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Correlation between Claudins Expression and Prognostic Factors in Prostate Cancer

Seo KW, Kwon YK, Kim BH, Kim CI, Chang HS, Choe MS, Park CH

  • KMID: 2314836
  • Korean J Urol.
  • 2010 Apr;51(4):239-244.
PURPOSE: The purpose of this study was to evaluate the correlation between the expression of claudins and prognostic factors in patients with prostate cancer. MATERIALS AND METHODS: The subjects of...
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Effects of High Glucose and Dexamethasone on the Permeability in Trabecular Meshwork Cells

Kang SH, Kim JW

PURPOSE: To investigate the effects of high glucose (HG) and dexamethasone (DEX) on the survival and permeability of trabecular meshwork cells (HTMC), and associated changes in tight junctions. METHODS: Primary cultured...
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Indol-3-Carbinol Regulated Tight Junction Permeability and Associated-Protein Level and Suppressed Cell Invasion in Human Colon Cancer Cell Line, HT-29

Kim SO, Choi YH, Choe WK

  • KMID: 2261191
  • Korean J Nutr.
  • 2008 Jan;41(1):13-21.
To determine whether indol-3-carbinol (I3C, C9H9NO), an autolysis product of a glucosinolate and a glucobrassicin in vegetables, regulated tight junction proteins (TJ) and suppressed cell invasion in colon cancer cells,this...
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Impact of the Endothelial Tight Junction Protein Claudin-5 on Clinical Profiles of Patients With COPD

Kim BG, Lee PH, Lee SH, Baek AR, Park JS, Lee J, Park SW, Kim DJ, Park CS, Jang AS

PURPOSE: The tight junction protein claudin-5 (CLDN5) is critical to the control of endothelial cellular polarity and pericellular permeability. The role of CLDN5 in chronic obstructive pulmonary disease (COPD) remains...
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Chlorogenic Acid Decreases Retinal Vascular Hyperpermeability in Diabetic Rat Model

Shin JY, Sohn J, Park KH

To evaluate the effect of chlorogenic acid (CGA), a polyphenol abundant in coffee, on retinal vascular leakage in the rat model of diabetic retinopathy, Sprague-Dawley rats were divided into four...
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Resveratrol attenuates lipopolysaccharide-induced dysfunction of blood-brain barrier in endothelial cells via AMPK activation

Hu M, Liu B

Resveratrol, a phytoalexin, is reported to activate AMP-activated protein kinase (AMPK) in vascular cells. The blood-brain barrier (BBB), formed by specialized brain endothelial cells that are interconnected by tight junctions,...
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Dehydroascorbic Acid Attenuates Ischemic Brain Edema and Neurotoxicity in Cerebral Ischemia: An in vivo Study

Song J, Park J, Kim JH, Choi JY, Kim JY, Lee KM, Lee JE

Ischemic stroke results in the diverse phathophysiologies including blood brain barrier (BBB) disruption, brain edema, neuronal cell death, and synaptic loss in brain. Vitamin C has known as the potent...
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Arg-Leu-Tyr-Glu Suppresses Retinal Endothelial Permeability and Choroidal Neovascularization by Inhibiting the VEGF Receptor 2 Signaling Pathway

Park W, Baek YY, Kim J, Jo DH, Choi S, Kim JH, Kim T, Kim S, Park M, Kim JY, Won MH, Ha KS, Kim JH, Kwon YG, Kim YM

Vascular endothelial growth factor (VEGF) plays a pivotal role in pathologic ocular neovascularization and vascular leakage via activation of VEGF receptor 2 (VEGFR2). This study was undertaken to evaluate the...
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