyzed, 32 (53%) were diploid and 28 (47%) were aneuploid. The mean DNA index of aneuploid tumor was 1.5 +/- 0.25, ranging from 1.1 to 2.0. There was no significant correlation between DNA ploidy and the patient's clinical characteristics, histology of tumor, nodal status or tumor stage. Tumor ploidy was not found as a prognostic determinant in non-small cell carcinoma of the lung in this study.
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