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Toll-like Receptor 2 in Autoimmune Inflammation

Marks KE, Cho K, Stickling C, Reynolds JM

TLR signaling is critical for broad scale immune recognition of pathogens and/or danger molecules. TLRs are particularly important for the activation and the maturation of cells comprising the innate immune...
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Correction to: A Novel Method to Differentiate Tonsil-Derived Mesenchymal Stem Cells In Vitro into Estrogen-Secreting Cells

Kim HY, Lee Y, Yoon HS, Kim YH, Cho KA, Woo SY, Kim HS, Park BY, Jung SC, Jo I, Park WJ, Park JW, Ryu KH

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A Novel Method to Differentiate Tonsil-Derived Mesenchymal Stem Cells In Vitro into Estrogen-Secreting Cells

Kim HY, Lee Y, Yoon HS, Kim YH, Cho KA, Woo SY, Kim HS, Park BY, Jung SC, Jo I, Park WJ, Park JW, Ryu KH

BACKGROUND: The advantages of tonsil-derived mesenchymal stem cells (TMSCs) over other mesenchymal stem cells (MSCs) include higher proliferation rates, various differentiation potentials, efficient immune-modulating capacity, and ease of obtainment. Specifically,...
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Toll‐Like Receptor 7 (TLR7) Mediated Transcriptomic Changes on Human Mast Cells

Cho KA, Choi DW, Park M, Kim YH, Woo SY

Background: Mast cells are skin immune sentinels located in the upper dermis, where wheal formation and sensory nerve stimulation take place. Skin inflammation is occasionally accompanied by mast cell-driven responses...
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Efficacy and Safety of Matrix Shave Biopsy Using a Razor Blade for the Diagnosis of Longitudinal Melanonychia

Lim BR, Cho KH, Park K

  • KMID: 2512402
  • Korean J Dermatol.
  • 2021 Jan;59(1):38-44.
Background: Longitudinal melanonychia (LM) can be caused by a variety of benign and malignant conditions. Nail matrix biopsy is necessary for the diagnosis of LM; however, physicians hesitate to perform...
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A Fully Immersive Virtual Reality Method for Upper Limb Rehabilitation in Spinal Cord Injury

Lim DY, Hwang DM, Cho KH, Moon CW, Ahn SY

Objective To determine whether a fully immersive virtual reality (VR) intervention combined with conventional rehabilitation (CR) can improve upper limb function more than CR alone in patients with spinal cord...
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Management of Urinary Incontinence With Underactive Bladder: A Review

Cho KJ, Kim JC

Urinary incontinence is caused by storage function failure, while underactive bladder (UAB) is caused by a decline in detrusor contractility and voiding dysfunction. As the treatment mechanisms for incontinence and...
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Changes in uroplakin expression in the urothelium of patients with ulcerative interstitial cystitis/ bladder pain syndrome

Cho KJ, Lee KS, Choi JB, Koh JS, Kim JC

Purpose: We evaluated changes in the expression of uroplakin (UP) in the urothelium of patients with ulcerative interstitial cystitis/ bladder pain syndrome (IC/BPS). Materials and Methods: Bladder samples were collected from...
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Glucagon-Like Peptide-1 Receptor Agonist Differentially Affects Brain Activation in Response to Visual Food Cues in Lean and Obese Individuals with Type 2 Diabetes Mellitus

Bae JH, Choi HJ, Cho KIK, Kim LK, Kwon JS, Cho YM

Background: To investigate the effects of a glucagon-like peptide-1 receptor agonist on functional brain activation in lean and obese individuals with type 2 diabetes mellitus (T2DM) in response to visual...
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Differential Activation of Macrophages Based on Their Environment in Advanced Age

Lee DY, Lim JS, Cho KA

The macrophage displays functional and phenotypic diversity, which appears, in no small part, to stem from the ability of macrophages to adapt functionally to changes in their tissue microenvironment. Here,...
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The Effect of Daily Low Dose Tadalafil on Cerebral Perfusion and Cognition in Patients with Erectile Dysfunction and Mild Cognitive Impairment

