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Anesthetic management of living donor liver transplantation for complement factor H deficiency hemolytic uremic syndrome: a case report

Park SH, Kim GS

We experienced a living donor liver transplantation for a 26-month-old girl with complement factor H deficiency. Complement factor H is a plasma protein that regulates the activity of the complement...
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Complement Activation by Tobacco Infusion

Chung MH, Kim DH, Chung TH

  • KMID: 2282216
  • Korean J Prev Med.
  • 1985 Oct;18(1):91-98.
The capacity of tobacco infusions of Korean cigarettes to activate the complement pathway was investigated in vitro by hemolytic assay. Complement activity was studied using samples of normal rabbit serum...
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An overview of the synergy and crosstalk between pentraxins and collectins/ficolins: their functional relevance in complement activation

Ma YJ, Lee BL, Garred P

The complement system is an innate immune defense machinery comprising components that deploy rapid immune responses and provide efficient protection against foreign invaders and unwanted host elements. The complement system...
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Complement regulation: physiology and disease relevance

Cho H

The complement system is part of the innate immune response and as such defends against invading pathogens, removes immune complexes and damaged self-cells, aids organ regeneration, confers neuroprotection, and engages...
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A Case of Hypocomplementemic Henoch-Schonlein Purpura Presenting Features of Membranoproliferative Glomerulonephritis

Lee KA, Ha TS

  • KMID: 2279606
  • Korean J Pediatr.
  • 2005 Jan;48(1):81-84.
Henoch-Schonlein purpura (HSP) is a systemic disorder characterized by leukocytoclastic vasculitis that can affect multiple organs predominantly the skin, joints, gastrointestinal tract and kidney. Although the specific pathogenesis of HSP...
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Alterations of Complement C3 and C4 Levels in Delayed Testing

Lee ZY, Jearn LH, Park IK, Kim TY

BACKGROUND: In vitro levels of complement C3 and C4 proteins are sensitive to storage conditions. To avoid in vitro complement activation when testing is delayed, serum should be frozen at...
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Pathology of C3 Glomerulopathy

Shin SJ, Seong Y, Lim BJ

C3 glomerulopathy is a renal disorder involving dysregulation of alternative pathway complement activation. In most instances, a membranoproliferative pattern of glomerular injury with a prevalence of C3 deposition is observed...
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The activity of antimelanocyte autoantibodies in vitiligo patients

Park YK, Hann SK, Song MS, Yoon JK, Kim HI

  • KMID: 2303626
  • Korean J Dermatol.
  • 1991 Jun;29(3):391-398.
Several observation suggest that the antimelanocyte autoantibodies could play a role in melanocyte destruction. Some experiments indicate that melanocyte antibodies from patients with vitiligo can kill melanocyte in vitro. In...
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A Case of Type II Membranousproliferative Glomerulonephritis with Hump (Dense Deposit Disease)

Oh HJ, Yu MA, Lee YS, Kim MY, Kim SJ, Kang DH, Yun GI, Choi KB, Sung SH

Dense deposit disease (DDD), known as type II MPGN, is an uncommon form of glomerulonephritis. It is an acquired primary glomerular disease, characterised by electron microscopic evidence of a continous,...
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Prognostic utility of ADAMTS13 activity for the atypical hemolytic uremic syndrome (aHUS) and comparison of complement serology between aHUS and thrombotic thrombocytopenic purpura

Oh J, Oh D, Lee SJ, Kim JO, Kim NK, Chong SY, Huh JY, Baker RI, on behalf of the Korean TTP Registry Investigators

BACKGROUND: Atypical hemolytic uremic syndrome (aHUS) involves dysregulation of the complement system, but whether this also occurs in thrombotic thrombocytopenic purpura (TTP) remains unclear. Although these conditions are difficult to...
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Efficacies of the Modified Ultrafiltration and Peritoneal Dialysis in Removing Inflammatory Mediators After Pediatric Cardiac Surgery

Sung SC, Jung MH

  • KMID: 1915707
  • Korean J Thorac Cardiovasc Surg.
  • 2001 Oct;34(10):745-753.
BACKGROUND: Cardiopulmonary bypass induces an acute systemic inflammatory response mediated by complement activation and cytokine release. This response is likely to cause capillary leak syndrome and organ dysfunction in infants....
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Sequential Bilateral Lung Transplantation with Extracorporeal Membrane Oxygenation (ECMO) Support: A case report

