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Trends of clinical trials from 2014 to 2016 in South Korea

Huh KY, Hwang JG, Lee S

Mandatory registration of clinical trials in public registry can ensure the transparency of clinical trials. Public clinical trial registry of can provide current chronological and geographical distribution of clinical trial...
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Are You "Tilting at Windmills" or Undertaking a Valid Clinical Trial?

Steeves JD, Zariffa J, Kramer JL

In this review, several aspects surrounding the choice of a therapeutic intervention and the conduct of clinical trials are discussed. Some of the background for why human studies have evolved...
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Independent Data Monitoring Committees: Review of Current Guidelines

Lee BR, Lee KE

BACKGROUND: There has been on increasing emphasis on the importance of monitoring the safety of participants in a clinical trial to protect patients and maintain the integrity of the trial....
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Clinicoepidemiological research designs in childhood allergic diseases

Yang HJ

Clinical epidemiology is defined as a method for investigating the distribution and determinants of diseases and for applying this knowledge in their prevention, and simply means application of epidemiological methods...
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Knowledge and Perception about Clinical Research Shapes Behavior: Face to Face Survey in Korean General Public

Choi YJ, Beck SH, Kang WY, Yoo S, Kim SY, Lee JS, Burt T, Kim TW

Considering general public as potential patients, identifying factors that hinder public participation poses great importance, especially in a research environment where demands for clinical trial participants outpace the supply. Hence,...
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Using 2-mSv Appendiceal CT in Usual Practice for Adolescents and Young Adults: Willingness Survey of 579 Radiologists, Emergency Physicians, and Surgeons from 20 Hospitals

Kim HJ, Lee KH, Kim M, Park SB, Ko Y, LOCAT Group

OBJECTIVE: To survey care providers' willingness to use 2-mSv computed tomography (CT) in their usual practice for adolescents and young adults with suspected appendicitis. MATERIALS AND METHODS: An ethical committee approved...
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Effect of the Telephone-Delivered Nutrition Education on Dietary Intake and Biochemical Parameters in Subjects with Metabolic Syndrome

Kim J, Bea W, Lee K, Han J, Kim S, Kim M, Na W, Sohn C

As prevalence of metabolic syndrome has rapidly increased over the past decade, lifestyle changes including dietary habits are considered as a therapeutic cornerstone for metabolic syndrome, cardiovascular complications and type...
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Results from the safety interim analysis of the adjuvant chemoradiotherapy in stomach tumors 2 trial: a multicenter, randomized phase III clinical trial

Park SH, Lee J, Sohn TS, Lim DH, Kim KM, An JY, Choi MG, Lee JH, Bae JM, Kim S, Lee SJ, Kim ST, Park JO, Park YS, Lim HY, Kang WK

PURPOSE: The Adjuvant chemoRadioTherapy In Stomach Tumors 2 (ARTIST 2) trial was conducted to compare the efficacy between adjuvant chemotherapy regimens and chemoradiotherapy in D2-resected, node-positive, stage 2 or 3...
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Clinical Trial of a Calcium Channel Blocker in Patients with Aneurysmal Subarachnoid Hemorrhage

Lee KS, Lee KC, Choi JU

Forty-three patients with aneurysmal subarachnoid hemorrhage entered a nimodipine trial in the Department of Neurosurgery, Yonsei university to determine the efficacy of the drug in preventing vasospasm and to evaluate...
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A Meta-Analysis of Intervention Research for Posttraumatic Growth in Cancer Patients

Park MH, Park JS

PURPOSE: The objective of this study was to analyze effect size of the intervention studies for posttraumatic growth in patients with cancer. METHODS: A total of 871 studies published between 2000...
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Assessment of statistical power for covariate effects in data from phase I clinical trials

Kim Y, Son H, Son M, Lee D, Heo YA, Park K

One of the important purposes in population pharmacokinetic studies is to investigate the relationships between parameters and covariates to describe parameter variability. The purpose of this study is to evaluate...
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Analysis of Research on Adherence for Secondary Prevention in Patients with Coronary Artery Disease in Korea

Son YJ, Kim SH, Song HS

  • KMID: 2295682
  • J Korean Acad Fundam Nurs.
  • 2010 Nov;17(4):575-587.
PURPOSE: The purpose of this study was to analyze the research on adherence for secondary prevention in patients with coronary artery disease (CAD) in Korea, and to identify the strategies...
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Exogenous surfactant replacement therapy of hyaline membrane disease in premature infants

Namgung R, Lee C, Suh JS, Park KI, Han DG

We conducted a clinical trial to assess whether surfactant-TA given within the first six hours of life could improve oxygenation and reduce the ventilatory support in premature infants with...
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Phytoestrogens and Bone Metabolism

Jeon GH, Kang BM

  • KMID: 2314139
  • Osteoporosis.
  • 2013 Dec;11(3):105-113.
Although most gynecologists had prescribed estrogen with or without progestin for their menopausal patients before the publication of Women's health Initiative (WHI) trial findings, only 35 to 40% of women...
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Cognitive Behavioral Therapy for Psychological Distress, Self Care and Quality of Life in Patients with Cancer: A Meta-analysis

Oh PJ, Lee EA

  • KMID: 2298243
  • Korean J Adult Nurs.
  • 2013 Aug;25(4):377-388.
PURPOSE: The purpose of this study was to assess the effects of cognitive behavioral therapy (CBT) on depression, anxiety, self care behavior and quality of life in cancer patients. METHODS: Two...
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Psychometrics of Health-Related Hardiness Scale for Korean Elderly

Suh YO, June KJ, Song R, Um YR

  • KMID: 2291363
  • J Korean Acad Adult Nurs.
  • 1997 Dec;9(3):398-409.
The purpose of this study was to test psychometric properties Health-Related Hardiness Scale(HRHS) for Korean elderly. HRHS has been developed by Pollock to measure the effect of hardiness in individuals...
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Chronic Rhinosinusitis: Therapeutic Efficacy of Anti-Inflammatory and Antibiotic Approaches

Kariyawasam HH, Scadding G

Despite the high prevalence of chronic rhinosinusitis (CRS) worldwide, the exact pathogenesis of the disease remains unknown. Even with therapeutic intervention, treatment response is often only partial and frequently ineffective....
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Measuring the stress of the surgeons in training and use of a novel interventional program to combat it

Christakis I, Pagkratis , Varvogli L, Darviri C, Chroussos

  • KMID: 2324827
  • J Korean Surg Soc.
  • 2012 May;82(5):312-316.
PURPOSE: Stress poses a serious risk for training surgeons since their performance and well-being in reflected in patients' health. This study focuses on measuring the stress of training surgeons and...
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Effect of Deer Antler Drink Supplementation on Blood Pressure, Blood Glucose and Lymphocyte DNA Damage in Type 2 Diabetic Patients

Kim HY, Jeon EJ, Park YK, Kang MH

  • KMID: 2269804
  • Korean J Nutr.
  • 2004 Nov;37(9):794-800.
Deer Antler has been known for its traditional oriental medicinal properties and has been widely used to promote growth, boost immune function, treat blood loss and chronic joint pain. Recent...
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Medical Nutrition Therapy based on Nutrition Intervention for a Patient with Chronic Obstructive Pulmonary Disease

Seo SH

Chronic obstructive pulmonary disease (COPD) is a major cause of disability, and according to statistics from the World Health Organization, COPD is the fourth leading cause of death overall in...
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