- Staurosporine and cytochalasin D induce chondrogenesis by regulation of actin dynamics in different way
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Kim M, Song K, Jin EJ, Sonn J
- KMID: 1389731
- Exp Mol Med.
- 2012 Sep;44(9):521-528.
Actin cytoskeleton has been known to control and/or be associated with chondrogenesis. Staurosporine and cytochalasin D modulate actin cytoskeleton and affect chondrogenesis. However, the underlying mechanisms for actin dynamics regulation... -
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- Morphological Changes of Cultured Rat Hepatocytes Induced by Phalloidin and Cytochalasin D
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Park KH, Kim JB, Ahn ET, Ko JS, Kim JG
- KMID: 2224528
- Korean J Anat.
- 2000 Dec;33(6):665-676.
The microfilaments of hepatocyte are distributed throughout the vicinity of cell membranes, especially numerous around the region of bile canaliculus, and provide the maintenance of cell shape, cellular wall tension,... -
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- Ultrastructural Changes of the Cultured Hepatocytes in Microfilamentous Dysfunction induced by Drugs
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Kim JG, Ko JS, Ahn ET, Park KH
- KMID: 2092700
- Korean J Anat.
- 1999 Oct;32(5):661-671.
To examine the role of actin microfilaments which are located at beneath the plasma membrane, we observed the ultrastructural changes of rat hepatocyte induced by alteration of the microfilamentous integrity.... -
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- The Role of Intracellular Receptor NODs for Cytokine Production by Macrophages Infected with Mycobacterium leprae
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Kang TJ, Chae GT
- KMID: 2150731
- Immune Netw.
- 2011 Dec;11(6):424-427.
- doi: 10.4110/in.2011.11.6.424
The nucleotide-oligomerization domain (NOD) proteins are members of the NOD-like receptor (NLR) family, which are intracellular and cytoplasmic receptors. We analyzed the role of NODs for cytokine production by macrophages... -
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- The effect of microfilament inhibitor on the Cryptosporidium infection in vitro
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Yu JR, Choi SD
- KMID: 1057183
- Korean J Parasitol.
- 2000 Dec;38(4):257-261.
- doi: 10.3347/kjp.2000.38.4.257
This study was focused on the effects of microfilament inhibitor, Cytochalasin D (CD) on the invasiveness of sporozoites of Cryptosporidium spp. into the host cells. MDCK and AGS cell... -
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- Spreading Shape and Area Regulate the Osteogenesis of Mesenchymal Stem Cells
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Zhao Y, Sun Q, Wang S, Huo B
- KMID: 2467050
- Tissue Eng Regen Med.
- 2019 Dec;16(6):573-583.
- doi: 10.1007/s13770-019-00213-y
BACKGROUND: Mesenchymal stem cells (MSCs) have strong self-renewal ability and multiple differentiation potential. Some studies confirmed that spreading shape and area of single MSCs influence cell differentiation, but few studies... -
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- The Effects of Cytoskeletons on the Cultured Human Melanocytes
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Im S, Byeon SW, Park YK, Lee SH
- KMID: 2361454
- Ann Dermatol.
- 1994 Jul;6(2):162-173.
- doi: 10.5021/ad.1994.6.2.162
BACKGROUND: Cytoskeletons, the complex set of protein fibers found in the cytoplasm, have important roles in the movement of cells and subcellular structures and the generation of shapes. Melanocytes have... -
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- Staurosporine Induces ROS-Mediated Process Formation in Human Gingival Fibroblasts and Rat Cortical Astrocytes
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Lee HG, Kim DS, Moon SA, Kang JW, Seo JT
- KMID: 1789366
- Int J Oral Biol.
- 2015 Mar;40(1):27-33.
- doi: 10.11620/IJOB.2015.40.1.027
In the present study, we investigated the effect of staurosporine on the formation of cellular processes in human gingival fibroblasts and rat astrocytes. Staurosporine caused a rapid induction of process... -
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- CD98 activation increases surface expression and clusteringof beta 1 integrins in MCF-7 cells through FAK/Src- and cytoskeleton-independent mechanisms
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Kim SM, Hahn JH
- KMID: 756327
- Exp Mol Med.
- 2008 Jun;40(3):261-270.
- doi: 10.3858/emm.2008.40.3.261
CD98, a disulfide-linked 125-kDa heterodimeric type II transmembrane glycoprotein, regulates beta 1 integrin- mediated cell adhesion. However, the molecular mechanisms underlying CD98-mediated activation of beta 1 integrin are presently unclear.... -
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- CD98 Activation Increases the Invasion of Human Breast Carcinoma MCF-7 Cells
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Kim SM, Kim JM, Jeon JS, Ahn ZS, Kim DY, Suh JS, Park KH, Park JH, Kim DJ, Hahn JH
- KMID: 2283413
- Korean J Phys Anthropol.
- 2007 Sep;20(3):225-233.
CD98, a disulfide-linked 125-kDa heterodimeric type II transmembrane glycoprotein, regulates the func-tions of beta1 integrin, suggesting that it may play a role in tumor cell invasion. In this study, the... -
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- Mechanisms Underlying Enterococcus faecalis-Induced Tumor Necrosis Factor-alpha Production in Macrophages
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Choi EK, Kim DE, Oh WM, Paek YW, Kang IC
- KMID: 1457113
- Int J Oral Biol.
- 2010 Jun;35(2):43-49.
Enterococcus faecalis, a gram-positive bacterium, has been implicated in endodontic infections, particularly in chronic apical periodontitis. Proinflammatory cytokines, including tumor necrosis factor-alpha (TNF-alpha), are involved in the pathogenesis of these... -
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- Aggregatibacter actinomycetemcomitans Strongly Stimulates Endothelial Cells to Produce Monocyte Chemoattractant Protein-1 and Interleukin-8
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Choi EK, Kang MS, Oh BH, Kim SY, Kim SH, Kang IC
- KMID: 1436488
- Int J Oral Biol.
- 2012 Sep;37(3):137-145.
Aggregatibacter actinomycetemcomitans is the most important etiologic agent of aggressive periodontitis and can interact with endothelial cells. Monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8) are chemokines, playing important roles in... -
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- Possibility of involvement of Porphyromonas gingivalis in coronary heart disease
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Lee JY, Park BL, Yun HK, Park EA, Shin EA, Jue SS, Shin JW
- KMID: 2146877
- J Korean Soc Microbiol.
- 2000 Jun;35(3):203-214.
Porphyromonas gingivalis has been implicated in periodontal diseases. Accumulating evidence suggests that cardiovascular disease is the most prevalent medical problem in patients with periodontal diseases. In order to check the possibility that P.... -
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