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Investigation into the Effects of Mosapride on Motility of Guinea Pig Stomach, Ileum, and Colon

Ji SW, Park HJ, Cho JS, Lim JH, Lee SI

Mosapride citrate (Mosapride) is a new prokinetic agent that enhances the gastrointestinal (GI) motility by stimulation of 5-HT4 receptors. This agent stimulates acetylcholine release from enteric cholinergic neurons in the...
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Effect of Itopride Hydrochloride on the Ileal and Colonic Motility in Guinea Pig In Vitro

Lim HC, Kim YG, Lim JH, Kim HS, Park H

PURPOSE: Itopride hydrochloride (itopride) inhibits acetylcholinesterase (AChE) and antagonizes dopamine D(2) receptor, and has been used as a gastroprokinetic agent. However, its prokinetic effect on the small bowel or colon...
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The Effect of Urocortin 1 on Motility in Isolated, Vascularly Perfused Rat Colon

You IY, Lee S, Kim KB, Lee HS, Jang JS, Yeon M, Han JH, Yoon SM, Chae HB, Park SM, Youn SJ

BACKGROUND/AIMS: Urocortin 1, a corticotropin-releasing factor related peptide, increases colonic motility under stressful conditions. We investigated the effect of urocortin 1 on colonic motility using an experimental model with isolated...
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Effects of Tamoxifen on the Voltage-dependent Ionic Currents in Mouse Colonic Smooth Muscle Cells

Lee DM, Chang SJ, Park CG, Kim MW, Lim GH, Choi S, Yeum CH, Yoon PJ, Jun JY

  • KMID: 772862
  • Korean J Gastroenterol.
  • 2005 Nov;46(5):388-395.
BACKGROUND/AIMS: Tamoxifen is a widely used anticancer drug for breast cancer with frequent gastrointestinal side effects. Changes in gastrointestinal motility is associated with altered activities of membrane ion channels....
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Comparative Study on Bowel Preparation Efficacy of Ascorbic Acid Containing Polyethylene Glycol by Adding Either Simethicone or 1 L of Water in Health Medical Examination Patients: A Prospective Randomized Controlled Study

Yeo SH, Kwak JH, Kim YU, Kwon TH, Park JB, Park JH, Lee YK, Lim YJ, Yang CH

BACKGROUND/AIMS: There are no studies that looked into the bubble eliminating efficacy of polyethylene glycol with ascorbic acid (PEGA), which has been one of the shortcomings of polyethylene glycol (PEG)....
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Sodium Picosulfate with Magnesium Citrate (SPMC) Plus Laxative Is a Good Alternative to Conventional Large Volume Polyethylene Glycol in Bowel Preparation: A Multicenter Randomized Single-Blinded Trial

Kim HG, Huh KC, Koo HS, Kim SE, Kim JO, Kim TI, Kim HS, Myung SJ, Park DI, Shin JE, Yang DH, Lee SH, Lee JS, Lee CK, Chang DK, Joo YE, Cha JM, Hong SP, Kim HJ

BACKGROUND/AIMS: We investigated whether sodium picosulfate with magnesium citrate (SPMC) plus bisacodyl compares favorably with conventional polyethylene glycol (PEG) with respect to bowel cleansing adequacy, compliance, and safety. METHODS: We performed...
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