Lee M, Kim K, Sung KI

  • KMID: 2062978
  • Korean J Thorac Cardiovasc Surg.
  • 2010 Feb;43(1):96-99.
Artificial lung support may be necessary in various conditions during the performance of bilateral lung transplantation, and cardiopulmonary bypass (CPB) has usually been used. Yet using the conventional CPB techniques...
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The anesthetic management of mitral valve replacement in the patient with paroxysmal nocturnal hemoglobinuria: A case report

Hong SJ, Lee JY, Chon JY, Park JH

Paroxysmal nocturnal hemoglobinuria (PNH) is a disorder of stem cells resulting in complement-mediated red cell lysis. Potential complications of cardiac surgery in patients with PNH include increased risk of infection...
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The relationship between eosinophilia and serum cytokine concentrations in maintenance hemodialysis patients

Park EM, Kim H, Jung SS, Yun JW, Koo ES, Lee KB, Keum DK

  • KMID: 2252797
  • Korean J Med.
  • 2003 May;64(5):561-566.
BACKGROUND: Eosinophilia in hemodialysis (HD) patients has been associated with allergic reactions to dialyzers and exaggerated activation of complement during HD. Complement activation can lead to cytokine production. The...
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Changes of Endotoxin Concentration in Dialysis Solution During Hemodialysis

Kang WT, Lee BC, Lee KS, Kim W, Park SK, Kang SK

  • KMID: 2254971
  • Korean J Nephrol.
  • 1998 May;17(3):453-460.
Endotoxin is a component of bacterial outer membrane. Endotoxin is generally a heat-stable toxin that has the various biological activities such as pyrogenicity, macrophage and complement activation. To determine the...
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Delivery in a Patient with Paroxysmal Nocturnal Hemoglobinuria Successfully Managed with Low Molecular Weight Heparin Therapy

Kim HB, Chang HJ, Yang JI, Kim HS, Ryu HS, Kim HC

  • KMID: 2272313
  • Korean J Obstet Gynecol.
  • 2004 Apr;47(4):748-751.
Paroxysmal nocturnal hemoglobinura is a very rare acquired clonal hematopoietic cell disorder leading to chronic intravascular hemolysis caused by abnormal complement activation. Pregnancy in a patient with paroxysmal nocturnal hemoglobinuria...
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The Inflammatory Response and Cardiac Repair After Myocardial Infarction

Nah DY, Rhee MY

One of the most important therapeutic targets of current cardiology practice is to determine optimal strategies for the minimization of myocardial necrosis and optimization of cardiac repair following an acute...
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Leukocyte Sequestration and Free Radical-Mediated Lung Injury in Ovine Cardiopulmonary bypass Using Membrane Oxygenator

Kim WG, Shin YC, Suh JW

  • KMID: 2288914
  • Korean J Thorac Cardiovasc Surg.
  • 1999 Nov;32(11):978-983.
BACKGROUND: Complement activation with transpulmonary leukocyte sequestration is considered a main mediator leading to ischemia-reperfusion lung(I-R) injury. We studied the role of leukocytes in the formation of I-R injury in...
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Generation of inflammatory cytokines and anaphylatoxins in whole blood under normal blood banking condition

Ki CS, Koo HH, Jung HL, Oh DJ, Kim DW

  • KMID: 2069263
  • Korean J Blood Transfus.
  • 1998 Dec;9(2):227-233.
BACKGROUND: Several recent studies have reported that generation of inflammatory cytokines and activation of complements may be associated with febrile nonhemolytic transfusion reactions (FNHTR). However, few data are available for...
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Acute Pulmonary Hypertension Associated with Protamine Neutralization of Systemic Heparinization during Open Heart Surgery

Hwang KS, Cho MW

Protamine sulfate, a strong polycationic polypeptide, combined with acidic heparin to form a neutral salt, eliminates the anticoagulating properties of heparin. Heparin reversal with protamine after cardiopulmonary bypass may complicate...
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