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Relationship between the Extent of DNA Damage and Gastritis in Normal and Helicobacter pylori-Infected Patients

Marie MA, Altahir IE

  • KMID: 2284213
  • Gut Liver.
  • 2011 Sep;5(3):315-320.
BACKGROUND/AIMS: The role of Helicobacter pylori in gastric carcinogenesis is unclear, but H. pylori infection is thought to predispose carriers to gastric cancer. The aim of this study was to...
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Comparison of the Protective Effect of Antioxidant Vitamins and Fruits or Vegetable Juices on DNA Damage in Human Lymphocyte Cells Using the Comet Assay

Jeon EJ, Park YK, Kim JS, Kang MH

  • KMID: 2078294
  • Korean J Nutr.
  • 2004 Jul;37(6):440-447.
In this study the in vitro protective effects of several antioxidant vitamins (vitamin C, alpha-tocopherol, beta-carotene), fruits and vegetables (strawberry, tangerine, orange and 100% orange juice, carrot juice), on the...
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The Effect of Obstructive Sleep Apnea on DNA Damage and Oxidative Stress

Kang IG, Jung JH, Kim ST

  • KMID: 2278472
  • Clin Exp Otorhinolaryngol.
  • 2013 Jun;6(2):68-72.
OBJECTIVES: Obstructive sleep apnea syndrome (OSAS) is associated with repeated hypoxia and re-oxygenation. This characteristic of OSAS may cause oxidative stress and DNA damage. However, the link of OSAS with...
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Genotoxicity Assessment of Erythritol by Using Short-term Assay

Chung YS, Lee M

  • KMID: 2317843
  • Toxicol Res.
  • 2013 Dec;29(4):249-255.
Erythritol is a sugar alcohol that is widely used as a natural sugar substitute. Thus, the safety of its usage is very important. In the present study, short-term genotoxicity assays...
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DNA Damage of Lymphocytes in Volunteers after 4 hours Use of Mobile Phone

Ji S, Oh E, Sul D, Choi JW, Park H, Lee E

  • KMID: 2283777
  • J Prev Med Public Health.
  • 2004 Nov;37(4):373-380.
OBJECTIVES: There has been gradually increasing concern about the adverse health effects of electromagnetic radiation originating from cell phones which are widely used in modern life. Cell phone radiation may...
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Hyperthermia-induced Apoptosis is Independent upon DNA Strand Breaks in Human Lymphoid Cells

Jung HJ, Ka WH, Hwang JN, Seo YR

  • KMID: 1611497
  • Korean J Physiol Pharmacol.
  • 2004 Dec;8(6):345-349.
Heat shock (43oC for 60 minutes) is sufficient to induce apoptosis in a wide number of cell lines. In this study, we asked whether DNA strand breaks are responsible for...
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Integrity of human sperm DNA assessed by the neutral comet assay and its relationship to semen parameters and clinical outcomes for the IVF-ET program

Chi HJ, Chung DY, Choi SY, Kim JH, Kim GY, Lee JS, Lee HS, Kim MH, Roh SI

OBJECTIVE: To explore potential relationships between sperm DNA integrity and both semen parameters and clinical outcomes. METHODS: Semen analysis of 498 samples was performed according to the 2010 criteria of the...
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Evaluation of Oxidative DNA Damage Using an Alkaline Single Cell Gel Electrophoresis (SCGE) Comet Assay, and the Protective Effects of N-Acetylcysteine Amide on Zearalenone-induced Cytotoxicity in Chang Liver Cells

Kang C, Lee H, Yoo YS, Hah DY, Kim CH, Kim E, Kim JS

  • KMID: 2317815
  • Toxicol Res.
  • 2013 Mar;29(1):43-52.
Zearalenone (ZEN) is a non-steroidal estrogenic mycotoxin produced by several species of Fusarium that are found in cereals and agricultural products. ZEN has been implicated in mycotoxicosis in farm animals...
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Effect of the Magnetized Water Supplementation on Lymphocyte DNA Damage in Mice Treated with Diethylnitrosamine

Lee HJ, Jo HR, Jeon EJ, Kang MH

Water gets magnetically charged when it is contacted with a magnet. Although magnetic water products have been promoted since the 1930's, they have received very little recognition due to questionable...
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Appropriate In Vitro Methods for Genotoxicity Testing of Silver Nanoparticles

