- Expression of Cyclin A, B1, D1, D3, and E in Non-Small Lung Cancers
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Ha SY, Kim HK, Im JS, Cho HY, Chung DH, An J
- KMID: 2199874
- J Lung Cancer.
- 2012 Jun;11(1):33-37.
- doi: 10.6058/jlc.2012.11.1.33
PURPOSE: Cyclins, and their associated cyclin dependent kinases, regulate progression of the cell cycle through the G1 phase and into the S-phase during the DNA replication process. Cyclin E regulation... -
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- Reduced Expression of Cyclins and Proliferative Indices on the Psoriatic Epidermis after 12 Weeks of Oral Cyclosporin Therapy
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Han SS, Hyun OS, Chang SE, Lee MW, Choi JH, Moon KC, Koh JK
- KMID: 1881992
- Ann Dermatol.
- 2006 Oct;18(2):51-58.
- doi: 10.5021/ad.2006.18.2.51
Cell growth characterized by cell cycle progression is regulated by cyclin-dependent kinase (CDK). CDKs are activated by binding cyclins such as cyclin A, cyclin B, cyclin D1, and cyclin E.... -
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- Effects of DCA on Cell Cycle Proteins in Colonocytes
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Ha YH, Park DG
- KMID: 2198785
- J Korean Soc Coloproctol.
- 2010 Aug;26(4):254-259.
- doi: 10.3393/jksc.2010.26.4.254
PURPOSE: Evidence that indicates bile acid is a promoter of colon cancer exists. Deoxycholic acid (DCA) modifies apoptosis or proliferation by affecting intracellular signaling and gene expression. However, because previous... -
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- Effect of Deoxycholic Acid on the Proliferation and Apoptosis of HCT116 Colon Cancer Cells
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Park DG
- KMID: 2004406
- J Korean Surg Soc.
- 2005 Mar;68(3):211-217.
PURPOSE: Bile acids were considered as a promoting factor for colon cancers. It has been suggested that bile acids could promote cellular proliferation or apoptosis according to their concentration. Therefore,... -
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- Expression Patterns of Ki-67, Cyclin A, and Cyclin D1 during Tooth Development
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Kwon HJ, Yoon KS, Jung HS
- KMID: 1430198
- Korean J Phys Anthropol.
- 2013 Mar;26(1):41-49.
- doi: 10.11637/kjpa.2013.26.1.41
Dental epithelial and mesenchymal cells that form the teeth undergo dynamic changes in cell cycle during tooth development and morphogenesis. Although proliferation has been known as a key event during... -
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- Relationship between the expression of cyclin B1, D1 and the various prognostic factors in ovarian carcinoma
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Kim HY, Kim JW, Kim YT, Kang MH, Kim JH, Kim SH, Kim SW, Yoon BS
- KMID: 2272740
- Korean J Obstet Gynecol.
- 2005 Nov;48(11):2670-2681.
OBJECTIVE: The objective of this study was to evaluate the relationship between the expression of cyclin B1, D1 and the various prognostic factors in ovarian carcinoma. METHODS: In this study, fresh... -
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- Cellular Effects of Troglitazone on YD15 Tongue Carcinoma Cells
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Ta Thi L, Yoo H
- KMID: 2354198
- Int J Oral Biol.
- 2016 Sep;41(3):113-118.
- doi: 10.11620/IJOB.2016.41.3.113
An FDA approved drug for the treatment of type II diabetes, Troglitazone (TRO), a peroxisome proliferator–activated receptor gamma agonist, is withdrawn due to severe idiosyncratic hepatotoxicity. In the search for... -
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- Biochemical characterizations reveal different properties between CDK4/cyclin D1 and CDK2/cyclin A
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Kim DM, Yang K, Yang BS
- KMID: 1093615
- Exp Mol Med.
- 2003 Oct;35(5):421-430.
CDK2 and CDK4 known promoter of cell cycling catalyze phosphorylation of RB protein. Enzyme specificity between two CDKs that work at a different cell cycle phase is not clearly understood.... -
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- The Expression of Hypoxia Inducible Factor-1alpha and Its Correlation with the Expressions of Cyclin A1 and Cyclin B1 and the Clinicopathologic Factors of Uterine Cervical Carcinoma
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Pyo JY, Cho JH, Kim H, Park JP, Kim YT, Cho NH
- KMID: 1472549
- Korean J Pathol.
- 2009 Feb;43(1):13-19.
- doi: 10.4132/KoreanJPathol.2009.43.1.13
BACKGROUND: Hypoxia inducible factor-1alpha(HIF-1alpha) is a transcription factor for various target genes that are involved in adapting cells to hypoxia. It promotes cell proliferation and survival via modulation of such... -
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- CHANGES OF CYCLINS, CYCLIN DEPENDENT KINASES, CYCLIN DEPENDENT KINASE INHIBITORS DURING GLOSSAL DEVELOPMENT IN THE RATS
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Kim HH, Lee SC
- KMID: 2005912
- J Korean Assoc Oral Maxillofac Surg.
- 1997 Nov;23(4):581-596.
The molecular mechanisms that regulate glossal muscle cell cycle and terminal differentiation remain largely unknown. To determine which cyclins, cyclin dependent kinases (CDKs), cyclin dependent kinase inhibitors (CKIs) are important... -
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- Expression of G1 cell cycle related genes in triamcinolone acetonide treated keloid fibroblasts
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Woo SH, Seul JH, Suh SI, Baek WK, Suh MH
- KMID: 1941847
- J Korean Soc Plast Reconstr Surg.