Choi JB, Cho KJ, Kim JC, Kim CH, Chung YA, Jeong HS, Shim YS, Koh JS

OBJECTIVE: The aims of this study were to investigate the effects of daily low-dose tadalafil on cognitive function and to examine whether there was a change in cerebral blood flow...
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Effect of tDCS on Aberrant Functional Network Connectivity in Refractory Hallucinatory Schizophrenia: A Pilot Study

Yoon YB, Kim M, Lee J, Cho KI, Kwak S, Lee TY, Kwon JS

We aim to investigate the effect of fronto-temporal transcranial direct current stimulation (tDCS) on the interactions among functional networks and its association with psychotic symptoms. In this pilot study, we...
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Alpha-1 Adrenergic Receptor Blockers for the Treatment of Lower Urinary Tract Symptoms in Women: A Systematic Review and Meta-Analysis

Kim DK, Lee JY, Jung JH, Kim JH, Hah YS, Hong CH, Cho KS

PURPOSE: To assess the effectiveness of alpha-1 adrenergic receptor blockers (α1-blockers) in the treatment of female lower urinary tract symptoms (LUTS). METHODS: A literature search was conducted using the PubMed/MEDLINE, Embase,...
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Role of adjuvant cisplatin-based chemotherapy following radical cystectomy in locally advanced muscle-invasive bladder cancer: Systematic review and meta-analysis of randomized trials

Kim DK, Lee JY, Jung JH, Hah YS, Cho KS

PURPOSE: We purposed to assess the effects of adjuvant chemotherapy (ACH) on survival outcomes in patients with locally advanced muscle-invasive bladder cancer (MIBC) who are treated with radical cystectomy (RC). MATERIALS...
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Conditioned Medium from Tonsil-Derived Mesenchymal Stem Cells Relieves CClâ‚„-Induced Liver Fibrosis in Mice

Kim YH, Cho KA, Park M, Kim HS, Park JW, Woo SY, Ryu KH

BACKGROUND: The liver is an organ with remarkable regenerative capacity; however, once chronic fibrosis occurs, liver failure follows, with high mortality and morbidity rates. Continuous exposure to proinflammatory stimuli exaggerates...
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Impact of Bladder Neck Stiffness on Lower Urinary Tract Symptoms in Patient With Benign Prostatic Hyperplasia

Kwon JK, Jung HD, Cho KS

PURPOSE: We evaluated the impact of bladder neck stiffness on lower urinary tract symptoms in the patient with benign prostatic hyperplasia using elastography. MATERIALS AND METHODS: A total of 384 patients...
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Determining the Reliability of a New Method for Measuring Joint Range of Motion Through a Randomized Controlled Trial

Ahn SY, Ko H, Yoon JO, Cho SU, Park JH, Cho KH

OBJECTIVE: To compare the reliability and validity of the Korean range of motion standard protocol (KRSP) for measuring joint range of motion (ROM) with those of the conventional ROM measurement...
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Impact of Cerebrovascular Disease on Survival Benefits from Local Treatment in Patients with De Novo Metastatic Hormone-Sensitive Prostate Cancer

Kim TJ, Yu YD, Park DS, Rha KH, Hong SJ, Cho KS, Chung BH, Koo KC

PURPOSE: Local treatment has become a treatment option for patients with de novo metastatic hormone-sensitive prostate cancer (mHSPC). Subgroup analyses based on a history of cerebrovascular disease (CVD) were performed...
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Telmisartan increases hepatic glucose production via protein kinase C ζ-dependent insulin receptor substrate-1 phosphorylation in HepG2 cells and mouse liver

Cho KW, Cho DH

BACKGROUND: Dysregulation of hepatic glucose production (HGP) contributes to the development of type 2 diabetes mellitus. Telmisartan, an angiotensin II type 1 receptor blocker (ARB), has various ancillary effects in...
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Factors Associated With Early Recovery of Stress Urinary Incontinence Following Holmium Laser Enucleation of the Prostate in Patients With Benign Prostatic Enlargement

Cho KJ, Koh JS, Choi JB, Kim JC

PURPOSE: To investigate factors associated with early recovery of stress urinary incontinence (SUI) following holmium laser enucleation of the prostate (HoLEP) in patients with benign prostatic enlargement (BPE). METHODS: The medical...
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