Kim HR, Park YJ, Shin DY, Oh SM, Chung KH

  • KMID: 2380115
  • Environ Health Toxicol.
  • 2013 ;28(1):e2013003.
OBJECTIVES: We investigated the genotoxic effects of 40-59 nm silver nanoparticles (Ag-NPs) by bacterial reverse mutation assay (Ames test), in vitro comet assay and micronucleus (MN) assay. In particular, we...
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Comparison of antioxidant activity and prevention of lymphocyte DNA damage by fruit and vegetable juices marketed in Korea

Cho M, Lee HJ, Kang MH, Min H

PURPOSE: Fruit and vegetable juices are known to be rich sources of antioxidants, which have beneficial effects on diseases caused by oxidative stress. The purpose of this study was to...
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Protective Effect of Yellow-Green Vegetable Juices on DNA Damage in Chinese Hamster Lung Cell Using Comet Assay

Jeon EJ, Kim JS, Park YK, Kim TS, Kang MH

  • KMID: 2235854
  • Korean J Nutr.
  • 2003 Jan;36(1):24-31.
The present study was attempted to investigate the antioxidant capacity of popular yellow-green vegetable juices (kale, Angelica keishei, carrot, small water dropwort) and to investigate the effect of vegetable juices...
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Effect of Microsurgical Varicocelectomy on Human Sperm Nucleus DNA Integrity

Kim GY, Lee JS, Chi HJ, Kim JH

  • KMID: 2071002
  • Korean J Reprod Med.
  • 2010 Sep;37(3):245-251.
OBJECTIVE: Human sperm nucleus DNA damage may negatively affect pregnancy outcome, and the spermatozoa of infertile men have more DNA damage than that of fertile men. The aim of this...
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The renoprotective effects of mannitol and udenafil in renal ischemia-reperfusion injury model

Özlülerden Y, Toktaş C, Aybek H, Küçükatay V, Şen Türk N, Zumrutbas

PURPOSE: The aim of this study was to investigate and compare the effects of udenafil and mannitol in an experimental renal ischemia-reperfusion (I/R) injury model. MATERIALS AND METHODS: A total of...
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Plasma, Tissue Thiobarbituric Acid Reactive Substance and Lymphocyte Oxidative DNA Damage in Mouse Fed Gamma Irradiated Diet

Jang HH, Kang MH, Yang JS, Ly SY

  • KMID: 2269649
  • Korean J Nutr.
  • 2003 Apr;36(3):255-261.
Food irradiation has been steadily increasing in many countries in line with increasing international trade and concerns about naturally occurring harmful contaminants in food. Although irradiation provides an excellent safeguard...
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Effect of saffron (Crocus sativus L.) on sodium valporate induced cytogenetic and testicular alterations in albino rats

Sakr SA, Zowail ME, Marzouk AM

The present study investigated the cytogenetic and testicular damage induced by the antiepileptic drug, sodium valporate (SVP) in albino rats and the effect of saffron aqueous extracts. Treating rats with...
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DNA Damage in Lymphocytes after Hair Dyeing and Related Factors among Women Volunteers

Cho JA, Oh EH, Sul DG, Lee EI

  • KMID: 2283318
  • Korean J Prev Med.
  • 2002 Nov;35(4):275-281.
OBJECTIVES: To evaluate the DNA damage by hair dyeing in human lymphocytes. METHODS: Comet assays were carried out to evaluate the DNA damage in lymphocytes by hair dyeing. Twenty subjects were...
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Comparative evaluation of the mutagenicity and genotoxicity of smoke condensate derived from Korean cigarettes

Kim HR, Lee JE, Jeong MH, Choi SJ, Lee K, Chung KH

OBJECTIVES: Cigarette smoking is associated with carcinogenesis owing to the mutagenic and genotoxic effects of cigarette smoke. The aim of this study was to evaluate the mutagenic and genotoxic effects...
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Comparison of lymphocyte DNA damage levels and total antioxidant capacity in Korean and American diet

Lee MY, Kim HA, Kang MH

BACKGROUND/OBJECTIVE: This study aims to measure the in vitro antioxidant capacity of Korean diet (KD) with American diet (AD) as a control group and to examine the ex vivo DNA...
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Effects of lymphocyte DNA damage levels in Korean plant food groups and Korean diet regarding to glutathione S-transferase M1 and T1 polymorphisms

Kim HA, Lee MY, Kang MH

PURPOSE: GST (glutathione S-transferase) M1 and T1 gene polymorphisms are known to affect antioxidant levels. This study was carried out to evaluate genetic susceptibility by measuring the effect of DNA...
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