- 1998 Feb;25(2):178-190.
The effect of triamcinolone acetonide(TA) on the expression of Gl related genes was investigated the cultured keloid fibroblast. The addition of TA to the culture medium resulted in growth inhibition... -
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- Expression of Cyclin A and Ki-67 in the Uterine Cervical Carcinoma
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Kim MK, Bae DH, Kim CJ
- KMID: 2244993
- Korean J Gynecol Oncol Colposc.
- 1998 Dec;9(4):464-470.
The cell cycle is the set of events that is responsible for the duplication of the cells. Recent studies indicate that cell cycle regulatory proteins, mainly the cyclins and cyclin-related... -
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- Cell cycle regulators during human atrial development
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Kim WH, Joo CU, Ku JH, Ryu CH, Koh KN, Koh GY, Ko JK
- KMID: 759076
- Korean J Intern Med.
- 1998 Jul;13(2):77-82.
OBJECTIVES: The molecular mechanisms that regulate cardiomyocyte cell cycle and terminal differentiation in humans remain largely unknown. To determine which cyclins, cyclin dependent kinases (CDKs) and cyclin kinase inhibitors (CKIs)... -
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- Expression of Cell Cycle Related Genes in HL60 Cells Undergoing Apoptosis by X-irradiation
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Kim JH, Park IK
- KMID: 2323691
- J Korean Soc Ther Radiol Oncol.
- 1998 Dec;16(4):377-388.
PURPOSE: To evaluate changes in expression of cell cycle related genes during apoptosis induced in HL60 cells by X-irradiation to understand molecular biologic aspects in mechanism of radiation therapy. MATERIAL... -
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- Expression of Cell Cycle Control Genes in Korean Gastric Cancer Cell Lines
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Lim CC, Kim IH, Cho JW, Baek WK, Suh SI, Suh MH, Park JW, Kang JS, Sohn SS
- KMID: 2175098
- J Korean Cancer Assoc.
- 2000 Apr;32(2):279-287.
PURPOSE: In order to elucidate the roles of the cell cycle control genes in the carcinogenesis of Korean gastric cancer, the expressions of cyclin A, Dl, E, p16INK4a and Rb in... -
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- Effect of Selective Cyclooxygenase 2 Inhibitor in TCDD Pre-exposed Thyroid Papillary Carcinoma Cell Line
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Kim HS, Ahn KS, Lee JH, Chae YS, Won NH, Choi JS, Kim CH
- KMID: 2277513
- Korean J Pathol.
- 2011 Feb;45(1):1-8.
BACKGROUND: Cyclooxygenase 2 (COX-2) is related to carcinogenesis and progression of cancer. COX-2 has been detected in thyroid cancer. This suggests that COX-2 inhibitor may be useful to control the... -
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- p21WAFI mRNA Expression During HL60 Cell Differentiation
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Suh SI, Jung JA, Cho JW, Park MH, Paik SD, Suh WK, Suh MH
- KMID: 2001268
- J Korean Soc Microbiol.
- 1997 Aug;32(4):455-466.
p21waf1 is the mammalian cyclin-dependent kinase (CDK) inhibitor to be discovered. p21waf1 which is found to be induced by p53 mediates growth arrest by inhibiting G1 CDKs. But, recently p21waf1... -
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- Treatment with sodium butyrate and rapamycin inhibit growth of human cervical cancer cells
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Jeon YJ, Cho CH, Shin SJ, Kwon SH, Cha SD
- KMID: 2244544
- Korean J Gynecol Oncol.
- 2007 Sep;18(3):165-171.
OBJECTIVE: To evaluate whether mTOR inhibition by rapamycin can enhance the inhibitory effect of sodium butyrate, a histone deacetylase (HDAC) inhibitor on human cervical cancer cell line HeLa. METHODS: Cervical... -
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- Prognostic Value of Nuclear DNA Quantification and Cyclin A in Epithelial Ovarian Cancer
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Lee CS, Cho NH, Kim YT, Kim SH, Roh JH, Kim JW
- KMID: 2077055
- Korean J Obstet Gynecol.
- 2004 Jul;47(7):1309-1316.
OBJECTIVE: This study was carried out to investigate the relationship between DNA ploidy, S-phase fraction (SPF), expression of cyclin A and clinical prognostic factors including stage, grade, CA-125 and residual... -
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- Anti-proliferative Effect of 15,16-Dihydrotanshinone I Through Cell Cycle Arrest and the Regulation of AMP-activated Protein Kinase/Akt/mTOR and Mitogen-activated Protein Kinase Signaling Pathway in Human Hepatocellular Carcinoma Cells
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Hong JY, Park SH, Park HJ, Lee SK
- KMID: 2417368
- J Cancer Prev.
- 2018 Jun;23(2):63-69.
- doi: 10.15430/JCP.2018.23.2.63
BACKGROUND: 15,16-dihydrotanshinone I (DHTS) is a natural abietane diterpenoid that is mainly found in the roots of Salvia miltiorrhiza Bunge (Labiatae). DHTS exhibits a potential anti-proliferative effect in various human... -
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