- Chromosomal Losses are Associated with Hypomethylation of the Gene-Control Regions in the Stomach with a Low Number of Active Genes
-
Jung YC, Hong SJ, Kim YH, Kim SJ, Kang SJ, Choi SW, Rhyu MG
- KMID: 1107535
- J Korean Med Sci.
- 2008 Dec;23(6):1068-1089.
- doi: 10.3346/jkms.2008.23.6.1068
Transitional-CpG methylation between unmethylated promoters and nearby methylated retroelements plays a role in the establishment of tissue-specific transcription. This study examined whether chromosomal losses reducing the active genes in cancers... -
- CITED
-
- Close
- SHARE
-
- Close
- DNA Methylation and Expression Patterns of Key Tissue-specific Genes in Adult Stem Cells and Stomach Tissues
-
Hong SJ, Kang MI, Oh JH, Jung YC, Kim YH, Kim SJ, Choi SH, Seo EJ, Choi SW, Rhyu MG
- KMID: 1782016
- J Korean Med Sci.
- 2009 Oct;24(5):918-929.
- doi: 10.3346/jkms.2009.24.5.918
CpG-island margins and non-island-CpG sites round the transcription start sites of CpG-island-positive and -negative genes are methylated to various degrees in a tissue-specific manner. These methylation-variable CpG sites were analyzed... -
- CITED
-
- Close
- SHARE
-
- Close
- Methylation Profiles of CpG Island Loci in Major Types of Human Cancers
-
Park SY, Kim BH, Kim JH, Cho NY, Choi M, Yu EJ, Lee S, Kang GH
- KMID: 1713193
- J Korean Med Sci.
- 2007 Apr;22(2):311-317.
- doi: 10.3346/jkms.2007.22.2.311
Several reports have described aberrant methylation in various types of human cancers. However, the interpretation of methylation frequency in various human cancers has some limitations because of the different materials... -
- CITED
-
- Close
- SHARE
-
- Close
- Relationship Between the Extent of Chromosomal Losses and the Pattern of CpG Methylation in Gastric Carcinomas
-
Hong SJ, Kim YH, Choi YD, Min KO, Choi SW, Rhyu MG
- KMID: 1781762
- J Korean Med Sci.
- 2005 Oct;20(5):790-805.
- doi: 10.3346/jkms.2005.20.5.790
The extent of unilateral chromosomal losses and the presence of microsatellite instability (MSI) have been classified into high-risk (high- and baseline-level loss) and low-risk (low-level loss and MSI) stem-line genotypes... -
- CITED
-
- Close
- SHARE
-
- Close
